Transcriptional and mutational signatures of the aging germline

Kavli Affiliate: Li Zhao | Authors: Evan Witt, Christopher B Langer, Nicolas Svetec and Li Zhao | Summary: Abstract Aging is a complex biological process that is accompanied by changes in gene expression and mutational load. In many species, including humans, older fathers pass on more paternally-derived de novo mutations; however, the cellular basis and […]


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