Mechanisms underlying reshuffling of visual responses by optogenetic stimulation in mice and monkeys

Kavli Affiliate: John Reynolds, Kenneth Miller | Authors: Alessandro Sanzeni, Agostina Palmigiano, Tuan H Nguyen, Junxiang Luo, Jonathan J Nassi, John H Reynolds, Mark H Histed, Kenneth D Miller and Nicolas Brunel | Summary: The ability to observe the response of neural circuits to controlled optogenetic perturbations opens an unprecedented window into the mechanisms governing […]


Continue.. Mechanisms underlying reshuffling of visual responses by optogenetic stimulation in mice and monkeys

Rewiring Dynamics of Functional Connectome in Motor Cortex during Motor Skill Learning

Kavli Affiliate: Takaki Komiyama | Authors: Saber Meamardoost, Eunjung Hwang, Mahasweta Bhattacharya, Chi Ren, Linbing Wang, Claudia Mewes, Ying Zhang, Takaki Komiyama and Rudiyanto Gunawan | Summary: The brain’s connectome continually rewires throughout the life of an organism. In this study, we sought to elucidate the operational principles of such rewiring by analyzing the functional […]


Continue.. Rewiring Dynamics of Functional Connectome in Motor Cortex during Motor Skill Learning

The spatial distribution and temporal trends of livestock damages caused by wolves in Europe

Kavli Affiliate: Jose Suarez Lopez | Authors: Liam Singer, Xenia Wietlisbach, Raffael Hickisch, Eva Maria Schoell, Angela Van den Broek, Manon Désalme, Koen Driesen, Mari Lyly, Francesca Marucco, Miroslav Kutal, Nives Pagon, Cristian Remus Papp, Paraskevi Milioni, Remigijus Uzdras, Ilgvars Zihmanis, Fridolin Zimmermann, Katrina Marsden, Klaus Hackländer, José Vicente López-Bao, Sybille Klenzendorf and Daniel Wegmann […]


Continue.. The spatial distribution and temporal trends of livestock damages caused by wolves in Europe

Large-scale capture of hidden fluorescent labels for training generalizable markerless motion capture models

Kavli Affiliate: Eiman Azim | Authors: Daniel J Butler, Alexander P Keim, Shantanu Ray and Eiman Azim | Summary: Recent advances in deep learning-based markerless pose estimation have dramatically improved the scale and ease with which body landmarks can be tracked in studies of animal behavior. However, pose estimation for animals in a laboratory setting […]


Continue.. Large-scale capture of hidden fluorescent labels for training generalizable markerless motion capture models

Targeting C5aR1 signaling reduced neutrophil extracellular traps and ameliorates COVID-19 pathology

Kavli Affiliate: Gabriel Silva | Authors: Bruna M. Silva, Flavio Protasio Veras, Giovanni Gomes, Seppe Cambier, Gabriel Silva, Andreza Quadros, Diego Caetite, Daniele Nascimento, Camila Silva, Juliana Silva, Samara Damasceno, Ayda Schneider, Fabio Beretta, Sabrina Batah, Icaro Castro, Isadora Paiva, Tamara Rodrigues, Ana C G Salina, Ronaldo Martins, Guilherme Cebinelli, Naira Bibo, Daniel Jorge, Helder […]


Continue.. Targeting C5aR1 signaling reduced neutrophil extracellular traps and ameliorates COVID-19 pathology

Global worming: massive invasion of North America by earthworms revealed

Kavli Affiliate: John Reynolds | Authors: Jerome Mathieu, John Warren Reynolds, Carlos Fragoso and Elizabeth Hadly | Summary: Human activities cause major ecological changes by reshuffling the spatial distribution of species. The extent to which this process affects belowground biota is a critical issue because soil organisms play a key role in ecosystem functioning and […]


Continue.. Global worming: massive invasion of North America by earthworms revealed

Cortical ripples during NREM sleep and waking in humans

Kavli Affiliate: Eric Halgren | Authors: Charles W Dickey, Ilya A Verzhbinsky, Xi Jiang, Burke Q Rosen, Sophie Kajfez, Emad N Eskandar, Jorge Gonzalez-Martinez, Sydney S Cash and Eric Halgren | Summary: Hippocampal ripples index the reconstruction of spatiotemporal neuronal firing patterns essential for the consolidation of memories in the cortex during non-rapid eye movement […]


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A Generalized Reinforcement Learning-Based Deep Neural Network (GRL-DNN) Agent Model for Diverse Cognitive Constructs

Kavli Affiliate: Jyoti Mishra | Authors: Sandeep Sathyanandan Nair, Vignayanandam Ravindernath Muddapu, Vigneswaran C, Pragathi Priyadharsini Balasubramani, Jyoti Mishra, Dhaskshin S Ramanathan and V Srinivasa Chakravarthy | Summary: Human cognition is characterized by a wide range of capabilities including goal-oriented selective attention, distractor suppression, decision making, response inhibition, and working memory. Much research has focused […]


Continue.. A Generalized Reinforcement Learning-Based Deep Neural Network (GRL-DNN) Agent Model for Diverse Cognitive Constructs

Phencyclidine and methamphetamine cause cognitive deficits by changing pyramidal neuron transmitter identity in the prefrontal cortex

Kavli Affiliate: Nicholas Spitzer | Authors: Marta Pratelli, Arth Thaker, Huiquan Li, Swetha Godavarthi and Nicholas C. Spitzer | Summary: Decreased cognitive ability is a major consequence of exposure to drugs of abuse, but the underlying neuroplastic changes have been elusive. We show that both phencyclidine and methamphetamine cause a population of prelimbic pyramidal neurons […]


Continue.. Phencyclidine and methamphetamine cause cognitive deficits by changing pyramidal neuron transmitter identity in the prefrontal cortex

Multimodal monitoring of human cortical organoids implanted in mice using transparent graphene microelectrodes reveal functional connection between organoid and mouse visual cortex

Kavli Affiliate: Fred Gage | Authors: Madison Wilson, Martin Thunemann, Xin Liu, Yichen Lu, Francesca Puppo, Jason Adams, Jeong-Hoon Kim, Donald Pizzo, Srdjan Djurovic, Ole Andreassen, Abed Mansour, Fred H. Gage, Alysson R Muotri, Anna Devor and Duygu Kuzum | Summary: Human cortical organoids, three-dimensional neuronal cell cultures derived from human induced pluripotent stem cells, […]


Continue.. Multimodal monitoring of human cortical organoids implanted in mice using transparent graphene microelectrodes reveal functional connection between organoid and mouse visual cortex