Homozygosity for rare or common hypomorphic IL23R variants confers a predisposition to tuberculosis in humans

Posted by klaurent Rockefeller

Kavli Affiliate: Jean-Laurent Casanova | Authors: Diana Olguin Calderon, Laura E. Kilpatrick, Clement Conil, Quentin Philippot, Masato Ogishi, Joseph Vellutini, Ji Eun Han, Narelle Keating, Hailun Li, Geetha Rao, Jonathan Bohlen, Charles S. Lay, Simon Platt, Gaspard Kerner, Elsa Feredj, Jessica Peel, Mana Momenilandi, Yoann Seeleuthner, Candice Laine, camille soudee, Claire Leloup, Cecile Debuisson, Fanny […]


Continue.. Homozygosity for rare or common hypomorphic IL23R variants confers a predisposition to tuberculosis in humans

GPCRs as Targets for Human Brain Modulation: A Multi-omic Atlas of Cell-Type Specific Expression

Posted by klaurent Rockefeller

Kavli Affiliate: Nathaniel Heintz | Authors: Alan Umfress, Patrick Wertimer, Christina Pressl, Matthew Baffuto, Kert Mätlik, Franchesca Fernandez, Maria Esterlita Siantoputri, Ines Ibañez-Tallon and Nathaniel Heintz | Summary: G Protein coupled receptors (GPCRs) are the largest class of clinically validated drug targets with nearly 35% of all approved therapeutic agents acting on these receptors. To […]


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The Vera C. Rubin Observatory Data Preview 1

Posted by klaurent Stanford

Kavli Affiliate: Steven Kahn | Summary:We present Rubin Data Preview 1 DP1, the first data from the NSF DOE Vera C Rubin Observatory, comprising raw and calibrated single epoch images, coadds, difference images, detection catalogs, and ancillary data products. DP1 is based on 1792 optical near infrared exposures acquired over 48 distinct nights by the […]


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Reconciling strange metal transport in CeCoIn$_5$ through the difference of optical and cyclotron effective masses

Posted by klaurent Cornell

Kavli Affiliate: Darrell Schlom | Summary:The strange metal behavior in cuprate superconductors – characterized by linear in temperature resistivity and anomalous Hall transport – stands in stark contrast to the expectation of conventional Fermi liquid (FL) theory. Remarkably, the similar transport behavior has also been observed in the heavy fermion metal CeCoIn$_5$, whose d-wave superconducting […]


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Brightest Cluster Galaxy ellipticity as proxy for halo shape: Orientation bias, assembly bias, and potential selection effects in SZ-selected clusters

Posted by klaurent MIT

Kavli Affiliate: Michael McDonald | Summary:The orientation of triaxial galaxy clusters with respect to the line-of-sight is expected to be one of the prime sources of scatter and potential bias in optical observables (e.g., richness and weak-lensing signal) of galaxy clusters. In this work, we use the observed shape of the central Brightest Cluster Galaxy […]


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FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets

Posted by dbos UCSD / Salk

Kavli Affiliate: Anders Dale and Wesley Thompson | Authors: Pravesh Parekh, Nadine Parker, Diliana Pecheva, Evgeniia Frei, Marc Vaudel, Diana M. Smith, Alison Rigby, Piotr Jahołkowski, Ida Elken Sønderby, Viktoria Birkenæs, Nora Refsum Bakken, Chun Chieh Fan, Carolina Makowski, Jakub Kopal, Robert John Loughnan, Donald J. Hagler, Jr., Dennis van der Meer, Stefan Johansson, Pål […]


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SPHEREx mapping of diffuse PAH and H II emission in the Galactic plane

Posted by klaurent Caltech

Kavli Affiliate: James Bock | Summary:We present preliminary SPHEREx maps of diffuse Galactic emission tracing polycyclic aromatic hydrocarbons (PAHs) and ionized hydrogen gas, and we study their relationship across the Galactic plane. Since its launch in early 2025, the SPHEREx space telescope has been conducting an all-sky near-infrared spectral survey from 0.75 to 5.0 microns. […]


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SPHEREx mapping of diffuse PAH and H II emission in the Galactic plane

Posted by klaurent Caltech

Kavli Affiliate: James Bock | Summary:We present preliminary SPHEREx maps of diffuse Galactic emission tracing polycyclic aromatic hydrocarbons (PAHs) and ionized hydrogen gas, and we study their relationship across the Galactic plane. Since its launch in early 2025, the SPHEREx space telescope has been conducting an all-sky near-infrared spectral survey from 0.75 to 5.0 microns. […]


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Quantum Saturation of the Electro-Optic Effect

Posted by klaurent Cornell

Kavli Affiliate: Darrell Schlom | Summary:Future quantum computing architectures require electro-optic materials that maintain a strong, stable performance at cryogenic temperatures. In conventional electro-optic materials, large electro-optic coefficients are often confined to narrow temperature windows near structural phase transitions, where small changes in temperature lead to large changes in the electro-optic response. Using thermodynamic analysis, […]


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Causal Reconstruction of Sentiment Signals from Sparse News Data

Posted by klaurent Peking

Kavli Affiliate: Claudio Ricci | Summary:Sentiment signals derived from sparse news are commonly used in financial analysis and technology monitoring, yet transforming raw article-level observations into reliable temporal series remains a largely unsolved engineering problem. Rather than treating this as a classification challenge, we propose to frame it as a causal signal reconstruction problem: given […]


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