Mechanisms Underlying WNT-mediated Priming of Human Embryonic Stem Cells

Kavli Affiliate: Ali Brivanlou, Eric Siggia | Authors: Anna Yoney, Lu Bai, Ali H. Brivanlou and Eric D Siggia | Summary: Embryogenesis is guided by a limited set of signaling pathways dynamically expressed in different places. How a context dependent signaling response is generated has been a central question of developmental biology, which can now […]


Continue.. Mechanisms Underlying WNT-mediated Priming of Human Embryonic Stem Cells

Systematic identification of unannotated ORFs in Drosophila reveals evolutionary heterogeneity

Kavli Affiliate: Li Zhao | Authors: Eric B Zheng and Li Zhao | Summary: De novo gene origination, where a previously non-genic genomic sequence becomes genic through evolution, has been increasingly recognized as an important source of evolutionary novelty across diverse taxa. Many de novo genes have been proposed to be protein-coding, and in several […]


Continue.. Systematic identification of unannotated ORFs in Drosophila reveals evolutionary heterogeneity

Impact of prior infection on SARS-CoV-2 antibody responses in vaccinated long-term care facility staff

Kavli Affiliate: Michael Young | Authors: Emily N Gallichotte, Mary Nehring, Sophia Stromberg, Michael C Young, Ashley Snell, Joshua B Daniels, Kristy L. Pabilonia, Sue Vandewoude, Nicole Ehrhart and Gregory D Ebel | Summary: SARS-CoV-2 emerged in 2019 and has resulted in millions of deaths worldwide. Certain populations are at higher risk for infection, especially […]


Continue.. Impact of prior infection on SARS-CoV-2 antibody responses in vaccinated long-term care facility staff

Protein evidence of unannotated ORFs in Drosophila reveals unappreciated diversity in the evolution of young proteins

Kavli Affiliate: Li Zhao | Authors: Eric B Zheng and Li Zhao | Summary: Abstract De novo gene origination, where a previously non-genic genomic sequence becomes genic through evolution, has been increasingly recognized as an important source of evolutionary novelty across diverse taxa. Many de novo genes have been proposed to be protein-coding, and in […]


Continue.. Protein evidence of unannotated ORFs in Drosophila reveals unappreciated diversity in the evolution of young proteins

Biological responses to terahertz radiation with different power density in primary hippocampal neurons

Kavli Affiliate: Li Zhao | Authors: Li Zhao, Ruhan Yi, Sun Liu, Yunliang Chi, Shengzhi Tan, Ji Dong, Hui Wang, Jing Zhang, Haoyu Wang, Xinping Xu, Binwei Yao, Bo Wang and Ruiyun Peng | Summary: Background Terahertz (THz) radiation is a valuable imaging and sensing tool which is widely used in industry and medicine. However, […]


Continue.. Biological responses to terahertz radiation with different power density in primary hippocampal neurons

Pangenomics provides insights into the role of synanthropy in barn swallow evolution

Kavli Affiliate: Erich Jarvis | Authors: Simona Secomandi, Guido Roberto Gallo, Marcella Sozzoni, Alessio Iannucci, Elena Galati, Linelle Abueg, Jennifer Balacco, Manuela Caprioli, William Chow, Claudio Ciofi, Joanna Collins, Olivier Fedrigo, Luca Ferretti, Arkarachai Fungtammasan, Bettina Haase, Kerstin Howe, Woori Kwak, Gianluca Lombardo, Patrick Masterson, Graziella Messina, Anders Pape Møller, Jacquelyn Mountcastle, Timothy A. Mousseau, […]


Continue.. Pangenomics provides insights into the role of synanthropy in barn swallow evolution

Gfastats: conversion, evaluation and manipulation of genome sequences using assembly graphs

Kavli Affiliate: Erich Jarvis | Authors: Giulio Formenti, Linelle Abueg, Angelo Brajuka, Nadolina Brajuka, Cristo Gallardo, Alice Giani, Olivier Fedrigo and Erich D. Jarvis | Summary: Motivation With the current pace at which reference genomes are being produced, the availability of tools that can reliably and efficiently generate genome assembly summary statistics has become critical. […]


Continue.. Gfastats: conversion, evaluation and manipulation of genome sequences using assembly graphs

Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq

Kavli Affiliate: Jean Laurent Casanova | Authors: Sara E Vazquez, Sabrina A Mann, Aaron Bodansky, Andrew F Kung, Zoe Quandt, Elise M N Ferré, Nils Landegren, Daniel Eriksson, Paul Bastard, Shen-Ying Zhang, Jamin Liu, Anthea Mitchell, Caleigh Mandel-Brehm, Brenda Miao, Gavin Sowa, Kelsey Zorn, Alice Y Chan, Chisato Shimizu, Adriana Tremoulet, Kara Lynch, Michael R […]


Continue.. Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq

Global Spatial Transcriptome of Macaque Brain at Single-Cell Resolution

Kavli Affiliate: Li Zhao | Authors: Ao Chen, Yidi Sun, Ying Lei, Chao Li, Sha Liao, Zhifeng Liang, Feng Lin, Nini Yuan, Mei Li, Kexin Wang, Meisong Yang, Shuzhen Zhang, Zhenkun Zhuang, Juan Meng, Qiong Song, Yong Zhang, Yuanfang Xu, Luman Cui, Lei Han, Hao Yang, Xing Sun, Tianyi Fei, Bichao Chen, Wenjiao Li, Baoqian […]


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Automated assembly of high-quality diploid human reference genomes

Kavli Affiliate: Erich Jarvis | Authors: Erich D. Jarvis, Giulio Formenti, Arang Rhie, Andrea Guarracino, Chentao Yang, Jonathan Wood, Alan Tracey, Francoise Thibaud-Nissen, Mitchell R Vollger, David Porubsky, Haoyu Cheng, Mobin Asri, Glennis A Logsdon, Paolo Carnevali, Mark Chaisson, Chen-Shan Chin, Sarah Cody, Joanna Collins, Peter Ebert, Merly Escalona, Olivier Fedrigo, Robert S Fulton, Lucinda […]


Continue.. Automated assembly of high-quality diploid human reference genomes