Inflammation-Responsive Micellar Nanoparticles from Degradable Polyphosphoramidates for Targeted Delivery to Myocardial Infarction

Kavli Affiliate: Karen Christman | Authors: Yifei Liang, Holly Sullivan, Kendal Carrow, Joanna Korpanty, Kendra Worthington, Colin Luo, Karen L Christman and Nathan C Gianneschi | Summary: ABSTRACT Nanoparticles that undergo a localized morphology change to target areas of inflammation have been previously developed but are limited by their lack of biodegradability. In this paper, […]


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Circuit dissection and functional validation of a cross-species emotional biomarker

Kavli Affiliate: Edward Chang, Vikaas Sohal | Authors: Adam Jackson, Josh Cohen, Aarron Phensy, Edward F Chang, Heather Dawes and Vikaas Sohal | Summary: ABSTRACT Emotional responses arise from limbic circuits including the hippocampus and amygdala. In the human brain, beta-frequency communication between these structures correlates with self-reported mood and anxiety. However, both the mechanism […]


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A Multi-Qubit Quantum Gate Using the Zeno Effect

Kavli Affiliate: Birgitta Whaley | First 5 Authors: Philippe Lewalle, Leigh S. Martin, Emmanuel Flurin, Song Zhang, Eliya Blumenthal | Summary: The Zeno effect, in which repeated observation freezes the dynamics of a quantum system, stands as an iconic oddity of quantum mechanics. When a measurement is unable to distinguish between states in a subspace, […]


Continue.. A Multi-Qubit Quantum Gate Using the Zeno Effect

A Multi-Qubit Quantum Gate Using the Zeno Effect

Kavli Affiliate: Birgitta Whaley | First 5 Authors: Philippe Lewalle, Leigh S. Martin, Emmanuel Flurin, Song Zhang, Eliya Blumenthal | Summary: The Zeno effect, in which repeated observation freezes the dynamics of a quantum system, stands as an iconic oddity of quantum mechanics. When a measurement is unable to distinguish between states in a subspace, […]


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Reduced cholecystokinin-expressing interneuron input contributes to disinhibition of the hippocampal CA2 region in a mouse model of temporal lobe epilepsy

Kavli Affiliate: Steven Siegelbaum | Authors: Alexander C Whitebirch, Anastasia Barnett, Bina Santoro, Helen E Scharfman and Steven A Siegelbaum | Summary: ABSTRACT A significant proportion of temporal lobe epilepsy (TLE) patients experience drug-resistant seizures associated with mesial temporal sclerosis, in which there is extensive cell loss in the hippocampal CA1 and CA3 subfields, with […]


Continue.. Reduced cholecystokinin-expressing interneuron input contributes to disinhibition of the hippocampal CA2 region in a mouse model of temporal lobe epilepsy

A comparative atlas of single-cell chromatin accessibility in the human brain

Kavli Affiliate: Michael Miller | Authors: Yang Eric Li, Sebastian Preissl, Michael Miller, Nicholas D. Johnson, Zihan Wang, Henry Jiao, Chenxu Zhu, Zhaoning Wang, Yang Xie, Olivier Poirin, Colin Kern, Antonio Pinto-Duarte, Wei Tian, Kimberly Siletti, Nora Emerson, Julia Osteen, Jacinta Lucero, Lin Lin, Qian Yang, Sarah Espinoza, Quan Zhu, Nathan Zemke, Anna Marie Yanny, […]


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Triplet Cooper pair splitting in a two-dimensional electron gas

Kavli Affiliate: Srijit Goswami | First 5 Authors: Qingzhen Wang, Sebastiaan L. D. ten Haaf, Ivan Kulesh, Di Xiao, Candice Thomas | Summary: Cooper pairs occupy the ground state of typical s-wave superconductors and are composed of maximally entangled electrons with opposite spin. In order to study the spin and entanglement properties of these electrons, […]


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Impact of half-wave plate systematics on the measurement of cosmic birefringence from CMB polarization

Kavli Affiliate: Eiichiro Komatsu | First 5 Authors: Marta Monelli, Eiichiro Komatsu, Alexandre E. Adler, Matteo Billi, Paolo Campeti | Summary: Polarization of the cosmic microwave background (CMB) can probe new parity-violating physics such as cosmic birefringence (CB), which requires exquisite control over instrumental systematics. The non-idealities of the half-wave plate (HWP) represent a source […]


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Potassium regulates axon-oligodendrocyte signaling and metabolic coupling in white matter

Kavli Affiliate: Dwight Bergles | Authors: Zoe J. Looser, Luca Ravotto, Ramona B. Jung, Hauke B. Werner, Torben Ruhwedel, Wiebke Moebius, Dwight E Bergles, L. Felipe Barros, Klaus-Armin Nave, Bruno Weber and Aiman S. Saab | Summary: Abstract The integrity of myelinated axons relies on homeostatic support from oligodendrocytes (OLs), which is essential for brain […]


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Flexible, Scalable, High Channel Count Stereo-Electrode for Recording in the Human Brain

Kavli Affiliate: Shadi Dayeh, Eric Halgren/p> | Authors: Keundong Lee, Angelique C Paulk, Yun Goo Ro, Daniel R Cleary, Karen J Tonsfeldt, Yoav Kfir, John Pezaris, Youngbin Tchoe, Jihwan Lee, Andrew M Bourhis, Ritwik Vatsyayan, Samantha M Russman, Jimmy C Yang, Amy Baohan, Mark Richardson, Ziv M Williams, Shelley Fried, Ahmed Raslan, Eric Halgren, Sydney […]


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