Kavli Affiliate: Changhuei Yang| First 5 Authors: Ling Liao, Ling Liao, , , | Summary:Spatial transcriptomics (ST) enables simultaneous mapping of tissue morphology and spatially resolved gene expression, offering unique opportunities to study tumor microenvironment heterogeneity. Here, we introduce a computational framework that predicts spatial pathway activity directly from hematoxylin-and-eosin-stained histology images at microscale resolution […]
Continue.. Digital Modeling of Spatial Pathway Activity from Histology Reveals Tumor Microenvironment Heterogeneity