Kavli Affiliate: Shinichiro Takeda
| First 5 Authors: Goro Yabu, Hiroki Yoneda, Tadashi Orita, Shin’ichiro Takeda, Pietro Caradonna
| Summary:
Tomographic imaging with radionuclides commonly used in nuclear medicine,
such as $^{111}$In (171 and 245 keV) and $^{131}$I (364 keV), is in high demand
for medical applications and small animal imaging. The Si/CdTe Compton camera
with its high angular and high energy resolutions is an especially promising
detector to extend the energy coverage for imaging to the range that covers
gamma-ray emitted from these radionuclides. Here, we take the first steps
towards short-distance imaging by conducting experiments using
three-dimensional phantoms composed of multiple sphere-like solutions of
$^{111}$In and $^{131}$I with a diameter of 2.7 mm, placed at a distance of 41
mm. Using simple back-projection methods, the positions of the sources are
reproduced with a spatial resolution of 11.5 mm and 9.0 mm (FWHM) for
$^{111}$In and $^{131}$I, respectively. We found that a LM-MLEM method gives a
better resolution of 4.0 mm and 2.7 mm (FWHM). We resolve source positions of a
tetrahedron structure with a source-to-source separation of 28 mm. These
findings demonstrate that Compton Cameras have the potential of close-distance
imaging of radioisotopes distributions in the energy range below 400 keV.
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