Kavli Affiliate: Gaby Maimon | Authors: Peter Mussells Pires, L F Abbott and Gaby Maimon | Summary: Abstract Neuronal signals relevant for spatial navigation have been described in many species[1-12], however, a circuit-level understanding of how such signals interact to guide behaviour is lacking. Here we characterize a neuronal circuit in the Drosophila central complex […]
Kavli Affiliate: Charles Rice | Authors: Rachel Yamin, Kevin S Kao, Margaret R MacDonald, Tineke Cantaert, Charles M Rice, Jeffrey V Ravetch and Stylianos Bournazos | Summary: Abstract Although dengue virus (DENV) infection typically causes asymptomatic disease, DENV-infected patients can experience severe complications. A risk factor for symptomatic disease is pre-existing anti-DENV IgG antibodies. Cellular […]
Kavli Affiliate: Daniel S. Mucida | Authors: Maria Cecilia C. Canesso, Tiago Bruno Castro, Sandra Nakandakari-Higa, Ainsley Lockhart, Daria Esterhazy, Bernardo Sgarbi Reis, Gabriel D Victora and Daniel Mucida | Summary: Abstract The intestinal immune system must concomitantly tolerate food and commensals and protect against pathogens. Dendritic cells (DCs) orchestrate these immune responses by presenting […]
Kavli Affiliate: Erich Jarvis | Authors: Joseph G Guhlin, Marissa F. Le Lec, Jana Wold, Emily Koot, David Winter, Patrick Biggs, Stephanie J Galla, Lara Urban, Yasmin Foster, Murray P Cox, Andrew Digby, Lydia Uddstrom, Daryl Eason, Deidre Vercoe, Tāne Davis, Kākāpō Recovery Team, Jason T Howard, Erich J Jarvis, Fiona E Robertson, Bruce C […]
Kavli Affiliate: Daniel S. Mucida, Elaine Fuchs | Authors: Siqi Liu, Yun Ha Hur, Xin Cai, Qian Cong, Yihao Yang, Chiwei Xu, Angelina M Bilate, Kevin Andrew Uy Gonzales, Christopher J. Cowley, Brian Hurwitz, Ji-Dung Luo, Tiffany Tseng, Shiri Gur-Cohen, Megan Sribour, Tatiana Omelchenko, John Levorse, H Amalia Pasolli, Criag B Thompson, Daniel Mucida and […]
Kavli Affiliate: Li Zhao | Authors: Bo Tian, Yan Bian, De-Jian Bian, Ye Gao, Xun Zhang, Si-Wei Zhou, Yan-Hui Zhang, Ya-Nan Pang, Zhao-Shen Li and Luo-Wei Wang | Summary: ABSTRACT Background As a processing method of RNA precursors, alternative splicing plays a critical role in normal cell physiological activities. Aberrant alternative splicing events are associated […]
Kavli Affiliate: Michael Young | Authors: Morteza Zabihi, Daniel B. Rubin, Sophie E. Ack, Emily J. Gilmore, Valdery Moura Junior, Sahar F. Zafar, Quanzheng Li, Michael J. Young, Brian L. Edlow, Yelena G. Bodien and Eric S. Rosenthal | Summary: Abstract Accurately predicting emergence from disorders of consciousness (DoC) after acute brain injury can profoundly […]
Kavli Affiliate: Daniel S. Mucida | Authors: Leah A Gates, Bernardo Sgarbi Reis, Peder J Lund, Matthew R Paul, Marylene Leboeuf, Zara Nadeem, Thomas S Carroll, Benjamin Garcia, Daniel Mucida and C. David Allis | Summary: SUMMARY Posttranslational modifications (PTMs) on histone proteins are a key source of regulation on chromatin through impacting genome organization […]
Kavli Affiliate: Jeffrey Friedman | Authors: Anoj Ilanges, Mengyu Xia, Junmei Lu, Lei Chen, Rani Shiao, Changchun Wang, Ru Feng, Zheyu Jin, Han Yi, Qingqing Qi, Jixi Li, Marc Schneeberger, Boxun Lu, Jeffrey M. Friedman and Xiaofei Yu | Summary: Summary Psychological stress and its sequelae are a major public health problem. While the immune […]
Kavli Affiliate: Timothy A. Ryan | Authors: Daniel Charles Cook and Timothy Aidan Ryan | Summary: Abstract Control of neurotransmission efficacy is central to theories of how the brain computes and stores information. Neuromodulators are critical in this problem as they locally influence synaptic strength and can operate on a wide range of time scales. […]