Social Exclusion Amplifies Behavioral Responses to Physical Pain via Insular Neuromodulation

Kavli Affiliate: Kay Tye | Authors: Caroline Jia, Andrea Tran, Faith Aloboudi, Ella Say, Nick Thao, Christopher R. Lee, Kanha Batra, Amanda Nguyen, Aneesh Bal, Nathaniel N. Nono, Jeremy Delahanty, May G Chan, Laurel R. Keyes, Reesha R. Patel, Romy Wichmann, Felix Taschbach, Yulong Li, Marcus K. Benna, Talmo D Pereira, Hao Li and Kay […]


Continue.. Social Exclusion Amplifies Behavioral Responses to Physical Pain via Insular Neuromodulation

A framework for analyzing C. elegans neural activity using multi-dimensional hyperbolic embedding

Kavli Affiliate: Tatyana Sharpee and Sreekanth Chalasani | Authors: Iulia Rusu, Zachary T Cecere, Javier J How, Kathleen T Quach, Eviatar Yemini, Tatyana O Sharpee and Sreekanth H Chalasani | Summary: Neurons represent changes in external and internal environments by altering their activity patterns. While coherent brain-wide patterns of neural activity have been observed in […]


Continue.. A framework for analyzing C. elegans neural activity using multi-dimensional hyperbolic embedding

A protective role of REM sleep in the pathological basal ganglia-cortical circuit of Parkinson’s disease

Kavli Affiliate: Philip Starr | Authors: Jin-Xiao Zhang, Clay Smyth, Md Fahim Anjum, Yue Leng, Andrew D. Krystal, Philip A. Starr and Simon Little | Summary: Sleep disturbance is involved in the progression of neurodegenerative diseases, but the neurophysiological mechanisms remain unclear in humans. We recorded sleep at home using portable polysomnography for multiple nights […]


Continue.. A protective role of REM sleep in the pathological basal ganglia-cortical circuit of Parkinson’s disease

Working memory by distributed neural oscillators in a simple nervous system

Kavli Affiliate: Noelle L’Etoile and Saul Kato | Authors: Raymond L Dunn, Caitriona Costello, Jackson M Borchardt, Daniel Yutaka Sprague, Grace C Chiu, Julia M Miller, Noelle L’Etoile and Saul Kato | Summary: Working memory allows an animal to gather sensory evidence over time, integrate it with evolving internal needs, and make informed decisions about […]


Continue.. Working memory by distributed neural oscillators in a simple nervous system

Defect in hematopoiesis and embryonic lethality at midgestation of Vps13a/Vps13c double knockout mice

Kavli Affiliate: Pietro De Camilli | Authors: Peng Xu, Rubia Isler Mancuso, Marianna Leonzino, Caroline J Zeiss, Diane S Krause and Pietro De Camilli | Summary: VPS13 is the founding member of a family of proteins that mediate lipid transfer at intracellular membrane contact sites by a bridge-like mechanism. Mammalian genomes comprise 4 VPS13 genes […]


Continue.. Defect in hematopoiesis and embryonic lethality at midgestation of Vps13a/Vps13c double knockout mice

A High-Quality Composite Pati-Salam Axion

Kavli Affiliate: Hitoshi Murayama | First 5 Authors: Tony Gherghetta, Hitoshi Murayama, Pablo Quílez, , | Summary: We present a composite QCD axion model where the Peccei–Quinn (PQ) symmetry emerges as a high-quality, accidental symmetry. The axion potential is only modified by eight-fermion, dimension 12 operators, which if present at the Planck scale, allow for […]


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DynamicDTA: Drug-Target Binding Affinity Prediction Using Dynamic Descriptors and Graph Representation

Kavli Affiliate: Dan Luo | First 5 Authors: Dan Luo, Jinyu Zhou, Le Xu, Sisi Yuan, Xuan Lin | Summary: Predicting drug-target binding affinity (DTA) is essential for identifying potential therapeutic candidates in drug discovery. However, most existing models rely heavily on static protein structures, often overlooking the dynamic nature of proteins, which is crucial […]


Continue.. DynamicDTA: Drug-Target Binding Affinity Prediction Using Dynamic Descriptors and Graph Representation

Search for lepton flavor-violating decay modes $B^0 to K^{ast 0}τ^pmell^mp$ ($ell = e,μ$) with hadronic B-tagging at Belle and Belle II

Kavli Affiliate: T. Higuchi | First 5 Authors: Belle, Belle II Collaborations, :, I. Adachi, Y. Ahn | Summary: We present the results of a search for the charged-lepton-flavor violating decays $B^0 rightarrow K^{*0}tau^pm ell^{mp}$, where $ell^{mp}$ is either an electron or a muon. The results are based on 365 fb$^{-1}$ and 711 fb$^{-1}$ datasets […]


Continue.. Search for lepton flavor-violating decay modes $B^0 to K^{ast 0}τ^pmell^mp$ ($ell = e,μ$) with hadronic B-tagging at Belle and Belle II