Kavli Affiliate: Kay Tye | Authors: Fergil Mills, Christopher R Lee, James R Howe, Hao Li, Shan Shao, Maria N Keisler, Mackenzie E Lemieux, Felix H Taschbach, Laurel R Keyes, Matilde R Borio, Hannah S Chen, Reesha R. Patel, Alexa L Gross, Jeremy Delahanty, Christian Cazares, Liezl Maree, Romy Wichmann, Talmo D Pereira, Marcus K […]
Kavli Affiliate: John Reynolds | Authors: Zachary W Davis, Nicholas M Dotson, Tom Franken, Lyle Muller and John Reynolds | Summary: Abstract The cortical column is one of the fundamental computational circuits in the brain. In order to understand the role neurons in different layers of this circuit play in cortical function it is necessary […]
Kavli Affiliate: Jill Leutgeb | Authors: Silvia Viana da Silva, Matthias G Haberl, Kshitij Gaur, Rina Patel, Gautam Narayan, Max Ledakis, Maylin L. Fu, Edward H. Koo, Jill K. Leutgeb and Stefan Leutgeb | Summary: Abstract Deficits in spatial navigation are among the early symptoms in Alzheimer’s disease patients, consistent with the hippocampal formation as […]
Kavli Affiliate: Terrence Sejnowski | Authors: Antonio Pinto-Duarte, Katherine Bogue, Terrence J Sejnowski and Shyam Srinivasan | Summary: Abstract The neocortex and paleocortex process sensory information and take part in higher cognitive tasks such as decision-making. The environment of the circuits within these regions is largely controlled by glial cells. Studies have shown that, across […]
Kavli Affiliate: Gabriel Silva | Authors: Vivek K George, Vikash N Morar and Gabriel A Silva | Summary: Abstract Spike-timing dependent plasticity (STDP) is widely accepted as a mechanism through which the brain can learn information from different stimuli. Basing synaptic changes on the timing between presynaptic and postsynaptic spikes enhances contributing edges within a […]
Kavli Affiliate: Jose Suarez Lopez | Authors: Mehdi Bouhaddou, Ann-Kathrin Reuschl, Benjamin J. Polacco, Lucy G. Thorne, Manisha R. Ummadi, Chengjin Ye, Romel Rosales Ramirez, Adrian Pelin, Jyoti Batra, Gwendolyn M. Jang, Jiewei Xu, Jack M. Moen, Alicia L. Richards, Yuan Zhou, Bhavya Harjai, Erica Stevenson, Ajda Rojc, Roberta Ragazzini, Matthew V.X. Whelan, Wilhelm Furnon, […]
Kavli Affiliate: Tatyana Sharpee | Authors: Delany Rodriguez, Lorenzo Fiengo, Martin Alvarez-Kuglen, Haodong Qin, Chen Farhy, Aaron Havas, Rozalyn M Anderson, Peter D Adams, Tatyana O Sharpee and Alexey Terskikh | Summary: ABSTRACT Predictive biomarkers of functional or biological age are key for evaluating interventions aimed at increasing healthspan and / or lifespan in humans. […]
Kavli Affiliate: Terrence Sejnowski | Authors: Nuttida Rungratsameetaweemana, Robert Kim and Terrence Sejnowski | Summary: Abstract Recurrent neural networks (RNNs) based on model neurons that communicate via continuous signals have been widely used to study how cortical neurons perform cognitive tasks. Training such networks to perform tasks that require information maintenance over a brief period […]
Kavli Affiliate: Terrence Sejnowski | Authors: Antonio Pinto-Duarte, Katherine Bogue, Terrence J Sejnowski and Shyam Srinivasan | Summary: Abstract Epigenetic changes are involved in the onset and progression of cancer, and the detection of DNA methylation signatures may foster the improvement of diagnosis and prognosis. While the emergence of innovative technologies has fostered numerous studies […]
Kavli Affiliate: Eran Mukamel | Authors: Matthew G Heffel, Jingtian Zhou, Yi Zhang, Dong-Sung Lee, Kangcheng Hou, Oier Pastor Alonso, Kevin Abuhanna, Anthony D Schmitt, Terence Li, Maximilian Haeussler, Brittney Wick, Martin Jinye Zhang, Fangming Xie, Ryan S Ziffra, Eran A Mukamel, Eleazar Eskin, Bogdan Pasaniuc, Joseph R. Ecker, Jesse Dixon, Tomasz J. Nowakowski, Mercedes […]