Digital Modeling of Spatial Pathway Activity from Histology Reveals Tumor Microenvironment Heterogeneity

Kavli Affiliate: Changhuei Yang| First 5 Authors: Ling Liao, Ling Liao, , , | Summary:Spatial transcriptomics (ST) enables simultaneous mapping of tissue morphology and spatially resolved gene expression, offering unique opportunities to study tumor microenvironment heterogeneity. Here, we introduce a computational framework that predicts spatial pathway activity directly from hematoxylin-and-eosin-stained histology images at microscale resolution […]


Continue.. Digital Modeling of Spatial Pathway Activity from Histology Reveals Tumor Microenvironment Heterogeneity

Blur2Sharp: Human Novel Pose and View Synthesis with Generative Prior Refinement

Kavli Affiliate: N. C. Yeh| First 5 Authors: [#item_custom_name[1, [#item_custom_name[2, [#item_custom_name[3, [#item_custom_name[4, [#item_custom_name[5| Summary:The creation of lifelike human avatars capable of realistic pose variation and viewpoint flexibility remains a fundamental challenge in computer vision and graphics. Current approaches typically yield either geometrically inconsistent multi-view images or sacrifice photorealism, resulting in blurry outputs under diverse viewing […]


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Searches for Light Dark Matter and Evidence of Coherent Elastic Neutrino-Nucleus Scattering of Solar Neutrinos with the LUX-ZEPLIN (LZ) Experiment

Kavli Affiliate: N. C. Yeh| First 5 Authors: [#item_custom_name[1, [#item_custom_name[2, [#item_custom_name[3, [#item_custom_name[4, [#item_custom_name[5| Summary:We present searches for light dark matter (DM) with masses 3-9 GeV/$c^2$ in the presence of coherent elastic neutrino-nucleus scattering (CE$ν$NS) from $^8$B solar neutrinos with the LUX-ZEPLIN experiment. This analysis uses a 5.7 tonne-year exposure with data collected between March 2023 […]


Continue.. Searches for Light Dark Matter and Evidence of Coherent Elastic Neutrino-Nucleus Scattering of Solar Neutrinos with the LUX-ZEPLIN (LZ) Experiment

Searches for Light Dark Matter and Evidence of Coherent Elastic Neutrino-Nucleus Scattering of Solar Neutrinos with the LUX-ZEPLIN (LZ) Experiment

Kavli Affiliate: N. C. Yeh| First 5 Authors: [#item_custom_name[1, [#item_custom_name[2, [#item_custom_name[3, [#item_custom_name[4, [#item_custom_name[5| Summary:We present searches for light dark matter (DM) with masses 3-9 GeV/$c^2$ in the presence of coherent elastic neutrino-nucleus scattering (CE$ν$NS) from $^8$B solar neutrinos with the LUX-ZEPLIN experiment. This analysis uses a 5.7 tonne-year exposure with data collected between March 2023 […]


Continue.. Searches for Light Dark Matter and Evidence of Coherent Elastic Neutrino-Nucleus Scattering of Solar Neutrinos with the LUX-ZEPLIN (LZ) Experiment

Structure Theorems (and Fast Algorithms) for List Recovery of Subspace-Design Codes

Kavli Affiliate: G. Ravichandran| First 5 Authors: [#item_custom_name[1, [#item_custom_name[2, [#item_custom_name[3, [#item_custom_name[4, [#item_custom_name[5| Summary:List recovery of error-correcting codes has emerged as a fundamental notion with broad applications across coding theory and theoretical computer science. Folded Reed-Solomon (FRS) and univariate multiplicity codes are explicit constructions which can be efficiently list-recovered up to capacity, namely a fraction of […]


Continue.. Structure Theorems (and Fast Algorithms) for List Recovery of Subspace-Design Codes

SPHEREx Pre-Perihelion Mapping of $mathrmH_2O$, $mathrmCO_2$, and $mathrmCO$ in Interstellar Object 3I/ATLAS

Kavli Affiliate: James Bock| First 5 Authors: Carey M. Lisse, Carey M. Lisse, , , | Summary:From 01- to 15-Aug-2025 UT, the SPHEREx spacecraft observed interstellar object 3I/ATLAS. Using $R = 40$-$130$ spectrophotometry at $λ= 0.7$-$5μ$m, light curves, spectra, and imaging of 3I were obtained. From these, robust detections of water gas emission at $2.7$-$2.8,μ$m […]


Continue.. SPHEREx Pre-Perihelion Mapping of $mathrmH_2O$, $mathrmCO_2$, and $mathrmCO$ in Interstellar Object 3I/ATLAS

Exact 3-D Channel Impulse Response for Spherical Receivers with Arbitrary Drift Directions

Kavli Affiliate: N. C. Yeh| First 5 Authors: [#item_custom_name[1, [#item_custom_name[2, [#item_custom_name[3, [#item_custom_name[4, [#item_custom_name[5| Summary:Accurate channel modeling for spherical absorbing receivers is fundamental to the design of realistic molecular multiple-input multiple-output (MIMO) systems. While advanced modulation schemes have been proposed to mitigate interference, determining the channel impulse response (CIR) under arbitrary flow directions remains a challenge; […]


Continue.. Exact 3-D Channel Impulse Response for Spherical Receivers with Arbitrary Drift Directions

SQuARE: Structured Query & Adaptive Retrieval Engine For Tabular Formats

Kavli Affiliate: N. C. Yeh| First 5 Authors: [#item_custom_name[1, [#item_custom_name[2, [#item_custom_name[3, [#item_custom_name[4, [#item_custom_name[5| Summary:Accurate question answering over real spreadsheets remains difficult due to multirow headers, merged cells, and unit annotations that disrupt naive chunking, while rigid SQL views fail on files lacking consistent schemas. We present SQuARE, a hybrid retrieval framework with sheet-level, complexity-aware routing. […]


Continue.. SQuARE: Structured Query & Adaptive Retrieval Engine For Tabular Formats

Think Before You Prune: Self-Reflective Structured Pruning for Reasoning Language Models

Kavli Affiliate: N. C. Yeh| First 5 Authors: [#item_custom_name[1, [#item_custom_name[2, [#item_custom_name[3, [#item_custom_name[4, [#item_custom_name[5| Summary:Reasoning LLMs (RLMs) such as OpenAI o1, DeepSeek-R1, and Qwen3 deliver strong multi-step reasoning through chain-of-thought generation, but their large model sizes and lengthy decode-time outputs make them costly to deploy and unsuitable for resource-constrained settings. To reduce computing and memory cost, […]


Continue.. Think Before You Prune: Self-Reflective Structured Pruning for Reasoning Language Models

Young children’s anthropomorphism of an AI chatbot: Brain activation and the role of parent co-presence

Kavli Affiliate: N. C. Yeh| First 5 Authors: [#item_custom_name[1, [#item_custom_name[2, [#item_custom_name[3, [#item_custom_name[4, [#item_custom_name[5| Summary:Artificial Intelligence (AI) chatbots powered by a large language model (LLM) are entering young children’s learning and play, yet little is known about how young children construe these agents or how such construals relate to engagement. We examined anthropomorphism of a social […]


Continue.. Young children’s anthropomorphism of an AI chatbot: Brain activation and the role of parent co-presence