A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila

Kavli Affiliate: Richard Axel | Authors: Moise Bonheur, Kurtis J. Swartz, Melissa G. Metcalf, Anna Zhukovskaya, Avirut Mehta, Kristin E. Connors, Julia G. Barasch, Xinke Wen, Andrew R. Jamieson, Kelsey C. Martin, Richard Axel and Daisuke Hattori | Summary: Neural activity is modulated over different timescales encompassing sub-seconds to days reflecting changes in external environment, […]


Continue.. A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila

Perirhinal Cortex Learns A Predictive Map of The Task Environment

Kavli Affiliate: Stefano Fusi | Authors: David G. Lee, Caroline A. McLachlan, Ramon Nogueira, Osung Kwon, Alanna E. Carey, Garrett House, Gavin D. Lagani, Danielle LaMay, Stefano Fusi and Jerry L. Chen | Summary: Goal-directed tasks involve acquiring an internal model, known as a predictive map, of relevant stimuli and associated outcomes to guide behavior. […]


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A brain atlas of the camouflaging dwarf cuttlefish, Sepia bandensis

Kavli Affiliate: Richard Axel | Authors: Tessa G. Montague, Isabelle J. Rieth, Sabrina Gjerswold-Selleck, Daniella Garcia-Rosales, Sukanya Aneja, Dana Elkis, Nanyan Zhu, Sabrina Kentis, Frederick A. Rubino, Adriana Nemes, Katherine Wang, Luke A. Hammond, Roselis Emiliano, Rebecca A. Ober, Jia Guo and Richard Axel | Summary: The coleoid cephalopods (cuttlefish, octopus, and squid) are a […]


Continue.. A brain atlas of the camouflaging dwarf cuttlefish, Sepia bandensis

Lightning Pose: improved animal pose estimation via semi-supervised learning, Bayesian ensembling, and cloud-native open-source tools

Kavli Affiliate: Liam Paninski, Nathaniel Sawtell | Authors: Dan Biderman, Matthew R Whiteway, Cole Hurwitz, Nicholas R Greenspan, Robert S Lee, Ankit Vishnubhotla, Michael Schartner, Julia M Huntenburg, Anup Khanal, Guido T Meijer, Jean-Paul Noel, Alejandro Pan-Vazquez, Karolina Z Socha, Anne E Urai, The International Brain Laboratory, Richard Warren, Dillon Noone, Federico Pedraja, John Cunningham, […]


Continue.. Lightning Pose: improved animal pose estimation via semi-supervised learning, Bayesian ensembling, and cloud-native open-source tools

Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons

Kavli Affiliate: Franck Polleux | Authors: Daniel M Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Emiliano Zamponi, Natalie J Park, Victoria L Hewitt, David Zhang, Kevin C Gonzalez, Erik Bloss, Franck Polleux and Tommy L Lewis, Jr. | Summary: Neuronal mitochondria play important roles beyond ATP generation, including Ca2+ uptake, and therefore have instructive roles […]


Continue.. Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons

Leveraging vision to understand curiosity

Kavli Affiliate: Jacqueline Gottlieb | Authors: Michael Cohanpour, Mariam Aly and Jacqueline Gottlieb | Summary: Humans are immensely curious and motivated to reduce uncertainty. Inspired by studies of sensory uncertainty, we hypothesized that visual areas provide multivariate representations of uncertainty, which are read out by higher-order areas that encode confidence and, ultimately, translated into curiosity. […]


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Organization and Plasticity of Inhibition in Hippocampal Recurrent Circuits

Kavli Affiliate: Attila Losonczy | Authors: Bert Vancura, Tristan Geiller and Attila Losonczy | Summary: Excitatory-inhibitory interactions structure recurrent network dynamics for efficient cortical computations. In the CA3 area of the hippocampus, recurrent circuit dynamics, including experience-induced plasticity at excitatory synapses, are thought to play a key role in episodic memory encoding and consolidation via […]


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Robust Online Multiband Drift Estimation in Electrophysiology Data

Kavli Affiliate: Liam Paninski | Authors: Charlie Windolf, Angelique C Paulk, Yoav Kfir, Eric Trautmann, Samuel Garcia, Domokos Meszéna, William Muñoz, Irene Caprara, Mohsen Jamali, Julien C Boussard, Ziv M Williams, Sydney S Cash, Liam Paninski and Erdem Varol | Summary: High-density electrophysiology probes have opened new possibilities for systems neuroscience in human and non-human […]


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Human synaptic neoteny requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition

Kavli Affiliate: Franck Polleux | Authors: Baptiste Libe-Philippot, Ryohei Iwata, Aleksandra J Recupero, Keimpe Wierda, Martyna Ditkowska, Vaiva Gaspariunaite, Ben Vermaercke, Eugenie Peze-Heidsieck, Daan Remans, Cecile Charrier, Franck Polleux and Pierre Vanderhaeghen | Summary: Human-specific (HS) genes are potential drivers of brain evolution, but their impact on human neuron development and disease remains unclear. Here […]


Continue.. Human synaptic neoteny requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition

A frontosensory circuit for visual context processing is synchronous in the theta/alpha band

Kavli Affiliate: Darcy Peterka | Authors: Georgia Bastos, Jacob T Holmes, Jordan M Ross, Anna M Rader, Connor G Gallimore, Darcy S Peterka and Jordan P Hamm | Summary: Visual processing is strongly influenced by context. Stimuli that deviate from contextual regularities elicit augmented responses in primary visual cortex (V1). These heightened responses, known as […]


Continue.. A frontosensory circuit for visual context processing is synchronous in the theta/alpha band