Vocal learning-associated convergent evolution in mammalian proteins and regulatory elements

Kavli Affiliate: Eiman Azim | Authors: Morgan E Wirthlin, Tobias A. Schmid, Julie E. Elie, Xiaomeng Zhang, Varvara A. Shvareva, Ashley Rakuljic, Maria B. Ji, Ninad S. Bhat, Irene M. Kaplow, Daniel E. Schäffer, Alyssa J. Lawler, Siddharth Annaldasula, Byungkook Lim, Eiman Azim, Zoonomia Consortium, Wynn K. Meyer, Michael M. Yartsev and Andreas R. Pfenning […]


Continue.. Vocal learning-associated convergent evolution in mammalian proteins and regulatory elements

Upregulated extracellular matrix-related genes and impaired synaptic activity in dopaminergic and hippocampal neurons derived from Parkinson’s disease patients with PINK1 and PARK2 mutations

Kavli Affiliate: Fred Gage | Authors: Utkarsh Tripathi, Idan Rosh, Ran Ben Ezer, Ritu Nayak, Ashwani Choudhary, Jose Djamus, Andreea Manole, Henry Houlden, Fred H. Gage and Shani Stern | Summary: Abstract Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease. Primary symptoms of PD arise with the loss of dopaminergic (DA) neurons in […]


Continue.. Upregulated extracellular matrix-related genes and impaired synaptic activity in dopaminergic and hippocampal neurons derived from Parkinson’s disease patients with PINK1 and PARK2 mutations

Violation of the ultrastructural size principle in the dorsolateral prefrontal cortex underlies working memory impairment in the aged common marmoset (Callithrix jacchus)

Kavli Affiliate: John Reynolds | Authors: Courtney Glavis-Bloom, Casey R Vanderlip, Sammy Weiser Novak, Masaaki Kuwajima, Lyndsey Kirk, Uri Manor, Kristen M Harris and John H Reynolds | Summary: ABSTRACT Working memory relies critically on the dorsolateral prefrontal cortex (dlPFC). Morphology and function of the dlPFC, and corresponding working memory performance, are affected early in […]


Continue.. Violation of the ultrastructural size principle in the dorsolateral prefrontal cortex underlies working memory impairment in the aged common marmoset (Callithrix jacchus)

BDNF and TRiC-inspired Reagents Rescue Cortical Synaptic Deficits in a Mouse Model of Huntington’s Disease

Kavli Affiliate: William Mobley | Authors: Yingli Gu, Alexander Pope, Charlene Smith-Geater, Christopher Carmona, Aaron Johnstone, Linda Shi, Xuqiao Chen, Sarai Santos, Claire C Bacon-Brenes, Thomas Shoff, Korbin M Kleczko, Judith Frydman, Leslie M Thompson, William C Mobley and Chengbiao Wu | Summary: Abstract Huntington’s disease (HD) results from a CAG repeat expansion in the […]


Continue.. BDNF and TRiC-inspired Reagents Rescue Cortical Synaptic Deficits in a Mouse Model of Huntington’s Disease

Copiotrophs dominate rhizosphere microbiomes and growth rate potential is a major factor explaining the rhizosphere effect

Kavli Affiliate: Jose Suarez Lopez | Authors: José Luis López, Nikolaos Pappas, Sanne WM Poppeliers, Juan J. Sanchez-Gil, Arista Fourie-Fouche, Ronnie de Jonge and Bas E. Dutilh | Summary: Abstract The structure and function of the root microbial community is shaped by plant root activity, enriching specific microbial taxa and functions from the surrounding soil […]


Continue.. Copiotrophs dominate rhizosphere microbiomes and growth rate potential is a major factor explaining the rhizosphere effect

Factors governing attachment of Rhizobium leguminosarum to legume roots

Kavli Affiliate: V. S. Ramachandran | Authors: Jack Parsons, Clare Cocker, Alison East, Rachel Wheatley, Vinoy Ramachandran, Farnusch Kaschani, Markus Kaiser and Philip Poole | Summary: Abstract Primary attachment of rhizobia to host legume roots depends on pH and is the first physical interaction during nodulation. Genome-wide insertion sequencing, luminescence-based attachment assays and proteomic analysis […]


Continue.. Factors governing attachment of Rhizobium leguminosarum to legume roots

Subcellular niche segregation of co-obligate symbionts in whiteflies

Kavli Affiliate: Ying Meng | Authors: Akiko FUJIWARA, Xian-Ying Meng, Yoichi Kamagata and Tsutomu TSUCHIDA | Summary: Abstract Many insects contain endosymbiotic bacteria within their bodies. In multiple endosymbiotic systems comprising two or more symbionts, each of the symbionts is generally localized in a different host cell or tissue. Bemisia tabaci (Sweet potato whitefly)possesses a […]


Continue.. Subcellular niche segregation of co-obligate symbionts in whiteflies

Quadratic computations maintain neural specificity to natural stimuli across stages of visual processing

Kavli Affiliate: Tatyana Sharpee | Authors: Ryan J. Rowekamp and Tatyana Sharpee | Summary: Abstract Despite recent successes in machine vision, artificial recognition systems continue to be less robust than biological systems. The brittleness of artificial recognition system has been attributed to the linearity of the core operation that matches inputs to target patterns at […]


Continue.. Quadratic computations maintain neural specificity to natural stimuli across stages of visual processing

Divergent impacts of C9orf72 repeat expansion on neurons and glia in ALS and FTD

Kavli Affiliate: Eran Mukamel | Authors: Junhao Li, Manoj K Jaiswal, Jo-Fan Chien, Alexey Kozlenkov, Ping Zhou, Mahammad Gardashli, Luc J Pregent, Erica Engelberg-Cook, Dennis W Dickson, Veronique V Belzil, Eran A Mukamel and Stella Dracheva | Summary: Abstract Neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), are strongly influenced by […]


Continue.. Divergent impacts of C9orf72 repeat expansion on neurons and glia in ALS and FTD

An open-access EEG dataset for speech decoding: Exploring the role of articulation and coarticulation

Kavli Affiliate: Terrence Sejnowski | Authors: João Pedro Carvalho Moriera, Vinícius Rezende Carvalho, Eduardo Mazoni Andrade Marçal Mendes, Aria Fallah, Terrence J. Sejnowski, Claudia Lainscsek and Lindy B Comstock | Summary: Abstract Electroencephalography (EEG) holds promise for brain-computer interface (BCI) devices as a non-invasive measure of neural activity. With increased attention to EEG-based BCI systems, […]


Continue.. An open-access EEG dataset for speech decoding: Exploring the role of articulation and coarticulation