Kavli Affiliate: Ethan Bier | Authors: Leonardo Lima, Mateus Berni, Jamile Mota, Daniel Bressan, Alison Julio, Robson Cavalcante, Vanessa Macias, Zhiqian Li, Jason L. Rasgon, Ethan Bier and Helena Marcolla Araujo | Summary: Rhodnius prolixus is currently the model vector of choice for studying Chagas disease transmission, a debilitating disease caused by Trypanosoma cruzi parasites. […]
Kavli Affiliate: Gabriel Silva | Authors: Marcela Trevenzoli Miranda, Luciano Pereira, Gabriel Silva Pires, Xinyi Guan, Luciano Melo Silva, Swetlana Kreinert, Eduardo Caruso Machado, Steven Jansen and Rafael Ribeiro | Summary: Considerable progress has been made in understanding the mechanisms of embolism formation based on the pneumatic method, which relies on gas discharge measurements. Here, […]
Kavli Affiliate: Wesley Thompson | Authors: Rong Zablocki, Bohan Xu, Chun-Chieh Fan and Wesley K. Thompson | Summary: Here we present a development of the novel Bayesian Regularized and Anotation-Informed Integrative Analysis of Cognition (BRAINIAC) model. BRAINIAC allows for both estimation of total variance explained by all features for a given cognitive phenotype, as well […]
Kavli Affiliate: Andrea Hasenstaub | Authors: David A. McCormick, Yousheng Shu and Andrea R Hasenstaub | Summary: The ventral pallidum (VP) contains GABA and glutamate (Glut) neurons projecting to ventral tegmental area (VTA) whose stimulation drives approach and avoidance, respectively. Yet little is known about the cell-type-specific mechanisms by which VP projections to VTA drive […]
Kavli Affiliate: V. S. Ramachandran | Authors: Alba Pacheco-Moreno, Anita Bollmann-Giolai, Govind Chandra, Paul Brett, Jack Davies, Owen Thornton, Philip Poole, Vinoy Ramachandran, James Brown, Paul Nicholson, Chris Ridout, Sarah DeVos and Jacob G. Malone | Summary: Plant associated microbes play vital roles in promoting plant growth and health, with plants secreting root exudates into […]
Kavli Affiliate: Terrence Sejnowski | Authors: Guadalupe C. Garcia, Kavya Gupta, Thomas M. Bartol, Jr., Terrence J. Sejnowski and Padmini Rangamani | Summary: Life is based on energy conversion. In particular, in the nervous system significant amounts of energy are needed to maintain synaptic transmission and homeostasis. To a large extent, neurons depend on oxidative […]
Kavli Affiliate: Gabriel Silva | Authors: Gabriel Silva Santos, Samuel J L Gascoigne, Andre Tavares Correia Dias, Maja Kajin and Rob Salguero-Gomez | Summary: The Demographic Buffering Hypothesis (DBH) predicts that natural selection reduces the temporal fluctuations in demographic processes (such as survival, development, and reproduction), due to their negative impacts on population dynamics. However, […]
Kavli Affiliate: Dhakshin Ramanathan | Authors: Miranda Francoeur Koloski, Christopher M O’Hearn, Michelle Frankot, Lauren P Giesler, Dhakshin S Ramanathan and Cole Vonder Haar | Summary: Traumatic brain injury (TBI) affects a large population, resulting in severe cognitive impairments. Although cognitive rehabilitation is an accepted treatment for some deficits, studies in patients are limited in […]
Kavli Affiliate: Timothy Brown | Authors: Kristian Davidsen, Jonathan S Marvin, Abhi Aggarwal, Timothy A Brown and Lucas B Sullivan | Summary: Intracellular levels of the amino acid aspartate are responsive to changes in metabolism in mammalian cells and can correspondingly alter cell function, highlighting the need for robust tools to measure aspartate abundance. However, […]
Kavli Affiliate: Timothy Brown, Anders Dale | Authors: Carolina Makowski, Timothy T Brown, Weiqi Zhao, Donald J Hagler, Pravesh Parekh, Hugh Garavan, Thomas E Nichols, Terry L Jernigan and Anders M Dale | Summary: Magnetic resonance imaging (MRI) has been a popular and useful non-invasive method to map patterns of brain structure and function to […]