Flexible, Scalable, High Channel Count Stereo-Electrode for Recording in the Human Brain

Kavli Affiliate: Shadi Dayeh, Eric Halgren/p> | Authors: Keundong Lee, Angelique C Paulk, Yun Goo Ro, Daniel R Cleary, Karen J Tonsfeldt, Yoav Kfir, John Pezaris, Youngbin Tchoe, Jihwan Lee, Andrew M Bourhis, Ritwik Vatsyayan, Samantha M Russman, Jimmy C Yang, Amy Baohan, Mark Richardson, Ziv M Williams, Shelley Fried, Ahmed Raslan, Eric Halgren, Sydney […]


Continue.. Flexible, Scalable, High Channel Count Stereo-Electrode for Recording in the Human Brain

Mosaic chromosomal alterations in blood across ancestries via whole-genome sequencing

Kavli Affiliate: V. S. Ramachandran | Authors: Paul L. Auer, Yasminka A Jakubek, Ying Zhou, Adrienne M Stilp, Jason Bacon, Justin Wong, Braxton Mitchell, Joshua Lewis, Eric Boerwinkle, Ruth J.F. Loos, Michael Preuss, Kathleen Barnes, Nathan Pankratz, Myriam Fornage, Susan Redline, Bruce M. Psaty, Joshua C. Bis, Edwin Silverman, Michael Cho, Jeong Yun, Vasan Ramachandran, […]


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Novel inhibitors against COVID-19 main protease suppressed viral infection

Kavli Affiliate: V. S. Ramachandran | Authors: Vijayan Ramachandran, Yanyun Liu, Qianying He, Andrew Tang, Patrick Ronaldson, Dominik Schenten and Rui Chang | Summary: Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of COVID-19, can cause severe disease with high mortality rates, especially among older and vulnerable populations. Despite the recent success […]


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Transcriptomic cytoarchitecture reveals principles of human neocortex organization

Kavli Affiliate: Edward Callaway | Authors: Nikolas L. Jorstad, Jennie Close, Nelson Johansen, Anna Marie Yanny, Eliza R. Barkan, Kyle J. Travaglini, Darren Bertagnolli, Jazmin Campos, Tamara Casper, Kirsten Crichton, Nick Dee, Song-Lin Ding, Emily Gelfand, Jeff Goldy, Daniel Hirschstein, Matthew Kroll, Michael Kunst, Kanan Lathia, Brian Long, Naomi Martin, Delissa McMillen, Trangthanh Pham, Christine […]


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The efficacy of chemotherapy is limited by intratumoural senescent cells that persist through the upregulation of PD-L2

Kavli Affiliate: Jose Suarez Lopez | Authors: Selim Chaib, José Alberto López-Domínguez, Marta Lalinde, Neus Prats, Inés Marín, Kathleen Meyer, María Isabel Muñoz, Mònica Aguilera, Lidia Mateo, Camille Stephan-Otto Attolini, Susana Llanos, Marta Escorihuela, Sandra Pérez-Ramos, Fatima Al-Shahrour, Timothy P Cash, Tamara Tchkonia, James L Kirkland, Joaquín Arribas and Manuel Serrano | Summary: Abstract Anti-cancer […]


Continue.. The efficacy of chemotherapy is limited by intratumoural senescent cells that persist through the upregulation of PD-L2

The molecular genetic landscape of human brain size variation

Kavli Affiliate: Eric Courchesne | Authors: Jakob Seidlitz, Travis T. Mallard, Jacob W. Vogel, Younga H. Lee, Varun Warrier, Gareth Ball, Oskar Hansson, Leanna M. Hernandez, Ayan S. Mandal, Konrad Wagstyl, Michael V. Lombardo, Eric Courchesne, Joseph T. Glessner, Theodore D. Satterthwaite, Richard A.I. Bethlehem, Lifespan Brain Chart Consortium, Shinya Tasaki, Bernard Ng, Chris Gaiteri, […]


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Amygdalostriatal transition zone neurons encode sustained valence to direct conditioned behaviors

Kavli Affiliate: Kay Tye | Authors: Fergil Mills, Christopher R Lee, James R Howe, Hao Li, Shan Shao, Maria N Keisler, Mackenzie E Lemieux, Felix H Taschbach, Laurel R Keyes, Matilde R Borio, Hannah S Chen, Reesha R. Patel, Alexa L Gross, Jeremy Delahanty, Christian Cazares, Liezl Maree, Romy Wichmann, Talmo D Pereira, Marcus K […]


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Spike-phase coupling patterns reveal laminar identity in primate cortex

Kavli Affiliate: John Reynolds | Authors: Zachary W Davis, Nicholas M Dotson, Tom Franken, Lyle Muller and John Reynolds | Summary: Abstract The cortical column is one of the fundamental computational circuits in the brain. In order to understand the role neurons in different layers of this circuit play in cortical function it is necessary […]


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Localized APP pathology in the hippocampus is sufficient to result in progressive disorganization of the timing of neuronal firing patterns

Kavli Affiliate: Jill Leutgeb | Authors: Silvia Viana da Silva, Matthias G Haberl, Kshitij Gaur, Rina Patel, Gautam Narayan, Max Ledakis, Maylin L. Fu, Edward H. Koo, Jill K. Leutgeb and Stefan Leutgeb | Summary: Abstract Deficits in spatial navigation are among the early symptoms in Alzheimer’s disease patients, consistent with the hippocampal formation as […]


Continue.. Localized APP pathology in the hippocampus is sufficient to result in progressive disorganization of the timing of neuronal firing patterns

A conserved principle of glial organization in the paleocortex and neocortex

Kavli Affiliate: Terrence Sejnowski | Authors: Antonio Pinto-Duarte, Katherine Bogue, Terrence J Sejnowski and Shyam Srinivasan | Summary: Abstract The neocortex and paleocortex process sensory information and take part in higher cognitive tasks such as decision-making. The environment of the circuits within these regions is largely controlled by glial cells. Studies have shown that, across […]


Continue.. A conserved principle of glial organization in the paleocortex and neocortex