Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission

Kavli Affiliate: Fred Gage | Authors: Shani Stern, Lei Zhang, Meiyan Wang, Rebecca Wright, Diogo Cordeiro, David Peles, Yuqing Hang, Ana P Mendes, Tithi Baul, Julien Roth, Shashank Coorapati, Marco Boks, Hilleke Hulshoff Pol, Kristen J. Brennand, Janos M Rethelyi, Rene S. Kahn, Maria C. Marchetto and Fred H. Gage | Summary: Schizophrenia affects approximately […]


Continue.. Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission

BigNeuron: A resource to benchmark and predict best-performing algorithms for automated reconstruction of neuronal morphology

Kavli Affiliate: Ann Shyn Chiang, Kristofer Bouchard | Authors: Linus Manubens-Gil, Zhi Zhou, Hanbo Chen, Arvind Ramanathan, Xiaoxiao Liu, Yufeng Liu, Alessandro Bria, Todd Gillette, Zongcai Ruan, Jian Yang, Miroslav Radojević, Ting Zhao, Li Cheng, Lei Qu, Siqi Liu, Kristofer E. Bouchard, Lin Gu, Weidong Cai, Shuiwang Ji, Badrinath Roysam, Ching-Wei Wang, Hongchuan Yu, Amos […]


Continue.. BigNeuron: A resource to benchmark and predict best-performing algorithms for automated reconstruction of neuronal morphology

Repeated birth injuries lead to pelvic floor muscle dysfunction and impairment in regeneration

Kavli Affiliate: Karen Christman | Authors: Pamela Duran, Emma Zelus, Saya French, Lindsey Burnett, Karen Christman and Marianna Alperin | Summary: Objectives: Childbirth is a key risk factor for pelvic floor muscle (PFM) injury and dysfunction, and subsequent pelvic floor disorders (PFDs). Multiparity further exacerbates these risks. Using the pre-clinical rat model of simulated birth […]


Continue.. Repeated birth injuries lead to pelvic floor muscle dysfunction and impairment in regeneration

High precision magnetoencephalography reveals increased right-inferior frontal gyrus beta power during response conflict

Kavli Affiliate: Adam Aron | Authors: Pria L Daniel, James J Bonaiuto, Sven Bestmann, Adam R Aron and Simon Little | Summary: Flexibility of behavior and the ability to rapidly switch actions is critical for adaptive living in humans. It is well established that the right-inferior frontal gyrus (R-IFG) is recruited during outright action-stopping, relating […]


Continue.. High precision magnetoencephalography reveals increased right-inferior frontal gyrus beta power during response conflict

Altered basal ganglia output during self-restraint

Kavli Affiliate: Joshua Berke | Authors: Bon-Mi Gu and Joshua D. Berke | Summary: Suppressing actions is essential for flexible behavior. Multiple neural circuits involved in behavioral inhibition converge upon a key basal ganglia output nucleus, the substantia nigra pars reticulata (SNr). To examine how changes in basal ganglia output contribute to self-restraint, we recorded […]


Continue.. Altered basal ganglia output during self-restraint

Flexible utilization of spatial- and motor-based codes for the storage of visuo-spatial information

Kavli Affiliate: John Serences | Authors: Margaret M. Henderson, Rosanne L. Rademaker and John T. Serences | Summary: Working memory provides flexible storage of information in service of upcoming behavioral goals. Some models propose specific fixed loci and mechanisms for the storage of visual information in working memory, such as sustained spiking in parietal and […]


Continue.. Flexible utilization of spatial- and motor-based codes for the storage of visuo-spatial information

Dysregulation of neuroproteasomes by ApoE isoforms drives endogenous Tau aggregation

Kavli Affiliate: V. S. Ramachandran | Authors: Victoria Paradise, Malavika Sabu, Joanna Bafia, Nyle A Sharif, Chi Nguyen, Rijuta Dhanraj Mukim, Kalin D Konrad-Vicario, Xiao Wang, Bianca T Corjuc, Jack Fu, Gabriella Maldonado, Jeffrey Ndubisi, Michael Strickland, Helen Figueroa, Douglas L Almeida, Bradley T Hyman, David M Holtzman, Tal Nuriel and Kapil V Ramachandran | […]


Continue.. Dysregulation of neuroproteasomes by ApoE isoforms drives endogenous Tau aggregation

Context-dependent sensory modulation underlies Bayesian vocal sequence perception

Kavli Affiliate: Ali Brivanlou, Eric Siggia | Authors: Anna Yoney, Lu Bai, Ali H. Brivanlou and Eric D Siggia | Summary: Vocal communication in both songbirds and humans relies on categorical perception of smoothly varying acoustic spaces. Vocal perception can be biased by expectation and context, but the mechanisms of this bias are not well […]


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Identification of plasma proteins associated with oesophageal cancer chemotherapeutic treatment outcomes using SWATH-MS

Kavli Affiliate: John Reynolds | Authors: Naici Guo, Giorgos Minas, Silvia A Synowsky, Margaret R Dunne, Hasnain Ahmed, Rhiannon McShane, Anshul Bhardwaj, Noel E Donlon, Cliona Lorton, Jacintha O’Sullivan, John V Reynolds, Peter D Caie, Sally L Shirran, Andy G Lynch, Alan Stewart and Swati Arya | Summary: Oesophageal adenocarcinoma (OAC) is an aggressive cancer […]


Continue.. Identification of plasma proteins associated with oesophageal cancer chemotherapeutic treatment outcomes using SWATH-MS

Active vision during prey-capture in wild marmoset monkeys

Kavli Affiliate: Cory Miller | Authors: Victoria Ngo, Cory Miller, Julia Gorman, Maria Fernanda De La Fuente, Antonio Souto and Nicola Schiel | Summary: Here, we examined prey-capture in wild common marmosets (Callithrix jacchus) to explicate the active role of primate vision for high-precision, goal-directed motor actions in challenging natural environments. We observed distinct marmoset […]


Continue.. Active vision during prey-capture in wild marmoset monkeys