The Pandora project. I: the impact of radiation and cosmic rays on baryonic and dark matter properties of dwarf galaxies

Posted by klaurent Cambridge

Kavli Affiliate: Debora Sijacki | First 5 Authors: Sergio Martin-Alvarez, Debora Sijacki, Martin G. Haehnelt, Marion Farcy, Yohan Dubois | Summary: Enshrouded in several well-known controversies, dwarf galaxies have been extensively studied to learn about the underlying cosmology, notwithstanding that physical processes regulating their properties are poorly understood. To shed light on these processes, we […]


Continue.. The Pandora project. I: the impact of radiation and cosmic rays on baryonic and dark matter properties of dwarf galaxies

Tumor proliferation and invasion are coupled through cell-extracellular matrix friction

Posted by klaurent Hopkins

Kavli Affiliate: Denis Wirtz | Authors: Ashleigh J. Crawford, Clara Gomez-Cruz, Gabriella C. Russo, Wilson Huang, Isha Bhorkar, Arrate Munoz-Barrutia, Denis Wirtz and Daniel Garcia-Gonzalez | Summary: Abstract Cell proliferation and invasion are two key drivers of tumor progression and are traditionally considered two independent cellular processes regulated by distinct pathways. Through in vitro and […]


Continue.. Tumor proliferation and invasion are coupled through cell-extracellular matrix friction

A method of inferring partially observable Markov models from syllable sequences reveals the effects of deafening on Bengalese finch song syntax

Posted by klaurent UCSF

Kavli Affiliate: Kristofer Bouchard | Authors: Jiali Lu, Sumithra Surendralal, Kristofer E Bouchard and Dezhe Z. Jin | Summary: Abstract Songs of the Bengalese finch consist of variable sequences of syllables. The sequences follow probabilistic rules, and can be statistically described by partially observable Markov models (POMMs), which consist of states and probabilistic transitions between […]


Continue.. A method of inferring partially observable Markov models from syllable sequences reveals the effects of deafening on Bengalese finch song syntax

Robust and Fast Quantum State Transfer on Superconducting Circuits

Posted by klaurent Tokyo

Kavli Affiliate: Jia Liu | First 5 Authors: Xiao-Qing Liu, Jia Liu, Zheng-Yuan Xue, , | Summary: Quantum computation attaches importance to high-precision quantum manipulation, where the quantum state transfer with high fidelity is necessary. Here, we propose a new scheme to implement the quantum state transfer of high fidelity and long distance, by adding […]


Continue.. Robust and Fast Quantum State Transfer on Superconducting Circuits

Hierarchical Inference of the Lensing Convergence from Photometric Catalogs with Bayesian Graph Neural Networks

Posted by klaurent Stanford

Kavli Affiliate: Aaron Roodman | First 5 Authors: Ji Won Park, Simon Birrer, Madison Ueland, Miles Cranmer, Adriano Agnello | Summary: We present a Bayesian graph neural network (BGNN) that can estimate the weak lensing convergence ($kappa$) from photometric measurements of galaxies along a given line of sight. The method is of particular interest in […]


Continue.. Hierarchical Inference of the Lensing Convergence from Photometric Catalogs with Bayesian Graph Neural Networks

Hierarchical Inference of the Lensing Convergence from Photometric Catalogs with Bayesian Graph Neural Networks

Posted by klaurent Stanford

Kavli Affiliate: Philip J. Marshall | First 5 Authors: Ji Won Park, Simon Birrer, Madison Ueland, Miles Cranmer, Adriano Agnello | Summary: We present a Bayesian graph neural network (BGNN) that can estimate the weak lensing convergence ($kappa$) from photometric measurements of galaxies along a given line of sight. The method is of particular interest […]


Continue.. Hierarchical Inference of the Lensing Convergence from Photometric Catalogs with Bayesian Graph Neural Networks

Direct Cortical Inputs to Hippocampal Area CA1 Transmit Complementary Signals for Goal-directed Navigation

Posted by klaurent Columbia

Kavli Affiliate: Attila Losonczy | Authors: John C Bowler and Attila Losonczy | Summary: Summary The entorhinal cortex (EC) is central to the brain’s navigation system. Its subregions are conventionally thought to compute dichotomous representations for spatial processing: medial entorhinal cortex (MEC) provides a global spatial map, while lateral entorhinal cortex (LEC) encodes specific sensory […]


Continue.. Direct Cortical Inputs to Hippocampal Area CA1 Transmit Complementary Signals for Goal-directed Navigation

The HCN1 hyperpolarization-activated cyclic nucleotide-gated channel enhances evoked GABA release from parvalbumin positive interneurons

Posted by klaurent Columbia

Kavli Affiliate: Steven Siegelbaum | Authors: Tobias Bock, Eric W Buss, Olivia M Lofaro, Felix W Leroy, Bina Santoro and Steven A Siegelbaum | Summary: Abstract Hyperpolarization-activated, cyclic nucleotide-gated (HCN) channels generate the cationic Ih current in neurons and regulate the excitability of neuronal networks. The function of HCN channels depends, in part, on their […]


Continue.. The HCN1 hyperpolarization-activated cyclic nucleotide-gated channel enhances evoked GABA release from parvalbumin positive interneurons

Converting an allocentric goal into an egocentric steering signal

Posted by klaurent Rockefeller

Kavli Affiliate: Gaby Maimon | Authors: Peter Mussells Pires, L F Abbott and Gaby Maimon | Summary: Abstract Neuronal signals relevant for spatial navigation have been described in many species[1-12], however, a circuit-level understanding of how such signals interact to guide behaviour is lacking. Here we characterize a neuronal circuit in the Drosophila central complex […]


Continue.. Converting an allocentric goal into an egocentric steering signal

Tautomer-specific deacylation and Ω-loop flexibility explain carbapenem-hydrolyzing, broad-spectrum activity of the KPC-2 β-lactamase

Posted by klaurent Hopkins

Kavli Affiliate: Michael Beer | Authors: Catherine L Tooke, Philip Hinchliffe, Michael Beer, Kirill Zinovjev, Charlie K Colenso, Christopher J Schofield, Adrian J Mulholland and James Spencer | Summary: Abstract KPC-2 (Klebsiella pneumoniae carbapenemase-2) is a globally disseminated serine-β-lactamase (SBL) responsible for extensive β-lactam antibiotic resistance in Gram-negative pathogens. SBLs inactivate β-lactams via a mechanism […]


Continue.. Tautomer-specific deacylation and Ω-loop flexibility explain carbapenem-hydrolyzing, broad-spectrum activity of the KPC-2 β-lactamase