Illumination of a progressive allosteric mechanism mediating the glycine receptor activation

Posted by klaurent UCSD / Salk

Kavli Affiliate: Jean Pierre Changeux | Authors: Sophie Shi, Solene N Lefebvre, Laurie Peverini, Adrien H Cerdan, Marc Gielen, Jean-Pierre Changeux, Marco CECCHINI and Pierre-Jean Corringer | Summary: Pentameric ligand-gated ion channel mediate signal transduction at chemical synapses by transiting between resting and open states upon neurotransmitter binding. Here, we investigate the gating transition of […]


Continue.. Illumination of a progressive allosteric mechanism mediating the glycine receptor activation

Large-Scale Crosstalk-Corrected Thermo-Optic Phase Shifter Arrays in Silicon Photonics

Posted by klaurent Caltech

Kavli Affiliate: Ali Hajimiri | Summary:We introduce a thermo-optic phase shifter (TOPS) array architecture with independent phase control of each phase shifter for large-scale and high-density photonic integrated circuits with two different control schemes: pulse amplitude modulation (PAM) and pulse width modulation (PWM). We realize a compact spiral TOPS and a 288-element high-density row-column TOPS […]


Continue.. Large-Scale Crosstalk-Corrected Thermo-Optic Phase Shifter Arrays in Silicon Photonics