Insulin/IGF Signaling Regulates Presynaptic Glutamate Release in Aversive Olfactory Learning

Kavli Affiliate: Cornelia Bargmann | Authors: Du Cheng, James Lee, Maximillian Brown, Margaret S. Ebert, Masahiro Tomioka, Yuichi Iino and Cornelia I Bargmann | Summary: Information flow through neural circuits is continuously modified by context-dependent learning. In the nematode Caenorhabditis elegans, pairing specific odors with food deprivation results in aversion to the odor. Here we […]


Continue.. Insulin/IGF Signaling Regulates Presynaptic Glutamate Release in Aversive Olfactory Learning

Transcriptional and mutational signatures of the aging germline

Kavli Affiliate: Li Zhao | Authors: Evan Witt, Christopher B Langer, Nicolas Svetec and Li Zhao | Summary: Abstract Aging is a complex biological process that is accompanied by changes in gene expression and mutational load. In many species, including humans, older fathers pass on more paternally-derived de novo mutations; however, the cellular basis and […]


Continue.. Transcriptional and mutational signatures of the aging germline