On the mechanism of polaritonic rate suppression from quantum transition paths

Kavli Affiliate: David T. Limmer | First 5 Authors: Michelle C. Anderson, Esmae J. Woods, Thomas P. Fay, David J. Wales, David T. Limmer | Summary: Polariton chemistry holds promise for facilitating mode-selective chemical reactions, but the underlying mechanism behind the rate modifications observed under vibrational strong coupling is not well understood. Using the recently […]


Continue.. On the mechanism of polaritonic rate suppression from quantum transition paths

The effect of scatter of polymer chain length on strength

Kavli Affiliate: Zhigang Suo | First 5 Authors: Manyuan Tao, Shawn Lavoie, Zhigang Suo, Maria K. Cameron, | Summary: A polymer network fractures by breaking covalent bonds, but the experimentally measured strength of the polymer network is orders of magnitude lower than the strength of covalent bonds. We investigate the effect of statistical variation of […]


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X-ray Polarization of the Black Hole X-ray Binary 4U 1630-47 Challenges Standard Thin Accretion Disk Scenario

Kavli Affiliate: Herman Marshall | First 5 Authors: Ajay Ratheesh, Michal Dovčiak, Henric Krawczynski, Jakub Podgorný, Lorenzo Marra | Summary: Large energy-dependent X-ray polarization degree is detected by the Imaging X-ray Polarimetry Explorer ({IXPE}) in the high-soft emission state of the black hole X-ray binary 4U 1630–47. The highly significant detection (at $approx50sigma$ confidence level) […]


Continue.. X-ray Polarization of the Black Hole X-ray Binary 4U 1630-47 Challenges Standard Thin Accretion Disk Scenario

X-ray Polarization of the Black Hole X-ray Binary 4U 1630-47 Challenges Standard Thin Accretion Disk Scenario

Kavli Affiliate: Herman Marshall | First 5 Authors: Ajay Ratheesh, Michal Dovčiak, Henric Krawczynski, Jakub Podgorný, Lorenzo Marra | Summary: Large energy-dependent X-ray polarization degree is detected by the Imaging X-ray Polarimetry Explorer ({IXPE}) in the high-soft emission state of the black hole X-ray binary 4U 1630–47. The highly significant detection (at $approx50sigma$ confidence level) […]


Continue.. X-ray Polarization of the Black Hole X-ray Binary 4U 1630-47 Challenges Standard Thin Accretion Disk Scenario

The high polarisation of the X-rays from the Black Hole X-ray Binary 4U 1630-47 challenges standard thin accretion disc scenario

Kavli Affiliate: Herman Marshall | First 5 Authors: Ajay Ratheesh, Michal Dovčiak, Henric Krawczynski, Jakub Podgorný, Lorenzo Marra | Summary: Large, energy-dependent X-ray polarisation is observed in 4U 1630-47, a black hole in an X-ray binary, in the high-soft emission state. In this state, X-ray emission is believed to be dominated by a thermal, geometrically […]


Continue.. The high polarisation of the X-rays from the Black Hole X-ray Binary 4U 1630-47 challenges standard thin accretion disc scenario

The high polarisation of the X-rays from the Black Hole X-ray Binary 4U 1630-47 challenges standard thin accretion disc scenario

Kavli Affiliate: Roger Romani | First 5 Authors: Ajay Ratheesh, Michal Dovčiak, Henric Krawczynski, Jakub Podgorný, Lorenzo Marra | Summary: Large, energy-dependent X-ray polarisation is observed in 4U 1630-47, a black hole in an X-ray binary, in the high-soft emission state. In this state, X-ray emission is believed to be dominated by a thermal, geometrically […]


Continue.. The high polarisation of the X-rays from the Black Hole X-ray Binary 4U 1630-47 challenges standard thin accretion disc scenario

Layer 5a Corticostriatal Projection Neurons are Selectively Vulnerable in Huntington’s Disease

Kavli Affiliate: Nathaniel Heintz | Authors: Christina Pressl, Kert Mätlik, Laura Kus, Paul Darnell, Ji-Dung Luo, Alison R Weiss, William Liguore, Thomas Carroll, David A Davis, Jodi McBride and Nathaniel Heintz | Summary: The properties of the cell types that are most vulnerable in the Huntington’s disease (HD) cortex, the nature of somatic CAG expansion […]


Continue.. Layer 5a Corticostriatal Projection Neurons are Selectively Vulnerable in Huntington’s Disease

Cell Type Specific CAG Repeat Expansion and Toxicity of Mutant Huntingtin in Human Striatal and Cerebellar Cell Types

Kavli Affiliate: Nathaniel Heintz | Authors: Kert Mätlik, Matthew Baffuto, Laura Kus, David A Davis, Matthew R Paul, Thomas S Carroll and Nathaniel Heintz | Summary: Tissue-specific somatic expansion of the mutant Huntingtin (mHTT) CAG tract and regional degeneration of the brain are key features of Huntington’s disease (HD). However, the relationships between somatic CAG […]


Continue.. Cell Type Specific CAG Repeat Expansion and Toxicity of Mutant Huntingtin in Human Striatal and Cerebellar Cell Types

Insights for disease modeling from single cell transcriptomics of iPSC-derived Ngn2-induced neurons and astrocytes across differentiation time and co-culture

Kavli Affiliate: Loyal Goff | Authors: Debamitra Das, Shreyash Sonthalia, Genevieve G Stein-O’Brien, Marah Wahbeh, Kyra Feuer, Loyal Goff, Carlo Colantuoni, Vasiliki Machairaki and Dimitrios Avramopoulos | Summary: Trans-differentiation of human induced pluripotent stem cells into neurons via Ngn2-induction (hiPSC-N) has become an efficient system to quickly generate neurons for disease modeling and in vitro […]


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A spatially resolved single cell genomic atlas of the adult human breast

Kavli Affiliate: Robert Edwards | Authors: Tapsi Kumar, Kevin Nee, Runmin Wei, Siyuan He, Quy Nguyen, Shanshan Bai, Kerrigan Blake, Maren Pein, Yanwen Gong, Emi Sei, Min Hu, Anna Casasent, Aatish Thennavan, Jianzhuo Li, Tuan Tran, Ken Chen, Benedikt Nilges, Nachiket Kashikar, Oliver Braubach, Bassem Cheikh, Nadya Nikulina, Hui Chen, Mediate Teshome, Brian Menegaz, Huma […]


Continue.. A spatially resolved single cell genomic atlas of the adult human breast