Cooling fast and slow: Characterising the effects of vitrification in cryo-EM and the subsequent recovery of equilibrium populations

Posted by dbos UCSD / Salk

Kavli Affiliate: Robert E. Clark | Authors: Robert Clark, Louis G. Smith, Matthew P. Leighton, Ryan J. Szukalo, Syma Khalid, Pablo G. Debenedetti, Pilar Cossio, Miro A. Astore and Sonya M. Hanson | Summary: Single-particle cryogenic electron microscopy (cryo-EM) has enabled near-atomic resolution structure determination of diverse biomolecules. Because the high vacuum required for electron […]


Continue.. Cooling fast and slow: Characterising the effects of vitrification in cryo-EM and the subsequent recovery of equilibrium populations

A human specific CCG repeat in the RBFOX1 promoter is implicated in speech and autism

Posted by dbos Rockefeller

Kavli Affiliate: Erich Jarvis | Authors: Chul Lee, Matthew H Davenport and Erich D Jarvis | Summary: Human speech likely arose from regulatory changes for speech-related brain regions, yet causal variants and mechanisms remain unclear. RBFOX1 is a prime candidate, showing specialized expression in vocal learning circuits of human and zebra finch brains and carrying […]


Continue.. A human specific CCG repeat in the RBFOX1 promoter is implicated in speech and autism

Synovial transcriptional clusters link cartilage degeneration to cell-type-specific gene expression in knee osteoarthritis

Posted by dbos Rockefeller

Kavli Affiliate: Robert B. Darnell | Authors: Michael R. Mazzucco, Bella Mehta, Jenelys Ruiz-Ortiz, Caryn Hale, Fuadur Omi, Purva Singh, Ruoxi Yuan, Samantha Lessard, Eun Kyung Song, Mengrui Zhang, Shady Younis, William H. Robinson, Daniel Ramirez, Edward DiCarlo, Wei Wang, Thomas Carroll, Jose Rodriguez, Peter Sculco, Xiaoshun Li, YiYuan Wu, Robert B. Darnell, Martin Lotz, […]


Continue.. Synovial transcriptional clusters link cartilage degeneration to cell-type-specific gene expression in knee osteoarthritis

Itô tracers: continuous-trajectory Lagrangian particles for Eulerian hydrodynamics

Posted by klaurent Stanford

Kavli Affiliate: Tom Abel | Summary:Lagrangian tracer particles have long been used to track the history of individual gas parcels in hydrodynamical codes. Particles advected by the cell-centered velocity carry no representation of underlying numerical diffusion, and thus exhibit systematic bias. The Monte-Carlo (MC) tracer resolves this with discrete probabilistic cell-to-cell, flux-based jumps, at the […]


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IXPE Polarizations of the Lighthouse Pulsar, Trail, and Filament

Posted by klaurent Stanford

Kavli Affiliate: Roger Romani | Summary:The Lighthouse pulsar (PSR J1101$-$6101) sports a bright X-ray trail and filament. The synchrotron emission from both structures is expected to be polarized, with electric vector position angle (EVPA) perpendicular to the magnetic field direction and polarization degree (PD) indicating the local degree of magnetic turbulence. We present a 1 […]


Continue.. IXPE Polarizations of the Lighthouse Pulsar, Trail, and Filament

IXPE Polarizations of the Lighthouse Pulsar, Trail, and Filament

Posted by klaurent Stanford

Kavli Affiliate: Roger Romani | Summary:The Lighthouse pulsar (PSR J1101$-$6101) sports a bright X-ray trail and filament. The synchrotron emission from both structures is expected to be polarized, with electric vector position angle (EVPA) perpendicular to the magnetic field direction and polarization degree (PD) indicating the local degree of magnetic turbulence. We present a 1 […]


Continue.. IXPE Polarizations of the Lighthouse Pulsar, Trail, and Filament

Strain engineering of Andreev spin qubits in Germanium

Posted by klaurent Delft

Kavli Affiliate: Anton Akhmerov | Summary:Planar germanium heterostructures are promising hosts for hybrid quantum devices due to their compatibility with superconductors, low material disorder, and relaxed fabrication constraints. Also, the potentially low density of nuclear spins and strong spin-orbit interaction make germanium attractive for coherent spin physics. However, recent microwave spectroscopy experiments were unable to […]


Continue.. Strain engineering of Andreev spin qubits in Germanium

Strain engineering of Andreev spin qubits in Germanium

Posted by klaurent Delft

Kavli Affiliate: Anton Akhmerov | Summary:Planar germanium heterostructures are promising hosts for hybrid quantum devices due to their compatibility with superconductors, low material disorder, and relaxed fabrication constraints. Also, the potentially low density of nuclear spins and strong spin-orbit interaction make germanium attractive for coherent spin physics. However, recent microwave spectroscopy experiments were unable to […]


Continue.. Strain engineering of Andreev spin qubits in Germanium

Stability of Branching Multiplicities for Orthogonal Gelfand Pairs

Posted by klaurent Tokyo

Kavli Affiliate: Toshiyuki Kobayashi | Summary:We propose a structural framework for branching multiplicities in representation theory, emphasizing their behavior under variation of infinitesimal characters. For the orthogonal reductive pairs $(G,G’)$ with complexified Lie algebras $(mathfrako(n+1,mathbbC), mathfrako(n,mathbbC))$, we show that branching multiplicities are governed by universal systems of linear inequalities on the parameter space of reduced […]


Continue.. Stability of Branching Multiplicities for Orthogonal Gelfand Pairs