Nonlinear waves at the free surface of flexible mechanical metamaterials

Kavli Affiliate: Katia Bertoldi | First 5 Authors: Bolei Deng, Hang Shu, Jian Li, Chengyang Mo, Jordan R. Raney | Summary: In this letter we investigate the propagation of nonlinear pulses along the free surface of flexible metamaterials based on the rotating squares mechanism. While these metamaterials have previously been shown to support the propagation […]


Continue.. Nonlinear waves at the free surface of flexible mechanical metamaterials

Nonlinear waves at the free surface of flexible mechanical metamaterials

Kavli Affiliate: Katia Bertoldi | First 5 Authors: Bolei Deng, Hang Shu, Jian Li, Chengyang Mo, Jordan R. Raney | Summary: In this letter we investigate the propagation of nonlinear pulses along the free surface of flexible metamaterials based on the rotating squares mechanism. While these metamaterials have previously been shown to support the propagation […]


Continue.. Nonlinear waves at the free surface of flexible mechanical metamaterials

Ultralight and ultra-stiff nano-cardboard panels: mechanical analysis, characterization, and design principles

Kavli Affiliate: Katia Bertoldi | First 5 Authors: Jong-hyoung Kim, Lishuai Jin, Benjamin C. Schafer, Quan Jiao, Katia Bertoldi | Summary: We introduce a class of ultra-light and ultra-stiff sandwich panels designed for use in photophoretic levitation applications and investigate their mechanical behavior using both computational analyses and micro-mechanical testing. The sandwich panels consist of […]


Continue.. Ultralight and ultra-stiff nano-cardboard panels: mechanical analysis, characterization, and design principles

The physical basis of self-organization of the mammalian oocyte spindle

Kavli Affiliate: Daniel J. Needleman | First 5 Authors: Colm P Kelleher, Daniel J Needleman, , , | Summary: To prepare gametes with the appropriate number of chromosomes, mammalian oocytes undergo two sequential cell divisions. During each division, a large, long-lived, microtubule-based organelle called the meiotic spindle assembles around condensed chromosomes. Although meiotic spindles have […]


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Long-Range Repulsion Between Chromosomes in Mammalian Oocyte Spindles

Kavli Affiliate: Daniel J. Needleman | First 5 Authors: Colm P Kelleher, Yash Rana, Daniel J Needleman, , | Summary: During eukaryotic cell division, a microtubule-based structure called the spindle exerts forces on chromosomes, thereby organizing and segregating them Extensive work demonstrates that the forces acting parallel to the spindle axis, including those responsible for […]


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Personalized Dose Guidance using Safe Bayesian Optimization

Kavli Affiliate: Francis J. Doyle | First 5 Authors: Dinesh Krishnamoorthy, Francis J. Doyle III, , , | Summary: This work considers the problem of personalized dose guidance using Bayesian optimization that learns the optimum drug dose tailored to each individual, thus improving therapeutic outcomes. Safe learning using interior point method ensures patient safety with […]


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Fractal landscape dynamics in dense emulsions and stock prices

Kavli Affiliate: Vinothan N. Manoharan | First 5 Authors: Clary Rodriguez-Cruz, Mehdi Molaei, Amruthesh Thirumalaiswamy, Klebert Feitosa, Vinothan N. Manoharan | Summary: Many soft and biological materials display so-called ‘soft glassy’ dynamics; their constituents undergo anomalous random motion and intermittent cooperative rearrangements. Stock prices show qualitatively similar dynamics, whose origins also remain poorly understood. Recent […]


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Experimental observations of fractal landscape dynamics in a dense emulsion

Kavli Affiliate: Vinothan N. Manoharan | First 5 Authors: Clary Rodriguez-Cruz, Mehdi Molaei, Amruthesh Thirumalaiswamy, Klebert Feitosa, Vinothan N. Manoharan | Summary: Many soft and biological materials display so-called ‘soft glassy’ dynamics; their constituents undergo anomalous random motions and complex cooperative rearrangements. A recent simulation model of one soft glassy material, a coarsening foam, suggested […]


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Structure and dynamics of motor-driven microtubule bundles

Kavli Affiliate: Daniel J. Needleman | First 5 Authors: Bezia Lemma, Linnea Lemma, Stephanie C. Ems-McClung, Claire E. Walczak, Zvonimir Dogic | Summary: Connecting the large-scale emergent behaviors of active materials to the microscopic properties of their constituents is a challenge due to a lack of data on the multiscale dynamics and structure of such […]


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Conditional Probability as Found in Nature: Facilitated Diffusion

Kavli Affiliate: Ariel Amir | First 5 Authors: Ori Hachmo, Ariel Amir, , , | Summary: Transcription Factors (TFs) are proteins that regulate gene expression. The regulation mechanism is via the binding of a TF to a specific part of the gene associated with it, the TF’s target. The target of a specific TF corresponds […]


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