Cell-type-selective synaptogenesis during the development of excitatory connectivity in the mammalian neocortex

Kavli Affiliate: Alex Kolodkin and Solange Brown | Authors: Alan Y. Gutman-Wei, Sriram Sudarsanam, Alec G. Cabalinan, Naseer Shahid, Anny Shi, Luis E. Guzman Clavel, Sophia M. Spindler-Krage, Amit Agarwal, Alex L. Kolodkin and Solange P. Brown | Summary: The function of mammalian neocortex relies on the timing of axon extension and establishment of cell-type-biased […]


Continue.. Cell-type-selective synaptogenesis during the development of excitatory connectivity in the mammalian neocortex

Learning More by Seeing Less: Structure First Learning for Efficient, Transferable, and Human-Aligned Vision

Kavli Affiliate: Yuchong Tai | First 5 Authors: Tianqin Li, Tianqin Li, , , | Summary: Despite remarkable progress in computer vision, modern recognition systems remain fundamentally limited by their dependence on rich, redundant visual inputs. In contrast, humans can effortlessly understand sparse, minimal representations like line drawings, suggesting that structure, rather than appearance, underlies […]


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Second public data release of the FIRE-2 cosmological zoom-in simulations of galaxy formation

Kavli Affiliate: Lina Necib | Summary:We describe the second data release (DR2) of the FIRE-2 cosmological zoom-in simulations of galaxy formation, from the Feedback In Realistic Environments (FIRE) project, available at http://flathub.flatironinstitute.org/fire. DR2 includes all snapshots for most simulations, starting at z ~ 99, with all snapshot time spacings <~ 25 Myr. The Core suite […]


Continue.. Second public data release of the FIRE-2 cosmological zoom-in simulations of galaxy formation

GLM-4.5: Agentic, Reasoning, and Coding (ARC) Foundation Models

Kavli Affiliate: Ke Wang | First 5 Authors: GLM-4. 5 Team, GLM-4. 5 Team, , , | Summary: We present GLM-4.5, an open-source Mixture-of-Experts (MoE) large language model with 355B total parameters and 32B activated parameters, featuring a hybrid reasoning method that supports both thinking and direct response modes. Through multi-stage training on 23T tokens […]


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Gate reflectometry in a minimal Kitaev chain device

Kavli Affiliate: Srijit Goswami | Summary:Hybrid quantum dot (QD)-superconductor system can be used to realize Majorana zero modes in artificial Kitaev chains. These chains provide a promising platform for the realization of Majorana qubits. Radio-frequency (RF) gate reflectometry is a fast, non-invasive, and sensitive technique that can be used to read out such qubits. In […]


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Bayesian online collective anomaly and change point detection in fine-grained time series

Kavli Affiliate: Xian Chen | First 5 Authors: Xian Chen, Xian Chen, , , | Summary: Fine-grained time series data are crucial for accurate and timely online change detection. While both collective anomalies and change points can coexist in such data, their joint online detection has received limited attention. In this research, we develop a […]


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DAFMSVC: One-Shot Singing Voice Conversion with Dual Attention Mechanism and Flow Matching

Kavli Affiliate: Dan Luo | First 5 Authors: Wei Chen, Wei Chen, , , | Summary: Singing Voice Conversion (SVC) transfers a source singer’s timbre to a target while keeping melody and lyrics. The key challenge in any-to-any SVC is adapting unseen speaker timbres to source audio without quality degradation. Existing methods either face timbre […]


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StCEL-based platform enables detection and sequencing of native sialoglycoRNA

Kavli Affiliate: Wei Min | Authors: Guang-Dong Zeng, Yun-Long Wang, Xu-Hui Chen, Yi Ma, Zhu Zhu, Huan-Lei Liu, Li-Yuan Fan, Hao Nan, Ziwaregul Nur, Min Wei, Xin-Yuan Liu, Li Yi, Jiu-Yu Jin, Yu-Song Cao, Meng-Bo Qiu, Wei-Peng Sun, Yang Bai, Quan-Bo Zhou, Guo-Qing Zhang, Jing-Feng Chen, Jie Shi, Jian Zheng, Yixuan Xie, Peng Li, Xiang-Bo […]


Continue.. StCEL-based platform enables detection and sequencing of native sialoglycoRNA