Mapping spatial gradients in spatial transcriptomics data with score matching

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Laurent Younes | Authors: An Wang, Donald Geman, Uthsav Chitra and Laurent Younes | Summary: Spatial transcriptomics (ST) technologies measure gene expression at thousands of locations within a two-dimensional tissue slice, enabling the study of spatial gene expression patterns. Spatial […]


Continue.. Mapping spatial gradients in spatial transcriptomics data with score matching

Tracing Structure: Shape and Centroid Deviations in 39 Strong Lensing Clusters as a Test of Cluster Formation Predictions

Kavli Affiliate: Michael McDonald | Summary:Strong lensing galaxy clusters provide a unique and powerful way to test simulation-derived structure predictions that follow from $Λ$ Cold Dark Matter ($Λ$CDM) cosmology. Specifically, the relative alignments of the dark matter (DM) halo, stars, and hot intracluster gas in these clusters offer insights into how well theoretical structure predictions […]


Continue.. Tracing Structure: Shape and Centroid Deviations in 39 Strong Lensing Clusters as a Test of Cluster Formation Predictions

Generative Models for Crystalline Materials

Kavli Affiliate: Gerbrand Ceder| Summary:Understanding structure-property relationships in materials is fundamental in condensed matter physics and materials science. Over the past few years, machine learning (ML) has emerged as a powerful tool for advancing this understanding and accelerating materials discovery. Early ML approaches primarily focused on constructing and screening large material spaces to identify promising […]


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Joint Estimation of Sea State and Vessel Parameters Using a Mass-Spring-Damper Equivalence Model

Kavli Affiliate: Peter Graham | Summary:Real-time sea state estimation is vital for applications like shipbuilding and maritime safety. Traditional methods rely on accurate wave-vessel transfer functions to estimate wave spectra from onboard sensors. In contrast, our approach jointly estimates sea state and vessel parameters without needing prior transfer function knowledge, which may be unavailable or […]


Continue.. Joint Estimation of Sea State and Vessel Parameters Using a Mass-Spring-Damper Equivalence Model

Joint Estimation of Sea State and Vessel Parameters Using a Mass-Spring-Damper Equivalence Model

Kavli Affiliate: Peter Graham | Summary:Real-time sea state estimation is vital for applications like shipbuilding and maritime safety. Traditional methods rely on accurate wave-vessel transfer functions to estimate wave spectra from onboard sensors. In contrast, our approach jointly estimates sea state and vessel parameters without needing prior transfer function knowledge, which may be unavailable or […]


Continue.. Joint Estimation of Sea State and Vessel Parameters Using a Mass-Spring-Damper Equivalence Model

The Atacama Cosmology Telescope: $B$-mode delensing with DR6 data and external tracers of large-scale structure

Kavli Affiliate: Anthony Challinor | Summary:Large-scale $B$-mode polarization of the cosmic microwave background (CMB) is a prime target for current and future experiments in search of primordial gravitational waves (PGW). With increasingly sensitive instruments being deployed, secondary $B$-modes induced by the weak gravitational lensing of CMB photons are becoming an important limitation and need to […]


Continue.. The Atacama Cosmology Telescope: $B$-mode delensing with DR6 data and external tracers of large-scale structure

Modeling Galaxy Formation in Cosmological Simulations with CRK-HACC

Kavli Affiliate: Katrin Heitmann | Summary:Self-consistently modeling baryonic effects in survey-scale cosmological simulations has become increasingly important as the diversity, precision, and statistical reach of modern observations continue to improve. The advent of exascale computing now enables a new generation of simulations that couple these physical processes across full-sky volumes with excellent statistical sampling of […]


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Gravitational waves from the late inspiral, transition, and plunge of small-mass-ratio eccentric binaries

Kavli Affiliate: Scott A. Hughes | Summary:Black hole binaries with small mass ratios will be important sources for the forthcoming Laser Interferometer Space Antenna (LISA) mission. Models of such binaries also serve as useful tools for understanding the dynamics of compact binary systems and the gravitational waves they emit. Using an eccentric Ori-Thorne procedure developed […]


Continue.. Gravitational waves from the late inspiral, transition, and plunge of small-mass-ratio eccentric binaries

Gravitational waves from the late inspiral, transition, and plunge of small-mass-ratio eccentric binaries

Kavli Affiliate: Scott A. Hughes | Summary:Black hole binaries with small mass ratios will be important sources for the forthcoming Laser Interferometer Space Antenna (LISA) mission. Models of such binaries also serve as useful tools for understanding the dynamics of compact binary systems and the gravitational waves they emit. Using an eccentric Ori-Thorne procedure developed […]


Continue.. Gravitational waves from the late inspiral, transition, and plunge of small-mass-ratio eccentric binaries

A Super-Eddington, Lensing-Magnified Quasar at $z=5.07$ observed with JWST

Kavli Affiliate: Robert Simcoe | Summary:We present JWST/NIRCam F070W and F480M imaging for a quasar at $z = 5.07$, J0025-0145, which is magnified by a foreground lensing galaxy. Existing Hubble Space Telescope (HST) imaging does not have sufficient spatial resolution to determine whether the background quasar is multiply imaged. Exploiting the sharp PSF of the […]


Continue.. A Super-Eddington, Lensing-Magnified Quasar at $z=5.07$ observed with JWST