A partnership of the lipid scramblase XK and of the lipid transfer protein VPS13A at the plasma membrane

Kavli Affiliate: Pietro DeCamilli | Authors: Andrés Guillén Samander, Yumei Wu, S. Sebastian Pineda, Francisco J. García, Julia N. Eisen, Marianna Leonzino, Berrak Uğur, Manolis Kellis, Myriam Heiman and Pietro De Camilli | Summary: Chorea-acanthocytosis and McLeod syndrome are diseases with shared clinical manifestations caused by mutations in VPS13A and XK, respectively. Key features of […]


Continue.. A partnership of the lipid scramblase XK and of the lipid transfer protein VPS13A at the plasma membrane

Mesoscopic oblique plane microscopy (Meso-OPM) – enabling large-scale 4D isotropic cellular resolution imaging with a diffractive light sheet

Kavli Affiliate: Patrick Kanold | Authors: Wenjun Shao, Minzi Chang, Kevin Emmerich, Patrick O Kanold, Jeff S Mumm and Ji Yi | Summary: Fundamental understanding of large-scale dynamic connectivity within a living organism requires volumetric imaging over a large field of view (FOV) at biologically relevant speed and resolution. However, most microscopy methods make trade-offs […]


Continue.. Mesoscopic oblique plane microscopy (Meso-OPM) – enabling large-scale 4D isotropic cellular resolution imaging with a diffractive light sheet

Mesoscopic oblique plane microscopy (Meso-OPM) with a diffractive light sheet- enabling large-scale 4D cellular resolution imaging

Kavli Affiliate: Patrick Kanold | Authors: Wenjun Shao, Minzi Chang, Kevin Emmerich, Patrick O Kanold, Jeff S Mumm and Ji Yi | Summary: Abstract Fundamental understanding of large-scale dynamic connectivity within a living organism requires volumetric imaging over a large field of view (FOV) at biologically relevant speed and resolution. However, most microscopy methods make […]


Continue.. Mesoscopic oblique plane microscopy (Meso-OPM) with a diffractive light sheet- enabling large-scale 4D cellular resolution imaging

Social Learning of a Spatial Task by Observation Alone

Kavli Affiliate: Clifford Kentros | Authors: Thomas Doublet, Mona Nosrati and Clifford G. Kentros | Summary: Interactions between conspecifics are central to the acquisition of useful memories in the real world. Observational learning, i.e., learning a task by observing the success or failure of others, has been reported in many species, including rodents. However, previous […]


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The Neurodata Without Borders ecosystem for neurophysiological data science

Kavli Affiliate: Kristofer Bouchard, Loren Frank | Authors: Oliver Rübel, Andrew Tritt, Ryan Ly, Benjamin K. Dichter, Satrajit Ghosh, Lawrence Niu, Ivan Soltesz, Karel Svoboda, Loren Frank and Kristofer E. Bouchard | Summary: The neurophysiology of cells and tissues are monitored electrophysiologically and optically in diverse experiments and species, ranging from flies to humans. Understanding […]


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Sensory readout accounts for adaptation

Kavli Affiliate: John Serences | Authors: Timothy C. Sheehan and John T. Serences | Summary: Sensory responses and behavior are strongly shaped by stimulus history. For instance, perceptual reports are sometimes biased towards previously viewed stimuli (serial dependence). While behavioral studies have pointed to both perceptual and post-perceptual origins of this phenomenon, neural data that […]


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Pangenomics provides insights into the role of synanthropy in barn swallow evolution

Kavli Affiliate: Erich Jarvis | Authors: Simona Secomandi, Guido Roberto Gallo, Marcella Sozzoni, Alessio Iannucci, Elena Galati, Linelle Abueg, Jennifer Balacco, Manuela Caprioli, William Chow, Claudio Ciofi, Joanna Collins, Olivier Fedrigo, Luca Ferretti, Arkarachai Fungtammasan, Bettina Haase, Kerstin Howe, Woori Kwak, Gianluca Lombardo, Patrick Masterson, Graziella Messina, Anders Pape Møller, Jacquelyn Mountcastle, Timothy A. Mousseau, […]


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Gfastats: conversion, evaluation and manipulation of genome sequences using assembly graphs

Kavli Affiliate: Erich Jarvis | Authors: Giulio Formenti, Linelle Abueg, Angelo Brajuka, Nadolina Brajuka, Cristo Gallardo, Alice Giani, Olivier Fedrigo and Erich D. Jarvis | Summary: Motivation With the current pace at which reference genomes are being produced, the availability of tools that can reliably and efficiently generate genome assembly summary statistics has become critical. […]


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Two modes of mid-frontal theta suggest a role in conflict and error processing

Kavli Affiliate: Adam Aron | Authors: Vignesh Muralidharan, Adam R Aron, Micheal X Cohen and Robert Schmidt | Summary: Mid-frontal theta is well-known to be involved in conflict and error-processing. In paradigms known to evoke response conflict, the temporal sequence of events leading up to conflict or error resolution and theta’s involvement in such scenarios […]


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CryoET Reveals Organelle Phenotypes in Huntington Disease Patient iPSC-Derived and Mouse Primary Neurons

Kavli Affiliate: William Mobley | Authors: Gong-Her Wu, Charlene Smith-Geater, Jesus G. Galaz-Montoya, Yingli Gu, Sanket R Gupte, Ranen Aviner, Patrick G. Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q. Wang, Nicolette Geller, Cristina Danita, Lydia-Marie Joubert, Michael F. Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M. Thompson and Wah Chiu | Summary: […]


Continue.. CryoET Reveals Organelle Phenotypes in Huntington Disease Patient iPSC-Derived and Mouse Primary Neurons