Kavli Affiliate: Timothy Brown | Authors: Boaz Mohar, Jonathan B. Grimm, Ronak Patel, Timothy A. Brown, Paul Tillberg, Luke D. Lavis, Nelson Spruston and Karel Svoboda | Summary: Cellular functions are regulated by synthesizing and degrading proteins on time scales ranging from minutes to weeks. Protein turnover varies across proteins, cellular compartments, cell types, and […]
Kavli Affiliate: Terrence Sejnowski | Authors: Nuttida Rungratsameetaweemana, Robert Kim, Thiparat Chotibut and Terrence Sejnowski | Summary: Recurrent neural networks (RNNs) based on model neurons that communicate via continuous signals have been widely used to study how cortical neurons perform cognitive tasks. Training such networks to perform tasks that require information maintenance over a brief […]
Kavli Affiliate: Cory Miller | Authors: Timothy Tyree, Michael Metke and Cory Miller | Summary: Faces and voices are the dominant social signals used to recognize individuals amongst human and nonhuman primates (1–4). Yet it is not known how these critical signals are integrated into a cross-modal representation of individual identity in the primate brain. […]
Kavli Affiliate: Mark Ellisman | Authors: Yaeram Jeong, chung-ha Davis, Aaron Muscarella, Viraj Deshpande, Keun-Young Kim, Mark Ellisman and Nicholas Marsh-Armstrong | Summary: We previously described a process referred to as transmitophagy where mitochondria shed by retinal ganglion cell (RGC) axons are transferred to and degraded by surrounding astrocytes in the optic nerve head of […]
Kavli Affiliate: Mark Ellisman | Authors: George A. Spirou, Matthew Kersting, Sean Carr, Bayan Razzaq, Carolyna Y. Alves-Pinto, Mariah Dawson, Mark H. Ellisman and Paul B. Manis | Summary: Globular bushy cells (GBCs) of the cochlear nucleus play central roles in the temporal processing of sound. Despite investigation over many decades, fundamental questions remain about […]
Kavli Affiliate: John Reynolds | Authors: Courtney Glavis-Bloom, Casey R Vanderlip, Payton A Asch and John H Reynolds | Summary: Age-related cognitive impairment is not expressed uniformly across cognitive domains. Cognitive functions that rely on brain areas that undergo substantial neuroanatomical changes with age often show age-related impairment, while those that rely on brain areas […]
Kavli Affiliate: Kay Tye | Authors: Eyal Y. Kimchi, Anthony Burgos-Robles, Gillian A Matthews, Tatenda Chakoma, Makenzie Patarino, Javier C Weddington, Cody A Siciliano, Wannan Yang, Shaun Foutch, Renee Simons, Ming-fai Fong, miao jing, Yulong Li, Daniel B Polley and Kay M. Tye | Summary: Basal forebrain cholinergic neurons modulate how organisms process and respond […]
Kavli Affiliate: Sreekanth Chalasani | Authors: Amy Pribadi, Michael A Rieger, Kaila Rosales, Kirthi C Reddy and Sreekanth H Chalasani | Summary: Prey respond to predators by altering their behavior to optimize their own fitness and survival. Specifically, prey are known to avoid predator-occupied territories to reduce their risk of harm or injury to themselves […]
Kavli Affiliate: Douglas Nitz | Authors: Yanjun Sun, Douglas A Nitz, Xiangmin Xu and Lisa M Giocomo | Summary: Corners are a cardinal feature of many of the complex environmental geometries found in the natural world but the neural substrates that could underlie the perception of corners remain elusive. Here we show that the dorsal […]
Kavli Affiliate: Marcelo Mattar | Authors: Li Ji-An, Marcus K Benna and Marcelo G Mattar | Summary: Normative frameworks such as Bayesian inference and reward-based learning are useful tools for explaining the fundamental principles of adaptive behavior. However, their ability to describe realistic animal behavior is limited by the often small number of parameters that […]