Elucidating the mechanism of step-emulsification

Kavli Affiliate: David A. Weitz | First 5 Authors: Andrea Montessori, Marco Lauricella, Sauro Succi, Elad Stolovicki, David A. Weitz | Summary: Three-dimensional, time-dependent direct simulations of step emulsification micro-devices highlight two essential mechanisms for droplet formation: first, the onset of an adverse pressure gradient driving a back-flow of the continuous phase from the external […]


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Automated Measurements of Key Morphological Features of Human Embryos for IVF

Kavli Affiliate: Daniel Needleman | First 5 Authors: Brian D. Leahy, Won-Dong Jang, Helen Y. Yang, Robbert Struyven, Donglai Wei | Summary: A major challenge in clinical In-Vitro Fertilization (IVF) is selecting the highest quality embryo to transfer to the patient in the hopes of achieving a pregnancy. Time-lapse microscopy provides clinicians with a wealth […]


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A model for the fragmentation kinetics of crumpled thin sheets

Kavli Affiliate: Shmuel M. Rubinstein | First 5 Authors: Jovana Andrejevic, Lisa M. Lee, Shmuel M. Rubinstein, Chris H. Rycroft, | Summary: As a confined thin sheet crumples, it spontaneously segments into flat facets delimited by a network of ridges. Despite the apparent disorder of this process, statistical properties of crumpled sheets exhibit striking reproducibility. […]


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Scaling down an insect-size microrobot, HAMR-VI into HAMR-Jr

Kavli Affiliate: Robert J. Wood | First 5 Authors: Kaushik Jayaram, Jennifer Shum, Samantha Castellanos, E. Farrell Helbling, Robert J. Wood | Summary: Here we present HAMR-Jr, a SI{22.5}{millimeter}, SI{320}{milligram} quadrupedal microrobot. With eight independently actuated degrees of freedom, HAMR-Jr is, to our knowledge, the most mechanically dexterous legged robot at its scale and is […]


Continue.. Scaling down an insect-size microrobot, HAMR-VI into HAMR-Jr

Scaling down an insect-size microrobot, HAMR-VI into HAMR-Jr

Kavli Affiliate: Robert J. Wood | First 5 Authors: Kaushik Jayaram, Jennifer Shum, Samantha Castellanos, E. Farrell Helbling, Robert J. Wood | Summary: Here we present HAMR-Jr, a SI{22.5}{millimeter}, SI{320}{milligram} quadrupedal microrobot. With eight independently actuated degrees of freedom, HAMR-Jr is, to our knowledge, the most mechanically dexterous legged robot at its scale and is […]


Continue.. Scaling down an insect-size microrobot, HAMR-VI into HAMR-Jr

Probing and manipulating embryogenesis via nanoscale thermometry and temperature control

Kavli Affiliate: Daniel Needleman | First 5 Authors: Joonhee Choi, Hengyun Zhou, Renate Landig, Hai-Yin Wu, Xiaofei Yu | Summary: Understanding the coordination of cell division timing is one of the outstanding questions in the field of developmental biology. One active control parameter of the cell cycle duration is temperature, as it can accelerate or […]


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Effect of surface chemistry on incorporation of nanoparticles within calcite single crystals

Kavli Affiliate: Joanna Aizenberg | First 5 Authors: Giulia Magnabosco, Iryna Polishchuk, Francesco Palomba, Enrico Rampazzo, Luca Prodi | Summary: Inclusion of additives into calcite crystals allows one to embed non-native proprieties into the inorganic matrix and obtain new functional materials. Up to now, few parameters have been taken into account to evaluate the efficiency […]


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It’s easy to fool yourself: Case studies on identifying bias and confounding in bio-medical datasets

Kavli Affiliate: Michael Brenner | First 5 Authors: Subhashini Venugopalan, Arunachalam Narayanaswamy, Samuel Yang, Anton Geraschenko, Scott Lipnick | Summary: Confounding variables are a well known source of nuisance in biomedical studies. They present an even greater challenge when we combine them with black-box machine learning techniques that operate on raw data. This work presents […]


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Large depth-of-field tracking of colloidal spheres in holographic microscopy by modeling the objective lens

Kavli Affiliate: Vinothan Manoharan | First 5 Authors: Brian Leahy, Ronald Alexander, Caroline Martin, Solomon Barkley, Vinothan Manoharan | Summary: Holographic microscopy has developed into a powerful tool for 3D particle tracking, yielding nanometer-scale precision at high frame rates. However, current particle tracking algorithms ignore the effect of the microscope objective on the formation of […]


Continue.. Large depth-of-field tracking of colloidal spheres in holographic microscopy by modeling the objective lens