Kavli Affiliate: Jia Liu | First 5 Authors: Fan Jiang, Mingchen Li, Jiajun Dong, Yuanxi Yu, Xinyu Sun | Summary: Designing protein mutants of both high stability and activity is a critical yet challenging task in protein engineering. Here, we introduce PRIME, a deep learning model, which can suggest protein mutants of improved stability and […]
Kavli Affiliate: Scott A. Hughes | First 5 Authors: Lorenzo Speri, Michael L. Katz, Alvin J. K. Chua, Scott A. Hughes, Niels Warburton | Summary: Extreme Mass Ratio Inspirals (EMRIs) are one of the key sources for future space-based gravitational wave interferometers. Measurements of EMRI gravitational waves are expected to determine the characteristics of their […]
Kavli Affiliate: Scott A. Hughes | First 5 Authors: Lorenzo Speri, Michael L. Katz, Alvin J. K. Chua, Scott A. Hughes, Niels Warburton | Summary: Extreme Mass Ratio Inspirals (EMRIs) are one of the key sources for future space-based gravitational wave interferometers. Measurements of EMRI gravitational waves are expected to determine the characteristics of their […]
Kavli Affiliate: Katia Bertoldi | First 5 Authors: Xiaoxiao Ding, Vanessa Sanchez, Katia Bertoldi, Chris H. Rycroft, | Summary: Knitting interloops one-dimensional yarns into three-dimensional fabrics that exhibit behaviours beyond their constitutive materials. How extensibility and anisotropy emerge from the hierarchical organisation of yarns into knitted fabrics has long been unresolved. We sought to unravel […]
Kavli Affiliate: Joel E. Moore | First 5 Authors: Yu-Ping Lin, Chunxiao Liu, Joel E. Moore, , | Summary: We present the mean-field phase diagram of electrons in a kagome flat band with repulsive interactions. In addition to flat-band ferromagnetism, the Hartree-Fock analysis yields cascades of unconventional magnetic orders driven by onsite repulsion as filling […]
Kavli Affiliate: Ariel Amir | First 5 Authors: Wencheng Ji, Ori Hachmo, Naama Barkai, Ariel Amir, | Summary: Transcription Factors (TFs) are proteins crucial for regulating gene expression. Effective regulation requires the TFs to rapidly bind to the correct target, enabling the cell to respond timely to various stimuli such as nutrient availability or toxin […]
Kavli Affiliate: Ariel Amir | First 5 Authors: Wencheng Ji, Ori Hachmo, Naama Barkai, Ariel Amir, | Summary: Transcription Factors (TFs) are proteins that regulate gene expression. The regulation mechanism is via the binding of a TF to a specific part of the gene associated with it, the TF’s target. For the regulation to be […]
Kavli Affiliate: Erin Kara | First 5 Authors: Collin Lewin, Erin Kara, Edward M. Cackett, Dan Wilkins, Christos Panagiotou | Summary: UV and optical continuum reverberation mapping is powerful for probing the accretion disk and inner broad-line region. However, recent reverberation mapping campaigns in the X-ray, UV, and optical have found lags consistently longer than […]
Kavli Affiliate: Maria Elena Monzani | First 5 Authors: David A. Smith, Philippe Bruel, Colin J. Clark, Lucas Guillemot, Matthew T. Kerr | Summary: We present 294 pulsars found in GeV data from the Large Area Telescope (LAT) on the Fermi Gamma-ray Space Telescope. Another 33 millisecond pulsars (MSPs) discovered in deep radio searches of […]
Kavli Affiliate: Maria Elena Monzani | First 5 Authors: David A. Smith, Philippe Bruel, Colin J. Clark, Lucas Guillemot, Matthew T. Kerr | Summary: We present 294 pulsars found in GeV data from the Large Area Telescope (LAT) on the Fermi Gamma-ray Space Telescope. Another 33 millisecond pulsars (MSPs) discovered in deep radio searches of […]