Genomic, genetic and phylogenetic evidence for a new falcon species using chromosome-level genome assembly of the gyrfalcon and population genomics

Posted by klaurent Rockefeller

Kavli Affiliate: Erich Jarvis | Authors: Farooq Omar Al-Ajli, Giulio Formenti, Olivier Fedrigo, Alan Tracey, Ying Sims, Kerstin Howe, Ikdam Karkhi, Asmaa Althani, Erich Jarvis, Sadequr Rahman and Qasim Ayub | Summary: The taxonomic classification of a falcon population found in the Altai region in Asia has been heavily debated for two centuries and previous […]


Continue.. Genomic, genetic and phylogenetic evidence for a new falcon species using chromosome-level genome assembly of the gyrfalcon and population genomics

Neuronal birthdate reveals topography in a vestibular brainstem circuit for gaze stabilization

Posted by klaurent Columbia

Kavli Affiliate: Elizabeth Hillman | Authors: Dena Goldblatt, Stephanie Huang, Marie R. Greaney, Kyla R. Hamling, Venkatakaushik Voleti, Citlali Perez-Campos, Kripa B. Patel, Wenze Li, Elizabeth M. C. Hillman, Martha W. Bagnall and David Schoppik | Summary: Abstract Across the nervous system, neurons with similar attributes are topographically organized. This topography reflects developmental pressures. Oddly, […]


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Semaphorin7A patterns neural circuitry in the lateral line of the zebrafish

Posted by klaurent Rockefeller

Kavli Affiliate: A. James Hudspeth | Authors: Agnik Dasgupta, Caleb C. Reagor, Sang Peter Paik, Lauren M Snow, Adrian Jacobo and Albert Hudspeth | Summary: In a developing nervous system, axonal arbors often undergo complex rearrangements before neural circuits attain their final innervation topology. In the lateral line sensory system of the zebrafish, developing sensory […]


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MISPEL: A deep learning approach for harmonizing multi-scanner matched neuroimaging data

Posted by klaurent Hopkins

Kavli Affiliate: Ciprian Crainiceanu | Authors: Mahbaneh Eshaghzadeh Torbati, Davneet S Minhas, Charles M Laymon, Pauline Maillard, James D Wilson, Chang-Le Chen, Ciprian M Crainiceanu, Charles S DeCarli, Seong Jae Hwang and Dana L Tudorascu | Summary: Abstract Large-scale data obtained from aggregation of already collected multi-site neuroimaging datasets has been brought benefits such as […]


Continue.. MISPEL: A deep learning approach for harmonizing multi-scanner matched neuroimaging data

A quick and cost-effective method for DNA-free total RNA isolation using magnetic silica beads

Posted by klaurent Columbia

Kavli Affiliate: Aniruddha Das | Authors: Aniruddha Das, Debojyoti Das, Arundhati Das and Amaresh Chandra Panda | Summary: Current RNA purification methods widely use silica-based columns that allow quick isolation of high-quality and good quantities of RNA. However, the major limitations include high cost, the requirement of different kits for small RNA isolation, genomic DNA […]


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Standing genetic variation and chromosome differences drove rapid ecotype formation in a major malaria mosquito

Posted by klaurent Columbia

Kavli Affiliate: Scott Small | Authors: Scott T. Small, Carlo Costantini, N’Fale Sagnon, Moussa W. Guelbeogo, Scott J. Emrich, Andrew D. Kern, Michael C. Fontaine and Nora J. Besansky | Summary: Species distributed across heterogeneous environments often evolve locally adapted ecotypes, but understanding of the genetic mechanisms involved in their formation and maintenance in the […]


Continue.. Standing genetic variation and chromosome differences drove rapid ecotype formation in a major malaria mosquito

Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing

Posted by klaurent Rockefeller

Kavli Affiliate: Robert B. Darnell | Authors: Leena Ali Ibrahim, Brie Wamsley, Norah Alghamdi, Nusrath Yusuf, Elaine Sevier, Ariel Hairston, Mia Sherer, Xavier Hubert Jaglin, Qing Xu, Lijua Gao, Alireza Khodadadi-Jamayran, Emilia Favuzzi, Yuan Yuan, Jordane Dimidschstein, Robert Darnell and Gordon Fishell | Summary: Somatostatin interneurons are the earliest born population of cortical inhibitory cells. […]


Continue.. Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing

Standing genetic variation and chromosome differences drove rapid ecotype formation in a major malaria vector

Posted by klaurent Columbia

Kavli Affiliate: Scott Small | Authors: Scott T Small, Carlo Costantini, N’Fale Sagnon, Moussa W Guelbeogo, Scott J Emrich, Andrew D Kern, Michael C Fontaine and Nora J Besansky | Summary: Abstract Local adaptation results in the formation of ecotypes–conspecific groups with heritable differences that increase fitness to distinct environments. The adaptive significance of ecotypes […]


Continue.. Standing genetic variation and chromosome differences drove rapid ecotype formation in a major malaria vector

The Clustered Gamma Protocadherin Pcdhγc4 Isoform Regulates Cortical Interneuron Programmed Cell Death in the Mouse Cortex

Posted by klaurent UCSF

Kavli Affiliate: Arturo Alvarez-Buylla, Andrea Hasenstaub, Michael Stryker | Authors: Walter R Mancia Leon, David M Steffen, Fiona Dale-Huang, Benjamin Rakela, Arnar Breevoort, Ricardo Romero-Rodriguez, Andrea R Hasenstaub, Michael P Stryker, Joshua A Weiner and Arturo Alvarez-Buylla | Summary: Cortical function critically depends on inhibitory/excitatory balance. Cortical inhibitory interneurons (cINs) are born in the ventral […]


Continue.. The Clustered Gamma Protocadherin Pcdhγc4 Isoform Regulates Cortical Interneuron Programmed Cell Death in the Mouse Cortex

Construction of a 3D whole organism spatial atlas by joint modeling of multiple slices

Posted by klaurent UCSD / Salk

Kavli Affiliate: Angela Wu | Authors: Gefei Wang, Jia Zhao, Yan Yan, Yang Wang, Angela Ruohao Wu and Can Yang | Summary: Spatial transcriptomics (ST) technologies are revolutionizing the way that researchers explore the spatial architecture of tissues. Currently, ST data analysis is often restricted to 2D space within a single tissue slice, limiting our […]


Continue.. Construction of a 3D whole organism spatial atlas by joint modeling of multiple slices