Two types of locus coeruleus norepinephrine neurons drive reinforcement learning

Kavli Affiliate: Jeremiah Cohen | Authors: Zhixiao Su and Jeremiah Y. Cohen | Summary: Abstract The cerebral cortex generates flexible behavior by learning. Reinforcement learning is thought to be driven by error signals in midbrain dopamine neurons. However, they project more densely to basal ganglia than cortex, leaving open the possibility of another source of […]


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Assessing the C/O Ratio Formation Diagnostic: A Potential Trend with Companion Mass

Kavli Affiliate: Bruce Macintosh | First 5 Authors: Kielan K. W. Hoch, Quinn M. Konopacky, Christopher A. Theissen, Jean-Baptiste Ruffio, Travis S. Barman | Summary: The carbon-to-oxygen (C/O) ratio in an exoplanet atmosphere has been suggested as a potential diagnostic of planet formation. Now that a number of exoplanets have measured C/O ratios, it is […]


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Visuomotor interactions in the mouse forebrain mediated by extrastriate cortico-cortical pathways

Kavli Affiliate: Menno Witter, Jonathan Whitlock | Authors: Karoline Hovde, Ida V. Rautio, Andrea Marie Hegstad, Menno P. Witter and Jonathan R. Whitlock | Summary: Abstract The mammalian visual system can be broadly divided into two functional processing pathways: a dorsal stream supporting visually and spatially guided actions, and a ventral stream enabling object recognition. […]


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Adult born hippocampal granule cells promote pattern separation by bidirectionally modulating the remapping of place and cue cells

Kavli Affiliate: Rene Hen | Authors: Sebnem N. Tuncdemir, Andres D. Grosmark, Hannah Chung, Victor M. Luna, Clay O. Lacefield, Attila Losonczy and Rene Hen | Summary: Abstract The hippocampal dentate gyrus (DG) exhibits a unique form of neural plasticity that results from continuous integration of adult born neurons, referred to as ‘adult neurogenesis’. Recent […]


Continue.. Adult born hippocampal granule cells promote pattern separation by bidirectionally modulating the remapping of place and cue cells

Directional detection of dark matter with anisotropic response functions

Kavli Affiliate: Noah Kurinsky | First 5 Authors: Christian Boyd, Yonit Hochberg, Yonatan Kahn, Eric David Kramer, Noah Kurinsky | Summary: Direct detection for sub-GeV dark matter is developing rapidly, with many novel experimental ideas and theoretical methods emerging. In this work, we extend the dielectric formalism for dark matter scattering to incorporate anisotropic material […]


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Directional detection of dark matter with anisotropic response functions

Kavli Affiliate: Noah Kurinsky | First 5 Authors: Christian Boyd, Yonit Hochberg, Yonatan Kahn, Eric David Kramer, Noah Kurinsky | Summary: Direct detection for sub-GeV dark matter is developing rapidly, with many novel experimental ideas and theoretical methods emerging. In this work, we extend the dielectric formalism for dark matter scattering to incorporate anisotropic material […]


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Dual electro-optic frequency comb photonic thermometry

Kavli Affiliate: Zeeshan Ahmed | First 5 Authors: Adam J. Fleisher, Zeeshan Ahmed, Tobias Herman, Matthew R. Hartings, | Summary: We report a precision realization of photonic thermometry using dual-comb spectroscopy to interrogate a $pi$-phase-shifted fiber Bragg grating. We achieve read-out stability of 7.5 mK at 1 s and resolve temperature changes of similar magnitude–sufficient […]


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Nostradamus: Weathering Worth

Kavli Affiliate: Zeeshan Ahmed | First 5 Authors: Alapan Chaudhuri, Zeeshan Ahmed, Ashwin Rao, Shivansh Subramanian, Shreyas Pradhan | Summary: Nostradamus, inspired by the French astrologer and reputed seer, is a detailed study exploring relations between environmental factors and changes in the stock market. In this paper, we analyze associative correlation and causation between environmental […]


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Engineered retrovirus-like Arc extracellular vesicles for the in vivo targeted delivery of mRNA into the brain

Kavli Affiliate: Robert Hawkins | Authors: Wenchao Gu, Sijin Luozhong, Ketaki Londhe, Nadine Elkasri, Simian Cai, Robert Hawkins, Zhefan Yuan, Kai Su-Greene, Margaret Cruz, Yu-Wei Chang, Patrick McMullen, Chunyan Wu, Changwoo Seo, Akash Guru, Wenting Gao, Tara Sarmiento, Chris Schaffer, Nozomi Nishimura, Richard Cerione, Melissa Warden, Robert Langer and Shaoyi Jiang | Summary: Abstract Systemic […]


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Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins (RAMPs)

Kavli Affiliate: Thomas P. Sakmar | Authors: Ilana B. Kotliar, Emilie Ceraudo, Kevin Kemelmakher-Liben, Deena A. Oren, Emily Lorenzen, Tea Dodig-Crnković, Mizuho Horioka-Duplix, Thomas Huber, Jochen M. Schwenk and Thomas P. Sakmar | Summary: Abstract Cholestatic itch is a severe and debilitating symptom in liver diseases with limited treatment options. The class A G protein-coupled […]


Continue.. Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins (RAMPs)