Hippocampus as a generative circuit for predictive coding of future sequences

Kavli Affiliate: Terrence Sejnowski | Authors: Yusi Chen, Huanqiu Zhang and Terrence J Sejnowski | Summary: The interaction between hippocampus and cortex is key to memory formation and representation learning. Based on anatomical wiring and transmission delays, we proposed a self-supervised recurrent neural network (PredRAE) with a predictive reconstruction loss to account for the cognitive […]


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Interactive Neurorobotics: Behavioral and Neural Dynamics of Agent Interactions

Kavli Affiliate: Andrea Chiba | Authors: Eric J Leonardis, Leo Breston, Rhiannon Lucero-Moore, Leigh Sena, Raunit Kohli, Luisa Schuster, Lacha Barton-Gluzman, Laleh K Quinn, Janet Wiles and Andrea Chiba | Summary: Interactive neurorobotics is a subfield which characterizes brain responses evoked during interaction with a robot, and their relationship with the behavioral responses. Gathering rich […]


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Immunomodulatory Extracellular Matrix Hydrogel Mitigates Scar Formation in a Model of Tongue Fibrosis.

Kavli Affiliate: Karen Christman | Authors: mma I Zelus, Aaron Panduro, Marianna Alperin, Andrew M Vahabzadeh-Hagh and Karen L Christman | Summary: Background: While head and neck cancer treatment regimens, including surgical resection, irradiation, and chemotherapy, are effective at removing tumors, they lead to muscle atrophy, denervation, and fibrosis, contributing to the pathogenesis of tongue […]


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Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response

Kavli Affiliate: Wesley Thompson | Authors: Meghana Pagadala, Victoria H. Wu, Eva Perez-Guijarro, Hyo Kim, Andrea Castro, James Talwar, Timothy Sears, Cristian Gonzalez-Colin, Steven Cao, Benjamin Schmiedel, Shervin Goudarzi, Divya Kirani, Rany Salem, Gerald Morris, Olivier Harismendy, Sandip Pravin Patel, Jill P. Mesirov, Maurizio Zanetti, Chi-Ping Day, Chun Chieh Fan, Wesley K. Thompson, Glenn Merlino, […]


Continue.. Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response

Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission

Kavli Affiliate: Fred Gage | Authors: Shani Stern, Lei Zhang, Meiyan Wang, Rebecca Wright, Diogo Cordeiro, David Peles, Yuqing Hang, Ana P Mendes, Tithi Baul, Julien Roth, Shashank Coorapati, Marco Boks, Hilleke Hulshoff Pol, Kristen J. Brennand, Janos M Rethelyi, Rene S. Kahn, Maria C. Marchetto and Fred H. Gage | Summary: Schizophrenia affects approximately […]


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BigNeuron: A resource to benchmark and predict best-performing algorithms for automated reconstruction of neuronal morphology

Kavli Affiliate: Ann Shyn Chiang, Kristofer Bouchard | Authors: Linus Manubens-Gil, Zhi Zhou, Hanbo Chen, Arvind Ramanathan, Xiaoxiao Liu, Yufeng Liu, Alessandro Bria, Todd Gillette, Zongcai Ruan, Jian Yang, Miroslav Radojević, Ting Zhao, Li Cheng, Lei Qu, Siqi Liu, Kristofer E. Bouchard, Lin Gu, Weidong Cai, Shuiwang Ji, Badrinath Roysam, Ching-Wei Wang, Hongchuan Yu, Amos […]


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Repeated birth injuries lead to pelvic floor muscle dysfunction and impairment in regeneration

Kavli Affiliate: Karen Christman | Authors: Pamela Duran, Emma Zelus, Saya French, Lindsey Burnett, Karen Christman and Marianna Alperin | Summary: Objectives: Childbirth is a key risk factor for pelvic floor muscle (PFM) injury and dysfunction, and subsequent pelvic floor disorders (PFDs). Multiparity further exacerbates these risks. Using the pre-clinical rat model of simulated birth […]


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High precision magnetoencephalography reveals increased right-inferior frontal gyrus beta power during response conflict

Kavli Affiliate: Adam Aron | Authors: Pria L Daniel, James J Bonaiuto, Sven Bestmann, Adam R Aron and Simon Little | Summary: Flexibility of behavior and the ability to rapidly switch actions is critical for adaptive living in humans. It is well established that the right-inferior frontal gyrus (R-IFG) is recruited during outright action-stopping, relating […]


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Altered basal ganglia output during self-restraint

Kavli Affiliate: Joshua Berke | Authors: Bon-Mi Gu and Joshua D. Berke | Summary: Suppressing actions is essential for flexible behavior. Multiple neural circuits involved in behavioral inhibition converge upon a key basal ganglia output nucleus, the substantia nigra pars reticulata (SNr). To examine how changes in basal ganglia output contribute to self-restraint, we recorded […]


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Flexible utilization of spatial- and motor-based codes for the storage of visuo-spatial information

Kavli Affiliate: John Serences | Authors: Margaret M. Henderson, Rosanne L. Rademaker and John T. Serences | Summary: Working memory provides flexible storage of information in service of upcoming behavioral goals. Some models propose specific fixed loci and mechanisms for the storage of visual information in working memory, such as sustained spiking in parietal and […]


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