Heritability estimation of cognitive phenotypes in the ABCD Study using mixed models

Kavli Affiliate: Wesley Thompson, Anders Dale, Terry Jernigan | Authors: Diana M. Smith, Robert John Loughnan, Naomi P. Friedman, Pravesh Parekh, Oleksandr Frei, Wesley K. Thompson, Ole Andreassen, Michael Neale, Terry L. Jernigan and Anders Dale | Summary: Twin and family studies have historically aimed to partition phenotypic variance into components corresponding to additive genetic […]


Continue.. Heritability estimation of cognitive phenotypes in the ABCD Study using mixed models

Astrocyte glypican 5 regulates synapse maturation and stabilization

Kavli Affiliate: Nicola Allen | Authors: Alexandra P Bosworth, Minerva Contreras, Sammy Weiser Novak, Laura Sancho, Isabel H Salas, Uri Manor and Nicola J Allen | Summary: The maturation and stabilization of appropriate synaptic connections is a vital step in the development of neuronal circuits, however the molecular signals underlying these processes are not fully […]


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White matter and literacy: a dynamic system in flux

Kavli Affiliate: Terry Jernigan, Timothy Brown | Authors: Ethan Roy, Adam Richie-Halford, John Kruper, Manjari Narayan, David Bloom, Pierre Nedelec, Leo P. Sugrue, Andreas Rauschecker, Timothy T. Brown, Terry L. Jernigan, Bruce D. McCandliss, Ariel Rokem and Jason D. Yeatman | Summary: Cross-sectional studies have linked differences in white matter tissue properties to reading skills. […]


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Restructuring of olfactory representations in the fly brain around odor relationships in natural sources

Kavli Affiliate: Tatyana Sharpee | Authors: Jie-Yoon Yang, Thomas F O’Connell, Wei-Mien M Hsu, Matthew S Bauer, Kristina V. Dylla, Tatyana O Sharpee and Elizabeth J Hong | Summary: A core challenge of olfactory neuroscience is to understand how neural representations of odor are generated and progressively transformed across different layers of the olfactory circuit […]


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Construction of a 3D whole organism spatial atlas by joint modeling of multiple slices

Kavli Affiliate: Angela Wu | Authors: Gefei Wang, Jia Zhao, Yan Yan, Yang Wang, Angela Ruohao Wu and Can Yang | Summary: Spatial transcriptomics (ST) technologies are revolutionizing the way that researchers explore the spatial architecture of tissues. Currently, ST data analysis is often restricted to 2D space within a single tissue slice, limiting our […]


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The double-drift illusion biases the marmoset oculomotor system

Kavli Affiliate: John Reynolds | Authors: Nicholas M Dotson, Zachary W Davis, Jared M Salisbury, Stephanie E Palmer, Patrick Cavanagh and John Reynolds | Summary: Abstract The double-drift illusion has two unique characteristics: the error between the perceived and physical position of the stimulus grows over time, and saccades to the moving target land much […]


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Finemap-MiXeR: A variational Bayesian approach for genetic finemapping

Kavli Affiliate: Anders Dale | Authors: Bayram Cevdet Akdeniz, Oleksandr Frei, Alexey Shadrin, Dmitry Vetrov, Dmitry Kropotov, Anders Dale, Eivind Hovig and Ole Andreassen | Summary: Abstract Discoveries from genome-wide association studies often contain large clusters of highly correlated genetic variants, which makes them hard to interpret. In such cases, finemapping the underlying causal variants […]


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EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis

Kavli Affiliate: Jose Suarez Lopez | Authors: Sukanya Chakraborty, Aaqib M. Bhat, Insha Mushtaq, Haitao Luan, Achyuth Kalluchi, Sameer Mirza, Matthew D. Storck, Nagendra Chaturvedi, Jose Antonio Lopez-Guerreo, Antonio Llombart-Bosch, Isidro Machado, Jane L. Meza, Gargi Ghosal, Donald W. Coulter, Jordan M. Rowley, Vimla Band, Bhopal C. Mohapatra and Hamid Band | Summary: We previously […]


Continue.. EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis

Grapevine scion gene expression is driven by rootstock and environment interaction

Kavli Affiliate: Angela Wu | Authors: Zachary N Harris, Julia E Pratt, Laszlo G Kovacs, Laura L Klein, Misha T Kwasniewski, Jason P Londo, Angela Wu and Allison J Miller | Summary: BACKGROUND Grafting is a horticultural practice used widely across woody perennial crop species to fuse together the root and shoot system of two […]


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Low Rate Hippocampal Delay Period Activity Encodes Behavioral Experience

Kavli Affiliate: Jill Leutgeb | Authors: Markos Athanasiadis, Stefano Masserini, Li Yuan, Dustin Fetterhoff, Jill K Leutgeb, Stefan Leutgeb and Christian Leibold | Summary: Remembering what just happened is a crucial prerequisite to form long-term memories but also for establishing and maintaining working memory. So far there is no general agreement about cortical mechanisms that […]


Continue.. Low Rate Hippocampal Delay Period Activity Encodes Behavioral Experience