Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq

Kavli Affiliate: Jean Laurent Casanova | Authors: Sara E Vazquez, Sabrina A Mann, Aaron Bodansky, Andrew F Kung, Zoe Quandt, Elise M N Ferré, Nils Landegren, Daniel Eriksson, Paul Bastard, Shen-Ying Zhang, Jamin Liu, Anthea Mitchell, Caleigh Mandel-Brehm, Brenda Miao, Gavin Sowa, Kelsey Zorn, Alice Y Chan, Chisato Shimizu, Adriana Tremoulet, Kara Lynch, Michael R […]


Continue.. Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq

Global Spatial Transcriptome of Macaque Brain at Single-Cell Resolution

Kavli Affiliate: Li Zhao | Authors: Ao Chen, Yidi Sun, Ying Lei, Chao Li, Sha Liao, Zhifeng Liang, Feng Lin, Nini Yuan, Mei Li, Kexin Wang, Meisong Yang, Shuzhen Zhang, Zhenkun Zhuang, Juan Meng, Qiong Song, Yong Zhang, Yuanfang Xu, Luman Cui, Lei Han, Hao Yang, Xing Sun, Tianyi Fei, Bichao Chen, Wenjiao Li, Baoqian […]


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Automated assembly of high-quality diploid human reference genomes

Kavli Affiliate: Erich Jarvis | Authors: Erich D. Jarvis, Giulio Formenti, Arang Rhie, Andrea Guarracino, Chentao Yang, Jonathan Wood, Alan Tracey, Francoise Thibaud-Nissen, Mitchell R Vollger, David Porubsky, Haoyu Cheng, Mobin Asri, Glennis A Logsdon, Paolo Carnevali, Mark Chaisson, Chen-Shan Chin, Sarah Cody, Joanna Collins, Peter Ebert, Merly Escalona, Olivier Fedrigo, Robert S Fulton, Lucinda […]


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Rapidly evolving genes underlie Aedes aegypti mosquito reproductive resilience during drought

Kavli Affiliate: Li Zhao, Margaret Herre | Authors: Krithika Venkataraman, Nadav Shai, Priyanka Lakhiani, Sarah Zylka, Jieqing Zhao, Margaret Herre, Joshua Zeng, Lauren A Neal, Henrik Molina, Li Zhao and Leslie B Vosshall | Summary: Female Aedes aegypti mosquitoes impose a severe global public health burden as vectors of multiple viral pathogens. Under optimal environmental […]


Continue.. Rapidly evolving genes underlie Aedes aegypti mosquito reproductive resilience during drought

Insulin/IGF Signaling Regulates Presynaptic Glutamate Release in Aversive Olfactory Learning

Kavli Affiliate: Cornelia Bargmann | Authors: Du Cheng, James Lee, Maximillian Brown, Margaret S. Ebert, Masahiro Tomioka, Yuichi Iino and Cornelia I Bargmann | Summary: Information flow through neural circuits is continuously modified by context-dependent learning. In the nematode Caenorhabditis elegans, pairing specific odors with food deprivation results in aversion to the odor. Here we […]


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Transcriptional and mutational signatures of the aging germline

Kavli Affiliate: Li Zhao | Authors: Evan Witt, Christopher B Langer, Nicolas Svetec and Li Zhao | Summary: Abstract Aging is a complex biological process that is accompanied by changes in gene expression and mutational load. In many species, including humans, older fathers pass on more paternally-derived de novo mutations; however, the cellular basis and […]


Continue.. Transcriptional and mutational signatures of the aging germline