Kavli Affiliate: Pietro DeCamilli, Kenneth Miller | Authors: Junhyun Park, Kenneth G. Miller, Pietro De Camilli and Shaul Yogev | Summary: Axonal transport is key to neuronal function. Efficient transport requires specific motor-cargo association in the soma, yet the mechanisms regulating this early step remain poorly understood. We found that EBP-1, the C. elegans ortholog […]
Continue.. End Binding protein 1 promotes specific motor-cargo association in the cell body prior to axonal delivery of Dense Core Vesicles