Robust PHP in Adult Hippocampus: Essential Assay Optimizations

Kavli Affiliate: Graeme Davis | Authors: Peter H. Chipman, Richard D. Fetter, Forrest J. Ragozzino, Unghwi Lee and Graeme W. Davis | Summary: Presynaptic homeostatic plasticity (PHP) is a potent form of homeostatic plasticity that has been documented at synapses as diverse as the glutamatergic Drosophila neuromuscular junction (NMJ), cholinergic mammalian NMJ (including human), and […]


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The effects of ionic valency and size asymmetry on counterion adsorption

Kavli Affiliate: Rudolf Podgornik | Summary:We study the effect of asymmetry in solvent and ionic size on the equilibrium properties of multivalent ionic solutions near a charged surface. For a single ionic species in solution, we derive a generalized Grahame equation at the charged surface. For general size ratio between the ions and the solvent, […]


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Non-canonical DNA in bird telomere-to-telomere genomes

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Erich Jarvis | Authors: Linnea Smeds, Jacob P Sieg, Simona Secomandi, Chul Lee, Marco Sollitto, Jack A Medico, Francesca Chiaromonte, Erich D Jarvis, Giulio Formenti and Kateryna D Makova | Summary: Non-canonical (non-B) DNA motifs are sequences that can fold […]


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Deconstructed Weak Isospin from a Symplectic Symmetry

Kavli Affiliate: David W. Miller | Summary:Understanding the origin of flavour hierarchies in the Standard Model remains an open problem, motivating extensions with non-trivial flavour symmetries. We unify deconstructed weak isospin $mathrmSU(2)_mathrmL^3$ into an $mathrmSp(6)_mathrmL$ symmetry at a high scale $v_S$. The three generations of Standard Model (SM) left-handed doublets are unified into a single […]


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$mathrmSp(6)$ Unifying Deconstructed $mathrmSU(2)$’s

Kavli Affiliate: David W. Miller | Summary:Understanding the origin of flavour hierarchies in the Standard Model remains an open problem, motivating extensions with non-trivial flavour symmetries. We unify deconstructed weak isospin $mathrmSU(2)_mathrmL^3$ into an $mathrmSp(6)_mathrmL$ symmetry at a high scale $v_S$. The three generations of Standard Model (SM) left-handed doublets are unified into a single […]


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The cold molecular gas regulates the activity of active galactic nuclei in massive galaxies

Kavli Affiliate: Luis Ho | Summary:The physical quantities that directly regulate AGN feedback in massive galaxies remain poorly understood. Observations of molecular gas surrounding AGNs suggest that this gas serves as a fuel source for AGN activity. Accordingly, we study the relationship between AGN activity and molecular gas properties. In this study, we analyze a […]


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Neurodegeneration risk variants promote lysosomal TMEM106B fibril accumulation

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Shawn Ferguson | Authors: John Michael Replogle, Jordan D Marks, Martin G Fernandez, Hebao Yuan, Belle Yu, Elizabeth Winters, Vidhya Maheswari Jawahar, Rishi Deshmukh, Renaldo Sutanto, Isabelle Kowal, Ashley Frankenfield, Rachel Shi, Yari Carlomagno, Karen Jansen-West, Tiffany Todd, Andrii Kopach, […]


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Transformations of cognitive maps for sensorimotor control

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Vikram Chib | Authors: Joonhee Leo Lee, Yixuan Wang, Agostina Casamento-Moran, Kosisochukwu Ugorji, Jose Jarquin, Daniel C McNamee and Vikram S Chib | Summary: Adaptive embodied behavior involves transforming structured knowledge about the relationship between environment and action into motor […]


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A cosmological framework for stellar collisions at high redshift in proto-globular clusters, nuclear star clusters, and Little Red Dots

Kavli Affiliate: Mark Vogelsberger | Summary:Observations and cosmological simulations indicate that the early Universe hosted numerous compact, high-density stellar systems, where close encounters and physical collisions between stars were likely common. We develop a bottom-up framework for stellar dynamics in such environments, spanning systems with and without intermediate- and supermassive black holes, and covering regimes […]


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ASAS-SN Rates IV: Constraints on the Kilonova Rate

Kavli Affiliate: Subo Dong | Summary:Kilonovae (KNe) are the electromagnetic signatures of neutron star mergers and are likely the dominant site of cosmic $r$-process nucleosynthesis. However, their intrinsic rate remains poorly constrained due to a paucity of confirmed events. We use the All-Sky Automated Survey for Supernovae (ASAS-SN) to place limits on the rate of […]


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