CSTEapp: An interactive R-Shiny application of the covariate-specific treatment effect curve for visualizing individualized treatment rule

Posted by klaurent UCAS

Kavli Affiliate: Yi Zhou | First 5 Authors: , , , , | Summary: In precision medicine, deriving the individualized treatment rule (ITR) is crucial for recommending the optimal treatment based on patients’ baseline covariates. The covariate-specific treatment effect (CSTE) curve presents a graphical method to visualize an ITR within a causal inference framework. Recent […]


Continue.. CSTEapp: An interactive R-Shiny application of the covariate-specific treatment effect curve for visualizing individualized treatment rule

Tactile responses in the mouse perirhinal cortex show invariance to physical features of the stimulus

Posted by dbos NTNU

Kavli Affiliate: Maximiliano Jose Nigro | Rejwan Hamza Farhad Salih, Luis Fernando Cobar, Francois Philippe Pauzin, Davide Zoccolan and Maximiliano Jose Nigr | Summary: Abstract Sensory processing in the cortex follows a hierarchical structure, transforming fine-grained stimulus features into abstract, invariant representations. These transformations have typically been characterised in visual pathways ranging from primary visual […]


Continue.. Tactile responses in the mouse perirhinal cortex show invariance to physical features of the stimulus

Transcriptional Interference Gates Monogenic Odorant Receptor Expression in Ants

Posted by dbos Rockefeller

Kavli Affiliate: Daniel Kronauer | Giacomo Leon Glotzer, P. Daniel H. Pastor and Daniel J. C. Kronauer | Summary: Communication is crucial to social life, and in ants, it is mediated primarily through olfaction. Ants have more odorant receptor (OR) genes than any other group of insects, generated through tandem duplications that produce large genomic […]


Continue.. Transcriptional Interference Gates Monogenic Odorant Receptor Expression in Ants

A predicted structural interactome reveals binding interference from intrinsically disordered regions

Posted by dbos Rockefeller

Kavli Affiliate: Li Zhao | Junhui Peng and Li Zhao | Summary: Proteins function through dynamic interactions with other proteins in cells, forming complex networks fundamental to cellular processes. While high-resolution and high-throughput methods have significantly advanced our understanding of how proteins interact with each other, the molecular details of many important protein-protein interactions are […]


Continue.. A predicted structural interactome reveals binding interference from intrinsically disordered regions

Single-click protocols for remote state preparation using weak coherent pulses

Posted by klaurent Delft

Kavli Affiliate: Stephanie Wehner | Summary:Remote state preparation (RSP) allows one party to remotely prepare a known quantum state on another party’s qubit using entanglement. This can be used in quantum networks to perform applications such as blind quantum computing or long-distance quantum key distribution (QKD) with quantum repeaters. Devices to perform RSP, referred to […]


Continue.. Single-click protocols for remote state preparation using weak coherent pulses

Nonstrange and strange quark matter at finite temperature within modified NJL model and protoquark stars

Posted by klaurent Peking

Kavli Affiliate: Renxin Xu | Summary:We extend the modified Nambu-Jona-Lasinio (NJL) model — incorporating exchange interactions via the Fierz transformation — to finite temperatures in both two- and three-flavor scenarios, and investigate the properties of protoquark stars in $β$-equilibrium. Our results show that increasing the strength of exchange interactions, characterized by the parameter $α$, changes […]


Continue.. Nonstrange and strange quark matter at finite temperature within modified NJL model and protoquark stars

Structure-Aware Temporal Modeling for Chronic Disease Progression Prediction

Posted by klaurent Berkeley

Kavli Affiliate: Ting Xu | First 5 Authors: Jiacheng Hu, Jiacheng Hu, , , | Summary: This study addresses the challenges of symptom evolution complexity and insufficient temporal dependency modeling in Parkinson’s disease progression prediction. It proposes a unified prediction framework that integrates structural perception and temporal modeling. The method leverages graph neural networks to […]


Continue.. Structure-Aware Temporal Modeling for Chronic Disease Progression Prediction

Jahn-Teller-like Distortion in a One-dimensional π-Conjugated Polymer

Posted by klaurent Berkeley

Kavli Affiliate: Felix Fischer | Summary:Structurally distorting low-dimensional π-conjugated systems can profoundly influence their electronic properties, but controlling such behavior in extended-width systems remains challenging. Here we demonstrate that a one-dimensional conjugated polymer, poly-(difluorenoheptalene-ethynylene) (PDFHE), undergoes a pronounced out-of-plane backbone distortion, equivalent to a spontaneous symmetry breaking (SSB) of its mirror symmetry. We synthesized PDFHE […]


Continue.. Jahn-Teller-like Distortion in a One-dimensional π-Conjugated Polymer

Jahn-Teller-like Distortion in a One-dimensional π-Conjugated Polymer

Posted by klaurent Berkeley

Kavli Affiliate: Michael F. Crommie | First 5 Authors: Ziyi Wang, Ziyi Wang, , , | Summary: Structurally distorting low-dimensional pi-conjugated systems can profoundly influence their electronic properties, but controlling such behavior in extended-width systems remains challenging. Here we demonstrate that a one-dimensional conjugated polymer, poly-(difluorenoheptalene-ethynylene) (PDFHE), undergoes a pronounced out-of-plane backbone distortion, equivalent to […]


Continue.. Jahn-Teller-like Distortion in a One-dimensional π-Conjugated Polymer

An Anterior Cingulate Cortex Neuronal Ensemble Controls Contextual Opioid Analgesic Tolerance

Posted by dbos Yale

Kavli Affiliate: Marina Picciotto | Rafael E Perez, Yann S Mineur, Cheryl Chen, Wenliang Zhou, Julian Lee Thompsom, Saagar S Motupally, Angelica Minier-Toribio and Marina R Picciotto | Summary: Despite well-established cellular and molecular adaptations, opioid analgesic tolerance can be rapidly reversed in settings where these drugs are not expected. The specific neuronal populations that […]


Continue.. An Anterior Cingulate Cortex Neuronal Ensemble Controls Contextual Opioid Analgesic Tolerance