Kavli Affiliate: Hana El-Samad | Authors: Matthew S Kim, Hersh K Bhargava, Gavin E Shavey, Wendell A Lim, Hana El-Samad and Andrew H Ng | Summary: Chimeric antigen receptor (CAR) T cells have made a tremendous impact in the clinic, but potent signaling through the CAR can be detrimental to treatment safety and efficacy. The […]
Kavli Affiliate: Jing Wang | First 5 Authors: Dingquan Li, Kede Ma, Jing Wang, Ge Li, | Summary: The Geometry-based Point Cloud Compression (G-PCC) has been developed by the Moving Picture Experts Group to compress point clouds. In its lossy mode, the reconstructed point cloud by G-PCC often suffers from noticeable distortions due to the […]
Kavli Affiliate: Feng Wang | First 5 Authors: Feng Wang, Renfang Wang, Bo Yang, Hong Qiu, | Summary: Low-Dose computer tomography (LDCT) is an ideal alternative to reduce radiation risk in clinical applications. Although supervised-deep-learning-based reconstruction methods have demonstrated superior performance compared to conventional model-driven reconstruction algorithms, they require collecting massive pairs of low-dose and […]
Kavli Affiliate: Timothy A. Ryan, Timothy Brown | Authors: Ryan J Farrell, Kirsten G Bredvik, Michael Blake Hoppa, S Thomas Hennegan, Timothy A Brown and Timothy A Ryan | Summary: The endoplasmic reticulum (ER) is an important regulator of Ca2+ in cells and dysregulation of ER calcium homeostasis can lead to numerous pathologies. Understanding how […]
Kavli Affiliate: Xiang Zhang | First 5 Authors: Zongyu Wu, Hongcheng Gao, Yueze Wang, Xiang Zhang, Suhang Wang | Summary: Text-to-Image (T2I) models have shown great performance in generating images based on textual prompts. However, these models are vulnerable to unsafe input to generate unsafe content like sexual, harassment and illegal-activity images. Existing studies based […]
Kavli Affiliate: Lars Bildsten | First 5 Authors: Logan J. Prust, Hila Glanz, Lars Bildsten, Hagai B. Perets, Friedrich K. Roepke | Summary: We carry out three-dimensional computations of the accretion rate onto an object (of size $R_{rm sink}$ and mass $m$) as it moves through a uniform medium at a subsonic speed $v_{infty}$. The […]
Kavli Affiliate: Li Zhao | Authors: Xin Hou, Yong He, Pan Fang, Shi-Qiang Mei, Zan Xu, Wei-Chen Wu, Jun-Hua Tian, Shun Zhang, Zhen-Yu Zeng, Qin-Yu Gou, Gen-Yang Xin, Shi-Jia Le, Yin-Yue Xia, Yu-Lan Zhou, Feng-Ming Hui, Yuan-Fei Pan, John-Sebastian Eden, Zhao-Hui Yang, Chong Han, Yue-Long Shu, Deyin Guo, Jun Li, Edward C Holmes, Zhao-Rong Li […]
Kavli Affiliate: Michael W. Young | Authors: Waruna Thotamune, Sithurandi Ubeysinghe, Kendra Kumar Shrestha, Mahmoud Elhusse Mostafa, Michael C Young and Ajith Karunarathne | Summary: Beta-adrenergic receptors (βARs) are G protein-coupled receptors (GPCRs) that mediate catecholamine-induced stress responses, such as heart rate increase and bronchodilation. In addition to signals from the cell surface, βARs also […]
Kavli Affiliate: Dheeraj R. Pasham | First 5 Authors: Dheeraj R. Pasham, Eric R. Coughlin, Michal Zajacek, Itai Linial, Petra Sukova | Summary: Quasi-periodic Eruptions (QPEs) represent a novel class of extragalactic X-ray transients that are known to repeat at roughly regular intervals of a few hours to days. Their underlying physical mechanism is a […]
Kavli Affiliate: Dheeraj R. Pasham | First 5 Authors: Dheeraj R. Pasham, Michal Zajacek, C. J. Nixon, Eric R. Coughlin, Marzena Sniegowska | Summary: An accretion disk formed around a supermassive black hole (SMBH) after it disrupts a star is expected to be initially misaligned with respect to the black hole’s equatorial plane. This misalignment […]