The Limiting Speed of the Bacterial Flagellar Motor

Kavli Affiliate: Richard Berry | Summary:Recent experiments on the bacterial flagellar motor have shown that the structure of this nanomachine, which drives locomotion in a wide range of bacterial species, is more dynamic than previously believed. Specifically, the number of active torque-generating units (stators) was shown to vary across applied loads. This finding invalidates the […]


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Mechanics of torque generation in the bacterial flagellar motor

Kavli Affiliate: Richard Berry | Summary:The bacterial flagellar motor (BFM) is responsible for driving bacterial locomotion and chemotaxis, fundamental processes in pathogenesis and biofilm formation. In the BFM, torque is generated at the interface between transmembrane proteins (stators) and a rotor. It is well-established that the passage of ions down a transmembrane gradient through the […]


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Steps and bumps: precision extraction of discrete states of molecular machines using physically-based, high-throughput time series analysis

Kavli Affiliate: Richard Berry | Summary:We report new statistical time-series analysis tools providing significant improvements in the rapid, precision extraction of discrete state dynamics from large databases of experimental observations of molecular machines. By building physical knowledge and statistical innovations into analysis tools, we demonstrate new techniques for recovering discrete state transitions buried in highly […]


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Applying coupon-collecting theory to computer-aided assessments

Kavli Affiliate: Carol Robinson | Summary:Computer-based tests with randomly generated questions allow a large number of different tests to be generated. Given a fixed number of alternatives for each question, the number of tests that need to be generated before all possible questions have appeared is surprisingly low. | Search Query: arXiv Query: search_query=au:”Robinson Carol”&id_list=&start=0&max_results=10Read […]


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