Hierarchical Inference of the Lensing Convergence from Photometric Catalogs with Bayesian Graph Neural Networks

Kavli Affiliate: Philip J. Marshall | First 5 Authors: Ji Won Park, Simon Birrer, Madison Ueland, Miles Cranmer, Adriano Agnello | Summary: We present a Bayesian graph neural network (BGNN) that can estimate the weak lensing convergence ($kappa$) from photometric measurements of galaxies along a given line of sight. The method is of particular interest […]


Continue.. Hierarchical Inference of the Lensing Convergence from Photometric Catalogs with Bayesian Graph Neural Networks

Hierarchical Inference of the Lensing Convergence from Photometric Catalogs with Bayesian Graph Neural Networks

Kavli Affiliate: Aaron Roodman | First 5 Authors: Ji Won Park, Simon Birrer, Madison Ueland, Miles Cranmer, Adriano Agnello | Summary: We present a Bayesian graph neural network (BGNN) that can estimate the weak lensing convergence ($kappa$) from photometric measurements of galaxies along a given line of sight. The method is of particular interest in […]


Continue.. Hierarchical Inference of the Lensing Convergence from Photometric Catalogs with Bayesian Graph Neural Networks

Direct Cortical Inputs to Hippocampal Area CA1 Transmit Complementary Signals for Goal-directed Navigation

Kavli Affiliate: Attila Losonczy | Authors: John C Bowler and Attila Losonczy | Summary: Summary The entorhinal cortex (EC) is central to the brain’s navigation system. Its subregions are conventionally thought to compute dichotomous representations for spatial processing: medial entorhinal cortex (MEC) provides a global spatial map, while lateral entorhinal cortex (LEC) encodes specific sensory […]


Continue.. Direct Cortical Inputs to Hippocampal Area CA1 Transmit Complementary Signals for Goal-directed Navigation

The HCN1 hyperpolarization-activated cyclic nucleotide-gated channel enhances evoked GABA release from parvalbumin positive interneurons

Kavli Affiliate: Steven Siegelbaum | Authors: Tobias Bock, Eric W Buss, Olivia M Lofaro, Felix W Leroy, Bina Santoro and Steven A Siegelbaum | Summary: Abstract Hyperpolarization-activated, cyclic nucleotide-gated (HCN) channels generate the cationic Ih current in neurons and regulate the excitability of neuronal networks. The function of HCN channels depends, in part, on their […]


Continue.. The HCN1 hyperpolarization-activated cyclic nucleotide-gated channel enhances evoked GABA release from parvalbumin positive interneurons

Converting an allocentric goal into an egocentric steering signal

Kavli Affiliate: Gaby Maimon | Authors: Peter Mussells Pires, L F Abbott and Gaby Maimon | Summary: Abstract Neuronal signals relevant for spatial navigation have been described in many species[1-12], however, a circuit-level understanding of how such signals interact to guide behaviour is lacking. Here we characterize a neuronal circuit in the Drosophila central complex […]


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Tautomer-specific deacylation and Ω-loop flexibility explain carbapenem-hydrolyzing, broad-spectrum activity of the KPC-2 β-lactamase

Kavli Affiliate: Michael Beer | Authors: Catherine L Tooke, Philip Hinchliffe, Michael Beer, Kirill Zinovjev, Charlie K Colenso, Christopher J Schofield, Adrian J Mulholland and James Spencer | Summary: Abstract KPC-2 (Klebsiella pneumoniae carbapenemase-2) is a globally disseminated serine-β-lactamase (SBL) responsible for extensive β-lactam antibiotic resistance in Gram-negative pathogens. SBLs inactivate β-lactams via a mechanism […]


Continue.. Tautomer-specific deacylation and Ω-loop flexibility explain carbapenem-hydrolyzing, broad-spectrum activity of the KPC-2 β-lactamase

Inflammation-Responsive Micellar Nanoparticles from Degradable Polyphosphoramidates for Targeted Delivery to Myocardial Infarction

Kavli Affiliate: Karen Christman | Authors: Yifei Liang, Holly Sullivan, Kendal Carrow, Joanna Korpanty, Kendra Worthington, Colin Luo, Karen L Christman and Nathan C Gianneschi | Summary: ABSTRACT Nanoparticles that undergo a localized morphology change to target areas of inflammation have been previously developed but are limited by their lack of biodegradability. In this paper, […]


Continue.. Inflammation-Responsive Micellar Nanoparticles from Degradable Polyphosphoramidates for Targeted Delivery to Myocardial Infarction

Circuit dissection and functional validation of a cross-species emotional biomarker

Kavli Affiliate: Edward Chang, Vikaas Sohal | Authors: Adam Jackson, Josh Cohen, Aarron Phensy, Edward F Chang, Heather Dawes and Vikaas Sohal | Summary: ABSTRACT Emotional responses arise from limbic circuits including the hippocampus and amygdala. In the human brain, beta-frequency communication between these structures correlates with self-reported mood and anxiety. However, both the mechanism […]


Continue.. Circuit dissection and functional validation of a cross-species emotional biomarker

A Multi-Qubit Quantum Gate Using the Zeno Effect

Kavli Affiliate: Birgitta Whaley | First 5 Authors: Philippe Lewalle, Leigh S. Martin, Emmanuel Flurin, Song Zhang, Eliya Blumenthal | Summary: The Zeno effect, in which repeated observation freezes the dynamics of a quantum system, stands as an iconic oddity of quantum mechanics. When a measurement is unable to distinguish between states in a subspace, […]


Continue.. A Multi-Qubit Quantum Gate Using the Zeno Effect

A Multi-Qubit Quantum Gate Using the Zeno Effect

Kavli Affiliate: Birgitta Whaley | First 5 Authors: Philippe Lewalle, Leigh S. Martin, Emmanuel Flurin, Song Zhang, Eliya Blumenthal | Summary: The Zeno effect, in which repeated observation freezes the dynamics of a quantum system, stands as an iconic oddity of quantum mechanics. When a measurement is unable to distinguish between states in a subspace, […]


Continue.. A Multi-Qubit Quantum Gate Using the Zeno Effect