Parallel systems for social and spatial reasoning within the cortical apex

Kavli Affiliate: Winrich Freiwald | Authors: Ben Deen and Winrich A Freiwald | Summary: What is the cognitive and neural architecture for high-level reasoning? We hypothesize that systems for understanding people and places remain separate throughout the brain, but share a parallel organization. We test this hypothesis using deep neuroimaging of individual human brains on […]


Continue.. Parallel systems for social and spatial reasoning within the cortical apex

Genome-wide detection of human variants that disrupt intronic branchpoints

Kavli Affiliate: Jean Laurent Casanova | Authors: Peng Zhang, Quentin Philippot, Weicheng Ren, Wei-Te Lei, Juan Li, Peter D. Stenson, Pere Soler Palacín, Roger Colobran, Bertrand Boisson, Shen-Ying Zhang, Anne Puel, Qiang Pan-Hammarström, Qian Zhang, David N. Cooper, Laurent Abel and Jean-Laurent Casanova | Summary: Pre-mRNA splicing is initiated with the recognition of a single-nucleotide […]


Continue.. Genome-wide detection of human variants that disrupt intronic branchpoints

Peptidergic signaling controls the dynamics of sickness behavior in Caenorhabditis elegans

Kavli Affiliate: Cori Bargmann | Authors: Javier Marquina-Solis, Elke Vandewyver, Josh Hawk, Daniel Colon-Ramos, Isabel Beets and Cori Bargmann | Summary: Pathogenic infection elicits sickness behaviors that promote recovery and survival of the host. For example, following infection with the pathogenic bacterium Pseudomonas aeruginosa PA14, the nematode Caenorhabditis elegans modifies its sensory preferences to avoid […]


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Mechanisms Underlying WNT-mediated Priming of Human Embryonic Stem Cells

Kavli Affiliate: Ali Brivanlou, Eric Siggia | Authors: Anna Yoney, Lu Bai, Ali H. Brivanlou and Eric D Siggia | Summary: Embryogenesis is guided by a limited set of signaling pathways dynamically expressed in different places. How a context dependent signaling response is generated has been a central question of developmental biology, which can now […]


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Systematic identification of unannotated ORFs in Drosophila reveals evolutionary heterogeneity

Kavli Affiliate: Li Zhao | Authors: Eric B Zheng and Li Zhao | Summary: De novo gene origination, where a previously non-genic genomic sequence becomes genic through evolution, has been increasingly recognized as an important source of evolutionary novelty across diverse taxa. Many de novo genes have been proposed to be protein-coding, and in several […]


Continue.. Systematic identification of unannotated ORFs in Drosophila reveals evolutionary heterogeneity

Impact of prior infection on SARS-CoV-2 antibody responses in vaccinated long-term care facility staff

Kavli Affiliate: Michael Young | Authors: Emily N Gallichotte, Mary Nehring, Sophia Stromberg, Michael C Young, Ashley Snell, Joshua B Daniels, Kristy L. Pabilonia, Sue Vandewoude, Nicole Ehrhart and Gregory D Ebel | Summary: SARS-CoV-2 emerged in 2019 and has resulted in millions of deaths worldwide. Certain populations are at higher risk for infection, especially […]


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Protein evidence of unannotated ORFs in Drosophila reveals unappreciated diversity in the evolution of young proteins

Kavli Affiliate: Li Zhao | Authors: Eric B Zheng and Li Zhao | Summary: Abstract De novo gene origination, where a previously non-genic genomic sequence becomes genic through evolution, has been increasingly recognized as an important source of evolutionary novelty across diverse taxa. Many de novo genes have been proposed to be protein-coding, and in […]


Continue.. Protein evidence of unannotated ORFs in Drosophila reveals unappreciated diversity in the evolution of young proteins

Biological responses to terahertz radiation with different power density in primary hippocampal neurons

Kavli Affiliate: Li Zhao | Authors: Li Zhao, Ruhan Yi, Sun Liu, Yunliang Chi, Shengzhi Tan, Ji Dong, Hui Wang, Jing Zhang, Haoyu Wang, Xinping Xu, Binwei Yao, Bo Wang and Ruiyun Peng | Summary: Background Terahertz (THz) radiation is a valuable imaging and sensing tool which is widely used in industry and medicine. However, […]


Continue.. Biological responses to terahertz radiation with different power density in primary hippocampal neurons

Pangenomics provides insights into the role of synanthropy in barn swallow evolution

Kavli Affiliate: Erich Jarvis | Authors: Simona Secomandi, Guido Roberto Gallo, Marcella Sozzoni, Alessio Iannucci, Elena Galati, Linelle Abueg, Jennifer Balacco, Manuela Caprioli, William Chow, Claudio Ciofi, Joanna Collins, Olivier Fedrigo, Luca Ferretti, Arkarachai Fungtammasan, Bettina Haase, Kerstin Howe, Woori Kwak, Gianluca Lombardo, Patrick Masterson, Graziella Messina, Anders Pape Møller, Jacquelyn Mountcastle, Timothy A. Mousseau, […]


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Gfastats: conversion, evaluation and manipulation of genome sequences using assembly graphs

Kavli Affiliate: Erich Jarvis | Authors: Giulio Formenti, Linelle Abueg, Angelo Brajuka, Nadolina Brajuka, Cristo Gallardo, Alice Giani, Olivier Fedrigo and Erich D. Jarvis | Summary: Motivation With the current pace at which reference genomes are being produced, the availability of tools that can reliably and efficiently generate genome assembly summary statistics has become critical. […]


Continue.. Gfastats: conversion, evaluation and manipulation of genome sequences using assembly graphs