Ventral CA1 Population Codes for Anxiety

Kavli Affiliate: Stefano Fusi | Authors: Sean Chih-Hsiung Lim, Stefano Fusi and Rene Hen | Summary: The ventral hippocampus is a critical node in the distributed brain network that controls anxiety. Using miniature microscopy and calcium imaging, we recorded ventral CA1 (vCA1) neurons in freely moving mice as they explored variants of classic behavioral assays […]


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Dysregulation of astrocyte-secreted pleiotrophin contributes to neuronal structural and functional phenotypes in Down Syndrome

Kavli Affiliate: Nicola Allen | Authors: Ashley N Brandebura, Quinn N Asbell, Mariel Kristine B Micael and Nicola J Allen | Summary: Neuronal dendrite structure and synapse formation is tightly regulated during development to promote proper connectivity. Astrocyte-secreted proteins act as guidance and pro-synaptogenic factors, and astrocyte protein secretion is dysregulated in neurodevelopmental disorders with […]


Continue.. Dysregulation of astrocyte-secreted pleiotrophin contributes to neuronal structural and functional phenotypes in Down Syndrome

Using a function-first “scout fragment”-based approach to develop allosteric covalent inhibitors of conformationally dynamic helicase mechanoenzymes

Kavli Affiliate: Michael Miller, Ekaterina V. Vinogradova | Authors: Jared R Ramsey, Patrick M M Shelton, Tyler K. Heiss, Paul Dominic B Olinares, Lauren E Vostal, Heather Soileau, Michael Grasso, Sara Warrington, Stephanie Adaniya, Michael Miller, Shan Sun, David J Huggins, Robert W Myers, Brian T Chait, Ekaterina V Vinogradova and Tarun M Kapoor | […]


Continue.. Using a function-first “scout fragment”-based approach to develop allosteric covalent inhibitors of conformationally dynamic helicase mechanoenzymes

Small-scale signatures of primordial non-Gaussianity in k-Nearest Neighbour cumulative distribution functions

Kavli Affiliate: Tom Abel | First 5 Authors: William R. Coulton, Tom Abel, Arka Banerjee, , | Summary: Searches for primordial non-Gaussianity in cosmological perturbations are a key means of revealing novel primordial physics. However, robustly extracting signatures of primordial non-Gaussianity from non-linear scales of the late-time Universe is an open problem. In this paper, […]


Continue.. Small-scale signatures of primordial non-Gaussianity in k-Nearest Neighbour cumulative distribution functions

Perfect Coulomb drag in a dipolar excitonic insulator

Kavli Affiliate: Jie Shan | First 5 Authors: Phuong X. Nguyen, Liguo Ma, Raghav Chaturvedi, Kenji Watanabe, Takashi Taniguchi | Summary: Excitonic insulators (EIs), arising in semiconductors when the electron-hole binding energy exceeds the band gap, are a solid-state prototype for bosonic phases of matter. Unlike the charged excitations that are frozen and unable to […]


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TOI-199 b: A well-characterized 100-day transiting warm giant planet with TTVs seen from Antarctica

Kavli Affiliate: Robert F. Goeke | First 5 Authors: Melissa J. Hobson, Trifon Trifonov, Thomas Henning, Andrés Jordán, Felipe Rojas | Summary: We present the spectroscopic confirmation and precise mass measurement of the warm giant planet TOI-199 b. This planet was first identified in TESS photometry and confirmed using ground-based photometry from ASTEP in Antarctica […]


Continue.. TOI-199 b: A well-characterized 100-day transiting warm giant planet with TTVs seen from Antarctica

TOI-199 b: A well-characterized 100-day transiting warm giant planet with TTVs seen from Antarctica

Kavli Affiliate: Robert F. Goeke | First 5 Authors: Melissa J. Hobson, Trifon Trifonov, Thomas Henning, Andrés Jordán, Felipe Rojas | Summary: We present the spectroscopic confirmation and precise mass measurement of the warm giant planet TOI-199 b. This planet was first identified in TESS photometry and confirmed using ground-based photometry from ASTEP in Antarctica […]


Continue.. TOI-199 b: A well-characterized 100-day transiting warm giant planet with TTVs seen from Antarctica

Manifestly covariant variational principle for gauge theories of gravity

Kavli Affiliate: Anthony Lasenby | First 5 Authors: Michael Hobson, Anthony Lasenby, Will Barker, , | Summary: A variational principle for gauge theories of gravity is presented, which maintains manifest covariance under the symmetries to which the action is invariant, throughout the calculation of the equations of motion and conservation laws. This is performed by […]


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Clump-scale Gas Infall in High-mass Star Formation: a Multi-transition View with JCMT HCN (4–3) Mapping

Kavli Affiliate: Ke Wang | First 5 Authors: Fengwei Xu, Ke Wang, Yuxin He, Jingwen Wu, Lei Zhu | Summary: Gas infall motions play a crucial role in high-mass star formation and are characterized by observable signatures in the form of blue-shifted asymmetric spectral line profiles ("blue profiles"). However, the connection between blue profiles and […]


Continue.. Clump-scale Gas Infall in High-mass Star Formation: a Multi-transition View with JCMT HCN (4–3) Mapping