A spinal synergy of excitatory and inhibitory neurons coordinates ipsilateral body movements

Kavli Affiliate: Samuel Pfaff | Authors: Marito Hayashi, Miriam Gullo, Gokhan Senturk, Stefania Di Costanzo, Shinji C. Nagasaki, Ryoichiro Kageyama, Itaru Imayoshi, Martyn Goulding, Samuel L. Pfaff and Graziana Gatto | Summary: Innate and goal-directed movements require a high-degree of trunk and appendicular muscle coordination to preserve body stability while ensuring the correct execution of […]


Continue.. A spinal synergy of excitatory and inhibitory neurons coordinates ipsilateral body movements

SpatialScope: A unified approach for integrating spatial and single-cell transcriptomics data using deep generative models

Kavli Affiliate: Angela Wu | Authors: Xiaomeng Wan, Jiashun Xiao, Sindy Sing Ting Tam, Mingxuan Cai, Ryohichi Sugimura, Yang Wang, Xiang Wan, Zhixiang Lin, Angela Wu and Can Yang | Summary: The rapid emergence of spatial transcriptomics (ST) technologies are revolutionizing our under-standing of tissue spatial architecture and their biology. Current ST technologies based on […]


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Cortico-Striatal Beta-Oscillations as a Marker of Learned Reward Value

Kavli Affiliate: Dhakshin Ramanathan, Jyoti Mishra | Authors: M.F. Koloski, S. Hulyalkar, T. Tang, X. Wu, L. Fakhraei, S.A. Barnes, J. Mishra, D.S. Ramanathan | Summary: Abstract Single neuron correlates of reward value have been observed in brain regions along the cortico-striatal pathway including ventral striatum, orbital, and medial prefrontal cortex. Brain imaging studies in […]


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Heritability estimation of cognitive phenotypes in the ABCD Study using mixed models

Kavli Affiliate: Wesley Thompson, Anders Dale, Terry Jernigan | Authors: Diana M. Smith, Robert John Loughnan, Naomi P. Friedman, Pravesh Parekh, Oleksandr Frei, Wesley K. Thompson, Ole Andreassen, Michael Neale, Terry L. Jernigan and Anders Dale | Summary: Twin and family studies have historically aimed to partition phenotypic variance into components corresponding to additive genetic […]


Continue.. Heritability estimation of cognitive phenotypes in the ABCD Study using mixed models

Astrocyte glypican 5 regulates synapse maturation and stabilization

Kavli Affiliate: Nicola Allen | Authors: Alexandra P Bosworth, Minerva Contreras, Sammy Weiser Novak, Laura Sancho, Isabel H Salas, Uri Manor and Nicola J Allen | Summary: The maturation and stabilization of appropriate synaptic connections is a vital step in the development of neuronal circuits, however the molecular signals underlying these processes are not fully […]


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White matter and literacy: a dynamic system in flux

Kavli Affiliate: Terry Jernigan, Timothy Brown | Authors: Ethan Roy, Adam Richie-Halford, John Kruper, Manjari Narayan, David Bloom, Pierre Nedelec, Leo P. Sugrue, Andreas Rauschecker, Timothy T. Brown, Terry L. Jernigan, Bruce D. McCandliss, Ariel Rokem and Jason D. Yeatman | Summary: Cross-sectional studies have linked differences in white matter tissue properties to reading skills. […]


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Restructuring of olfactory representations in the fly brain around odor relationships in natural sources

Kavli Affiliate: Tatyana Sharpee | Authors: Jie-Yoon Yang, Thomas F O’Connell, Wei-Mien M Hsu, Matthew S Bauer, Kristina V. Dylla, Tatyana O Sharpee and Elizabeth J Hong | Summary: A core challenge of olfactory neuroscience is to understand how neural representations of odor are generated and progressively transformed across different layers of the olfactory circuit […]


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Construction of a 3D whole organism spatial atlas by joint modeling of multiple slices

Kavli Affiliate: Angela Wu | Authors: Gefei Wang, Jia Zhao, Yan Yan, Yang Wang, Angela Ruohao Wu and Can Yang | Summary: Spatial transcriptomics (ST) technologies are revolutionizing the way that researchers explore the spatial architecture of tissues. Currently, ST data analysis is often restricted to 2D space within a single tissue slice, limiting our […]


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The double-drift illusion biases the marmoset oculomotor system

Kavli Affiliate: John Reynolds | Authors: Nicholas M Dotson, Zachary W Davis, Jared M Salisbury, Stephanie E Palmer, Patrick Cavanagh and John Reynolds | Summary: Abstract The double-drift illusion has two unique characteristics: the error between the perceived and physical position of the stimulus grows over time, and saccades to the moving target land much […]


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Finemap-MiXeR: A variational Bayesian approach for genetic finemapping

Kavli Affiliate: Anders Dale | Authors: Bayram Cevdet Akdeniz, Oleksandr Frei, Alexey Shadrin, Dmitry Vetrov, Dmitry Kropotov, Anders Dale, Eivind Hovig and Ole Andreassen | Summary: Abstract Discoveries from genome-wide association studies often contain large clusters of highly correlated genetic variants, which makes them hard to interpret. In such cases, finemapping the underlying causal variants […]


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