Kavli Affiliate: John Carlson | Authors: Wanyue Wang, Hany K M Dweck, Gaëlle J.S. Talross, Ali Zaidi, Joshua M Gendron and John R Carlson | Summary: The agricultural pest Drosophila suzukii differs from most other Drosophila species in that it lays eggs in ripe, rather than overripe, fruit. Previously we showed that changes in bitter […]
Kavli Affiliate: Pietro DeCamilli | Authors: Daehun Park, Yumei Wu, Aaron Baublis and Pietro De Camilli | Summary: Ectopic expression in fibroblasts of synapsin 1 and synaptophysin is sufficient to generate condensates of vesicles highly reminiscent of synaptic vesicle (SV) clusters and with liquid-like properties. We show that unlike synaptophysin, other major integral SV membrane […]
Kavli Affiliate: Michael Crair | Authors: David O’Connor, Francesca Mandino, Xilin Shen, Corey Horien, Xinxin Ge, Peter Herman, Michael Crair, Xenophon Papademetris, Evelyn MR Lake and Robert Todd Constable | Summary: To improve bench-to-bedside translation, it is integral that knowledge flow bidirectionally from – animal models to humans, and vice versa. This will be facilitated […]
Kavli Affiliate: Shawn Ferguson | Authors: Jaekwang Jeong, Jongwon Lee, Gabriel Talaia, Wonnam Kim, Junho Song, Kwangmin Yoo, David G. Gonzalez, Diana Athonvarangkul, Jaehun Shin, Pamela Dann, Ann M Haberman, Lark Kyun Kim, Shawn M. Ferguson, Jungmin Choi and John Wysolmerski | Summary: Involution of the mammary gland after lactation is a dramatic example of […]
Kavli Affiliate: Robert Edwards | Authors: Michael J. Roach, Sarah Beecroft, Kathie Mihindukulasuriya, Leran Wang, Lais Farias Oliveira Lima, Elizabeth A. Dinsdale, Robert Edwards and Scott Allyn Handley | Summary: The CRISPR-Cas9 system has enabled researchers to precisely modify/edit the sequence of a genome. A typical editing experiment consists of two steps: (i) editing cultured […]
Kavli Affiliate: Jessica Cardin | Authors: Quentin Perrenoud, Antonio H. de O. Fonseca, Austin Airhart, James Bonanno, Rong Mao and Jessica A Cardin | Summary: Although behaviorally relevant patterns of neocortical activity in specific frequency bands have been broadly characterized, identifying individual underlying network events remains a key challenge in understanding information processing in cortical […]
Kavli Affiliate: Shawn Ferguson | Authors: Oliver Glomb, Grace Swaim, Pablo Munoz LLancao, Christopher Lovejoy, Sabyasachi Sutradhar, Junhyun Park, Youjun Wu, Marc Hammarlund, Jonathon Howard, Shawn M. Ferguson and Shaul Yogev | Summary: A periodic lattice of actin rings and spectrin tetramers scaffolds the axonal membrane. How spectrin is delivered to this structure to scale […]
Kavli Affiliate: Stephen Strittmatter | Authors: Bridget Shafit-Zagardo, Simone Sidoli, James E. Goldman, Juwen C DuBois, John R Corboy, Stephen M. Strittmatter, Hillary Guzik, Sarah Graff and Rashed M Nagra | Summary: During inflammatory, demyelinating diseases such as multiple sclerosis (MS) axonal damage is prevalent early in the disease course. Axonal damage includes swellings, defects […]
Kavli Affiliate: Joerg Bewersdorf | Authors: Andrew E. S. Barentine, Yu Lin, Edward M Courvan, Phylicia Kidd, Miao Liu, Leonhard Balduf, Timy Phan, Felix Rivera-Molina, Michael R. Grace, Zach Marin, Mark Lessard, Juliana Rios-Chen, Siyuan Wang, Karla M Neugebauer, Joerg Bewersdorf and David Baddeley | Summary: Diffraction-unlimited single-molecule techniques like STORM and (F)PALM enable three-dimensional […]
Kavli Affiliate: Marvin Chun | Authors: Omid Kardan, Andrew J Stier, Carlos Cardenas-Inigues, Julia C Pruin, Kathryn E Schertz, Yuting Deng, Taylor Chamberlain, Wesley J Meredith, Xihan Zhang, Jilian E Bowman, Tanvi Lakhtakia, Lucy Tindel, Emily W Avery, Qi Lin, Kwangsun Yoo, Marvin M Chun, Marc G Berman and Monica D Rosenberg | Summary: Sustained […]