| Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury |
Kavli Affiliate: Keri Martinowich
| Authors: Helena L Crowell, Yixing Dong, Ilaria Billato, Peiying Cai, Martin Emons, Samuel Gunz, Boyi Guo, Mengbo Li, Alexandru Mahmoud, Artür Manukyan, Hervé Pagès, Pratibha Panwar, Shreya Rao, Callum J Sargeant, Lori Shepherd Kern, Marcel Ramos, Jieran Sun, Michael Totty, Vincent J Carey, Yunshun Chen, Leonardo Collado-Torres, Shila Ghazanfar, Kasper D Hansen, Keri Martinowich, Kristen R Maynard, Ellis Patrick, Dario Righelli, Davide Risso, Simone Tiberi, Levi Waldron, Raphael Gottardo, Mark D Robinson, Stephanie C Hicks and Lukas M Weber
| Summary:
Spatial transcriptomics technologies provide spatially-resolved measurements of gene expression through assays that can either target selected genes or capture transcriptome-wide expression profiles. The complexity and variability of these technologies and their associated data necessitate multi-step workflows integrating diverse computational methods and software packages. We provide a freely accessible, open-source, continuously updated and tested online book containing reproducible code examples, datasets, and discussion about data analysis workflows for spatial omics data using Bioconductor in R, including interoperability with Python.