Kavli Affiliate: Angela Yu | Authors: Liang Liu, Angela M Yu, Xiuye Wang, Lindsey V. Soles, Yiling Chen, Yoseop Yoon, Kristianna S.K. Sarkan, Marielle Cárdenas Valdez, Johannes Linder, Ivan Marazzi, Zhaoxia Yu, Feng Qiao, Wei Li, Georg Seelig and Yongsheng Shi | Summary: JTE-607 is a small molecule compound with anti-inflammation and anti-cancer activities. Upon […]
Kavli Affiliate: Mark Ellisman | Authors: Varda Lev-Ram, Sakina Palida, Thomas J Deerinck, Eric A Bushong, Brandon H Toyoma, Alex Perez, Daniel B McClatchy, Denise R Prichard, Jeffrey N Savas, Mark H Ellisman, John Robert Yates III and Roger Y Tsien | Summary: Perineuronal nets (PNN), a specialized form of ECM, surround numerous neurons in […]
Kavli Affiliate: V. S. Ramachandran | Authors: Abhishek Gopal, Sartaj Ghuman, Navendu Page, Vivek Ramachandran and Rohit Naniwadekar | Summary: Oceanic islands, due to their evolutionary history and isolation, hold a disproportionately high proportion of endemic species. However, their evolutionary history also makes them vulnerable to extinctions, with most known extinctions occurring on islands. Plant-animal […]
Kavli Affiliate: Mark Ellisman | Authors: Tylor R Lewis, Sebastien Phan, Carson M Castillo, Keun-Young Kim, Kelsey Coppenrath, William Thomas, Ying Hao, Nikolai P Skiba, Marko E Horb, Mark H Ellisman and Vadim Y Arshavsky | Summary: The first steps of vision take place within a stack of tightly packed disc-shaped membranes, or “discs”, located […]
Kavli Affiliate: Anastasia Kiyonaga | Authors: Arielle Tambini, Jacob Miller, Luke Ehlert, Anastasia Kiyonaga and Mark D’Esposito | Summary: Influential views of systems memory consolidation posit that the hippocampus rapidly forms representations of specific events, while neocortical networks extract regularities across events, forming the basis of schemas and semantic knowledge. Neocortical extraction of schematic memory […]
Kavli Affiliate: Terrence Sejnowski | Authors: Yusi Chen, Huanqiu Zhang and Terrence J Sejnowski | Summary: We linked the temporal precision of neural encoding to the implementation of cognitive functions through predictive sequence learning. The hippocampus of rodents receives sequences of sensory inputs from the cortex during exploration and then encodes the sequences with millisecond […]
Kavli Affiliate: Jose Ricardo Suarez | Authors: Blanca Dies, Ana de Lucas-Rius, Laura Mendoza, Transito Garcia, Raul Fernandez, Jose Manuel Suarez, Fatima Milhano, Fernando Corrales, Natalia Redondo, Federica Pedrucci, Sara Zaldivar, Maria Angeles Jimenez, Maria Montoya and Juan Jose Garrido | Summary: SARS-CoV-2, the cause of the COVID19 pandemic, possesses eleven accessory proteins encoded in […]
Kavli Affiliate: Samuel Pfaff | Authors: Marito Hayashi, Miriam Gullo, Gokhan Senturk, Stefania Di Costanzo, Shinji C. Nagasaki, Ryoichiro Kageyama, Itaru Imayoshi, Martyn Goulding, Samuel L. Pfaff and Graziana Gatto | Summary: Innate and goal-directed movements require a high-degree of trunk and appendicular muscle coordination to preserve body stability while ensuring the correct execution of […]
Kavli Affiliate: Angela Wu | Authors: Xiaomeng Wan, Jiashun Xiao, Sindy Sing Ting Tam, Mingxuan Cai, Ryohichi Sugimura, Yang Wang, Xiang Wan, Zhixiang Lin, Angela Wu and Can Yang | Summary: The rapid emergence of spatial transcriptomics (ST) technologies are revolutionizing our under-standing of tissue spatial architecture and their biology. Current ST technologies based on […]
Kavli Affiliate: Dhakshin Ramanathan, Jyoti Mishra | Authors: M.F. Koloski, S. Hulyalkar, T. Tang, X. Wu, L. Fakhraei, S.A. Barnes, J. Mishra, D.S. Ramanathan | Summary: Abstract Single neuron correlates of reward value have been observed in brain regions along the cortico-striatal pathway including ventral striatum, orbital, and medial prefrontal cortex. Brain imaging studies in […]