Illumination of a progressive allosteric mechanism mediating the glycine receptor activation

Posted by klaurent UCSD / Salk

Kavli Affiliate: Jean Pierre Changeux | Authors: Sophie Shi, Solene N Lefebvre, Laurie Peverini, Adrien H Cerdan, Marc Gielen, Jean-Pierre Changeux, Marco CECCHINI and Pierre-Jean Corringer | Summary: Pentameric ligand-gated ion channel mediate signal transduction at chemical synapses by transiting between resting and open states upon neurotransmitter binding. Here, we investigate the gating transition of […]


Continue.. Illumination of a progressive allosteric mechanism mediating the glycine receptor activation

Accurate Scoliosis Vertebral Landmark Localization on X-ray Images via Shape-constrained Multi-stage Cascaded CNNs

Posted by klaurent Peking

Kavli Affiliate: Li Xin Li | First 5 Authors: Zhiwei Wang, Jinxin Lv, Yunqiao Yang, Yuanhuai Liang, Yi Lin | Summary: Vertebral landmark localization is a crucial step for variant spine-related clinical applications, which requires detecting the corner points of 17 vertebrae. However, the neighbor landmarks often disturb each other for the homogeneous appearance of […]


Continue.. Accurate Scoliosis Vertebral Landmark Localization on X-ray Images via Shape-constrained Multi-stage Cascaded CNNs

Large-Scale Crosstalk-Corrected Thermo-Optic Phase Shifter Arrays in Silicon Photonics

Posted by Caltech

Kavli Affiliate: Ali Hajimiri | First 5 Authors: Volkan Gurses, Reza Fatemi, Aroutin Khachaturian, Ali Hajimiri, | Summary: We introduce a thermo-optic phase shifter (TOPS) array architecture with independent phase control of each phase shifter for large-scale and high-density photonic integrated circuits with two different control schemes: pulse amplitude modulation (PAM) and pulse width modulation […]


Continue.. Large-Scale Crosstalk-Corrected Thermo-Optic Phase Shifter Arrays in Silicon Photonics