The physical basis of self-organization of the mammalian oocyte spindle

Kavli Affiliate: Daniel J. Needleman | First 5 Authors: Colm P Kelleher, Daniel J Needleman, , , | Summary: To prepare gametes with the appropriate number of chromosomes, mammalian oocytes undergo two sequential cell divisions. During each division, a large, long-lived, microtubule-based organelle called the meiotic spindle assembles around condensed chromosomes. Although meiotic spindles have […]


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Long-Range Repulsion Between Chromosomes in Mammalian Oocyte Spindles

Kavli Affiliate: Daniel J. Needleman | First 5 Authors: Colm P Kelleher, Yash Rana, Daniel J Needleman, , | Summary: During eukaryotic cell division, a microtubule-based structure called the spindle exerts forces on chromosomes, thereby organizing and segregating them Extensive work demonstrates that the forces acting parallel to the spindle axis, including those responsible for […]


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Photonic Elementary Cellular Automata for Simulation of Complex Phenomena

Kavli Affiliate: Alireza Marandi | First 5 Authors: Gordon H. Y. Li, Christian R. Leefmans, James Williams, Alireza Marandi, | Summary: Cellular automata are a class of computational models based on simple rules and algorithms that can simulate a wide range of complex phenomena. However, when using conventional computers, these ‘simple’ rules are only encapsulated […]


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A Biophysical Basis for Learning and Transmitting Sensory Predictions

Kavli Affiliate: Larry Abbott, Nathaniel Sawtell | Authors: Salomon Zev Muller, Larry F Abbott and Nathaniel B Sawtell | Summary: Abstract Homeostatic (anti-Hebbian) forms of synaptic are effective at eliminating “prediction errors” that signal the differences between predicted and actual sensory input. However, such mechanisms appear to preclude the possibility of transmitting the resulting predictions […]


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Preservation of prehearing spontaneous activity enables early auditory system development in deaf mice

Kavli Affiliate: Dwight Bergles, Patrick Kanold | Authors: Calvin J Kersbergen, Travis A Babola, Patrick O Kanold and Dwight E Bergles | Summary: ABSTRACT Intrinsically generated neural activity propagates through the developing auditory system to promote maturation and refinement of sound processing circuits prior to hearing onset. This early patterned activity is induced by non-sensory […]


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Stochastic thermodynamic bounds on logical circuit operation

Kavli Affiliate: David T. Limmer | First 5 Authors: Phillip Helms, David T. Limmer, , , | Summary: Using a thermodynamically consistent, mesoscopic model for modern complementary metal-oxide-semiconductor transistors, we study an array of logical circuits and explore how their function is constrained by recent thermodynamic uncertainty relations when operating near thermal energies. For a […]


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Stochastic thermodynamic bounds on logical circuit operation

Kavli Affiliate: David T. Limmer | First 5 Authors: Phillip Helms, Songela W. Chen, David T. Limmer, , | Summary: Using a thermodynamically consistent, mesoscopic model for modern complementary metal-oxide-semiconductor transistors, we study an array of logical circuits and explore how their function is constrained by recent thermodynamic uncertainty relations when operating near thermal energies. […]


Continue.. Stochastic thermodynamic bounds on logical circuit operation

Stochastic thermodynamic bounds on logical circuit operation

Kavli Affiliate: David T. Limmer | First 5 Authors: Phillip Helms, Songela W. Chen, David T. Limmer, , | Summary: Using a thermodynamically consistent, mesoscopic model for modern complementary metal-oxide-semiconductor transistors, we study an array of logical circuits and explore how their function is constrained by recent thermodynamic uncertainty relations when operating near thermal energies. […]


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Gate-tunable heavy fermions in a moiré Kondo lattice

Kavli Affiliate: Jie Shan | First 5 Authors: Wenjin Zhao, Bowen Shen, Zui Tao, Zhongdong Han, Kaifei Kang | Summary: The Kondo lattice, describing a matrix of local magnetic moments coupled via spin-exchange interactions to itinerant conduction electrons, is a prototype of strongly correlated quantum matter. Traditionally, Kondo lattices are realized in intermetallic compounds containing […]


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TESS Giants Transiting Giants III: An eccentric warm Jupiter supports a period-eccentricity relation for giant planets transiting evolved stars

Kavli Affiliate: Edward H. Morgan | First 5 Authors: Samuel K. Grunblatt, Nicholas Saunders, Ashley Chontos, Soichiro Hattori, Dimitri Veras | Summary: The fate of planets around rapidly evolving stars is not well understood. Previous studies have suggested that relative to the main sequence population, planets transiting evolved stars ($P$ $<$ 100 d) tend to […]


Continue.. TESS Giants Transiting Giants III: An eccentric warm Jupiter supports a period-eccentricity relation for giant planets transiting evolved stars