Multiple interactions mediate the localization of BLTP2 at ER-PM contacts to control plasma membrane dynamics

Kavli Affiliate: Pietro De Camilli | Authors: Anbang Dai, Peng Xu, Chase Amos, Kenshiro Fujise, Yumei Wu, Han Yang, Julia N. Eisen, Andrés Guillén-Samander and Pietro De Camilli | Summary: BLTP2/KIAA0100, a bridge-like lipid transfer protein, was reported to localize at contacts of the endoplasmic reticulum (ER) with either the plasma membrane (PM) or recycling […]


Continue.. Multiple interactions mediate the localization of BLTP2 at ER-PM contacts to control plasma membrane dynamics

Optogenetic restoration of neuron subtype-specific cortical activity ameliorates motor deficits in Huntington′s Disease mice

Kavli Affiliate: Takaki Komiyama | Authors: Sonja Blumenstock, David Arakelyan, Nicholas del Grosso, Sonja Schneider, Yufeng Shao, Enida Gjoni, Ruediger Klein, Irina Dudanova and Takaki Komiyama | Summary: Huntington′s disease (HD) is a devastating movement disorder without a current cure. Although the monogenic basis of HD is well-defined, the complex downstream effects that underlie behavioral […]


Continue.. Optogenetic restoration of neuron subtype-specific cortical activity ameliorates motor deficits in Huntington′s Disease mice

Old vs. New Local Ancestry Inference in HCHS/SOL: A Comparative Study

Kavli Affiliate: Anders Dale | Authors: Xueying Chen, Hao Wang, Iris Broce, Anders M Dale, Bing Yu, Laura Y Zhou, Xihao Li, Maria Argos, Martha L Daviglus, Jianwen Cai, Nora Franceschini and Tamar Sofer | Summary: Hispanic/Latino populations are admixed, with genetic contributions from multiple ancestral populations. Studies of genetic association in these admixed populations […]


Continue.. Old vs. New Local Ancestry Inference in HCHS/SOL: A Comparative Study

Context-specific interaction of the lipid regulator DIP-2 with phospholipid synthesis in axon regeneration and maintenance.

Kavli Affiliate: Yishi Jin | Authors: Seungmee Park, Andrew D. Chisholm and Yishi Jin | Summary: Neurons maintain their morphology over prolonged periods of adult life with limited regeneration after injury. C. elegans DIP-2 is a conserved regulator of lipid metabolism that affects axon maintenance and regeneration after injury. Here, we investigated genetic interactions of […]


Continue.. Context-specific interaction of the lipid regulator DIP-2 with phospholipid synthesis in axon regeneration and maintenance.

Evaluation of sequencing reads at scale using rdeval

Kavli Affiliate: Erich Jarvis | Authors: Giulio Formenti, Bonhwang Koo, Marco Sollitto, Jennifer Balacco, Nadolina Brajuka, Richard Burhans, Erick Duarte, Alice Maria Giani, Kirsty McCaffrey, Jack A Medico, Eugene W Myers, Patrik Smeds, Anton Nekrutenko and Erich D Jarvis | Summary: Motivation: Large sequencing data sets are produced and deposited into public archives at unprecedented […]


Continue.. Evaluation of sequencing reads at scale using rdeval

Optogenetic interrogation of the lateral-line sensory system reveals mechanisms of pattern separation in the zebrafish brain

Kavli Affiliate: A. James Hudspeth | Authors: Nicolas Velez, Sihao Lu, Brian Fabella, Caleb C. Reagor, Holland R Brown, Yuriria Vazquez, Adrian Jacobo and Albert James Hudspeth | Summary: The ability of animals to interact with their environment hinges on the brain’s capacity to distinguish between patterns of sensory information and accurately attribute them to […]


Continue.. Optogenetic interrogation of the lateral-line sensory system reveals mechanisms of pattern separation in the zebrafish brain

A Response to Recent Critiques of Hainmueller, Mummolo and Xu (2019) on Estimating Conditional Relationships

Kavli Affiliate: Chris Xu | First 5 Authors: Jens Hainmueller, Jens Hainmueller, , , | Summary: Simonsohn (2024a) and Simonsohn (2024b) critique Hainmueller, Mummolo and Xu (2019, HMX), arguing that failing to model nonlinear relationships between the treatment and moderator leads to biased marginal effect estimates and uncontrolled Type-I error rates. While these critiques highlight […]


Continue.. A Response to Recent Critiques of Hainmueller, Mummolo and Xu (2019) on Estimating Conditional Relationships

Generalizable Radio-Frequency Radiance Fields for Spatial Spectrum Synthesis

Kavli Affiliate: Hsiaowen Chen| First 5 Authors: [#item_custom_name[1, [#item_custom_name[2, [#item_custom_name[3, [#item_custom_name[4, [#item_custom_name[5| Summary:We present GRaF, Generalizable Radio-Frequency (RF) Radiance Fields, a framework that models RF signal propagation to synthesize spatial spectra at arbitrary transmitter or receiver locations, where each spectrum measures signal power across all surrounding directions at the receiver. Unlike state-of-the-art methods that adapt […]


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Superconducting Properties of the Titanium-Based Oxides Compounds: A Review

Kavli Affiliate: Yi Zhou | First 5 Authors: Junqi He, Yi Zhou, , , | Summary: In recent years, the superconductivity of novel layered materials, titanium-based pnictide oxides, was discovered. Due to the properties of possessing both cuprate and iron-based superconductors, these compounds have attracted the interest of researchers. Titanium pnictide oxides were reported to […]


Continue.. Superconducting Properties of the Titanium-Based Oxides Compounds: A Review