Myomatrix arrays for high-definition muscle recording

Kavli Affiliate: Eiman Azim, Rui Costa | Authors: Bryce Chung, Muneeb Zia, Kyle A. Thomas, Jonathan A. Michaels, Amanda Jacob, Andrea Pack, Matthew J. Williams, Kailash Nagapudi, Lay Heng Teng, Eduardo Arrambide, Logan Ouellette, Nicole Oey, Rhuna Gibbs, Philip Anschutz, Jiaao Lu, Yu Wu, Mehrdad Kashefi, Tomomichi Oya, Rhonda Kersten, Alice C Mosberger, Sean O`Connell, […]


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Machine assisted annotation in neuroanatomy

Kavli Affiliate: David Kleinfeld | Authors: Kui Qian, David Kleinfeld, Beth Friedman and Yoav Freund | Summary: One routine and necessary, yet time-consuming task in neuroanatomy is the annotation of labeled cells relative to the background. Currently, staining and imaging techniques enable the marking of specific cell groups with fluorescent dyes. Modern high throughput scanning […]


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Categorization dynamically alters representations in human visual cortex

Kavli Affiliate: John Serences | Authors: Margaret M Henderson, John T Serences and Nuttida Rungratsameetaweemana | Summary: Everyday visual search tasks require objects to be categorized according to behavioral goals. For example, when searching for an apple at the supermarket, one might first find the Granny Smith apples by separating all visible apples into the […]


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Laws for Glia Organization Conserved Across Mammals

Kavli Affiliate: Terrence Sejnowski | Authors: Antonio Pinto-Duarte, Katharine Bogue, Terrence J. Sejnowski and Shyam Srinivasan | Summary: The organizational principles of glia remain largely unknown despite their vital role in nervous system function. Previous work has shown that the number of glia per unit volume of neocortex is constant across mammalian species. We hypothesize […]


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Cristae formation is a mechanical buckling event controlled by the inner membrane lipidome

Kavli Affiliate: Mark Ellisman | Authors: Kailash Venkatraman, Christopher T Lee, Guadalupe C. Garcia, Arijit Mahapatra, Guy Perkins, Keun-Young Kim, Hilda Amalia Pasolli, Sebastien Phan, Jennifer Lippincott-Schwartz, Mark Ellisman, Padmini Rangamani and Itay Budin | Summary: Cristae are high curvature structures in the inner mitochondrial membrane (IMM) that are crucial for ATP production. While cristae-shaping […]


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Spatiotemporal development of growth and death zones in expanding bacterial colonies driven by emergent nutrient dynamics

Kavli Affiliate: David Kleinfeld | Authors: Harish Kannan, Paul Sun, Tolga Çağlar, Pantong Yao, Brian R Taylor, Kinshuk Sahu, Daotong Ge, Matteo Mori, Mya Warren, David Kleinfeld, JiaJia Dong, Bo Li and Terence Hwa | Summary: Bacterial colony growth on hard agar is commonplace in microbiology; yet, what occurs inside a growing colony is complex […]


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Beyond Lux: Methods for Species and Photoreceptor-Specific Quantification of Ambient Light for Mammals

Kavli Affiliate: Timothy Brown | Authors: Richard J McDowell, Altug Didikoglu, Tom Woelders, Mazie J Gatt, Roelof A. Hut, Timothy M Brown and Robert J Lucas | Summary: Background Light is a key environmental regulator of physiology and behaviour. Mistimed or insufficient light disrupts circadian rhythms and is associated with impaired health and well-being across […]


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Caloric restriction promotes beta cell longevity and delays aging and senescence by enhancing cell identity and homeostasis mechanisms.

Kavli Affiliate: Mark Ellisman | Authors: Cristiane dos Santos, Shristi Shrestha, Matthew A Cottam, Guy Perkins, Varda Lev-Ram, Birbickram Roy, Christopher Acree, Keun-Young Kim, Thomas Deerinck, Melanie Cutler, Danielle Dean, Jean Philippe Cartailler, Patrick E MacDonald, Martin W Hetzer, Mark H Ellisman and Rafael Arrojo e Drigo | Summary: Caloric restriction (CR) extends organismal lifespan […]


Continue.. Caloric restriction promotes beta cell longevity and delays aging and senescence by enhancing cell identity and homeostasis mechanisms.

Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study

Kavli Affiliate: Anders Dale | Authors: Elleke Tissink, Alexey A Shadrin, Dennis van der Meer, Nadine Parker, Guy Hindley, Daniel Roelfs, Oleksandr Frei, Chun Chieh Fan, Mats Nagel, Terje Naerland, Magdalena Budisteanu, Srdjan Djurovic, Lars T. Westlye, Martijn van den Heuvel, Danielle Posthuma, Tobias Kaufmann, Anders M. Dale and Ole Andreassen | Summary: Genetic pleiotropy […]


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Estimating the Total Variance Explained by Whole-Brain Imaging for Zero-inflated Outcomes

Kavli Affiliate: Wesley Thompson | Authors: Junting Ren, Robert John Loughnan, Bohan Xu, Wesley K. Thompson and Chun Chieh Fan | Summary: Zero-inflated outcomes are very common in behavioral data, particularly for responses to psychological questionnaires. Modeling these challenging distributions is further exacerbated by the absence of established statistical models capable of characterizing total signals […]


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