Predictive Sequence Learning in the Hippocampal Formation

Kavli Affiliate: Terrence Sejnowski | Authors: Yusi Chen, Huanqiu Zhang and Terrence J Sejnowski | Summary: We linked the temporal precision of neural encoding to the implementation of cognitive functions through predictive sequence learning. The hippocampus of rodents receives sequences of sensory inputs from the cortex during exploration and then encodes the sequences with millisecond […]


Continue.. Predictive Sequence Learning in the Hippocampal Formation

SARS-CoV-2 accessory proteins involvement in inflammatory and profibrotic processes through IL11 signaling

Kavli Affiliate: Jose Ricardo Suarez | Authors: Blanca Dies, Ana de Lucas-Rius, Laura Mendoza, Transito Garcia, Raul Fernandez, Jose Manuel Suarez, Fatima Milhano, Fernando Corrales, Natalia Redondo, Federica Pedrucci, Sara Zaldivar, Maria Angeles Jimenez, Maria Montoya and Juan Jose Garrido | Summary: SARS-CoV-2, the cause of the COVID19 pandemic, possesses eleven accessory proteins encoded in […]


Continue.. SARS-CoV-2 accessory proteins involvement in inflammatory and profibrotic processes through IL11 signaling

A spinal synergy of excitatory and inhibitory neurons coordinates ipsilateral body movements

Kavli Affiliate: Samuel Pfaff | Authors: Marito Hayashi, Miriam Gullo, Gokhan Senturk, Stefania Di Costanzo, Shinji C. Nagasaki, Ryoichiro Kageyama, Itaru Imayoshi, Martyn Goulding, Samuel L. Pfaff and Graziana Gatto | Summary: Innate and goal-directed movements require a high-degree of trunk and appendicular muscle coordination to preserve body stability while ensuring the correct execution of […]


Continue.. A spinal synergy of excitatory and inhibitory neurons coordinates ipsilateral body movements

SpatialScope: A unified approach for integrating spatial and single-cell transcriptomics data using deep generative models

Kavli Affiliate: Angela Wu | Authors: Xiaomeng Wan, Jiashun Xiao, Sindy Sing Ting Tam, Mingxuan Cai, Ryohichi Sugimura, Yang Wang, Xiang Wan, Zhixiang Lin, Angela Wu and Can Yang | Summary: The rapid emergence of spatial transcriptomics (ST) technologies are revolutionizing our under-standing of tissue spatial architecture and their biology. Current ST technologies based on […]


Continue.. SpatialScope: A unified approach for integrating spatial and single-cell transcriptomics data using deep generative models

Cortico-Striatal Beta-Oscillations as a Marker of Learned Reward Value

Kavli Affiliate: Dhakshin Ramanathan, Jyoti Mishra | Authors: M.F. Koloski, S. Hulyalkar, T. Tang, X. Wu, L. Fakhraei, S.A. Barnes, J. Mishra, D.S. Ramanathan | Summary: Abstract Single neuron correlates of reward value have been observed in brain regions along the cortico-striatal pathway including ventral striatum, orbital, and medial prefrontal cortex. Brain imaging studies in […]


Continue.. Cortico-Striatal Beta-Oscillations as a Marker of Learned Reward Value

Heritability estimation of cognitive phenotypes in the ABCD Study using mixed models

Kavli Affiliate: Wesley Thompson, Anders Dale, Terry Jernigan | Authors: Diana M. Smith, Robert John Loughnan, Naomi P. Friedman, Pravesh Parekh, Oleksandr Frei, Wesley K. Thompson, Ole Andreassen, Michael Neale, Terry L. Jernigan and Anders Dale | Summary: Twin and family studies have historically aimed to partition phenotypic variance into components corresponding to additive genetic […]


Continue.. Heritability estimation of cognitive phenotypes in the ABCD Study using mixed models

Astrocyte glypican 5 regulates synapse maturation and stabilization

Kavli Affiliate: Nicola Allen | Authors: Alexandra P Bosworth, Minerva Contreras, Sammy Weiser Novak, Laura Sancho, Isabel H Salas, Uri Manor and Nicola J Allen | Summary: The maturation and stabilization of appropriate synaptic connections is a vital step in the development of neuronal circuits, however the molecular signals underlying these processes are not fully […]


Continue.. Astrocyte glypican 5 regulates synapse maturation and stabilization

White matter and literacy: a dynamic system in flux

Kavli Affiliate: Terry Jernigan, Timothy Brown | Authors: Ethan Roy, Adam Richie-Halford, John Kruper, Manjari Narayan, David Bloom, Pierre Nedelec, Leo P. Sugrue, Andreas Rauschecker, Timothy T. Brown, Terry L. Jernigan, Bruce D. McCandliss, Ariel Rokem and Jason D. Yeatman | Summary: Cross-sectional studies have linked differences in white matter tissue properties to reading skills. […]


Continue.. White matter and literacy: a dynamic system in flux

Restructuring of olfactory representations in the fly brain around odor relationships in natural sources

Kavli Affiliate: Tatyana Sharpee | Authors: Jie-Yoon Yang, Thomas F O’Connell, Wei-Mien M Hsu, Matthew S Bauer, Kristina V. Dylla, Tatyana O Sharpee and Elizabeth J Hong | Summary: A core challenge of olfactory neuroscience is to understand how neural representations of odor are generated and progressively transformed across different layers of the olfactory circuit […]


Continue.. Restructuring of olfactory representations in the fly brain around odor relationships in natural sources

Construction of a 3D whole organism spatial atlas by joint modeling of multiple slices

Kavli Affiliate: Angela Wu | Authors: Gefei Wang, Jia Zhao, Yan Yan, Yang Wang, Angela Ruohao Wu and Can Yang | Summary: Spatial transcriptomics (ST) technologies are revolutionizing the way that researchers explore the spatial architecture of tissues. Currently, ST data analysis is often restricted to 2D space within a single tissue slice, limiting our […]


Continue.. Construction of a 3D whole organism spatial atlas by joint modeling of multiple slices