Kavli Affiliate: Seth Blackshaw | Authors: Ying Liu, Clayton Santiago, Akin Sogunro, Gregory K. Konar, Ming-Wen Hu, Minda M. McNally, Yuchen Lu, Zhuolin Li, Dzhalal Agakishiev, Sarah Hadyniak, Katarzyna Hussey, Tyler J. Creamer, Linda D. Orzolek, Derek Teng, Jiang Qian, Zheng Jiang, Robert J. Johnston, Jr., Seth Blackshaw and Mandeep S. Singh | Summary: Human […]
Kavli Affiliate: Peter Searson | Authors: Raleigh M. Linville, Matthew B. Sklar, Gabrielle N. Grifno, Renee F. Nerenberg, Justin Zhou, Robert Ye, Jackson G. DeStefano, Zhaobin Guo, Ria Jha, John J. Jamieson, Nan Zhao and Peter C. Searson | Summary: The blood-brain barrier (BBB) plays a pivotal role in brain health and disease. In the […]
Kavli Affiliate: Michela Gallagher | Authors: Dong-Hee Kim, In-Beom Jin, Nam-Heon Kim, Yong-Jae Jeon, Bo-Ryoung Choi, Michela Gallagher and Jung-Soo Han | Summary: The lateral habenula (LHb) has been implicated in conditioned inhibition. Here, the modulating effects of LHb activity on the association of a conditioned stimulus (CS) with the nonoccurrence of an unconditioned stimulus […]
Kavli Affiliate: David Linden | Authors: J. Kopal, K. Kumar, K. Saltoun, C. Modenato, C. A. Moreau, S. Martin-Brevet, G. Huguet, M. Jean-Louis, C.O. Martin, Z. Saci, N. Younis, P. Tamer, E. Douard, A. M. Maillard, B. Rodriguez-Herreros, A. Pain, S. Richetin, 16p11.2 European Consortium, Simons Searchlight Consortium, L. Kushan, A. I. Silva, M. B. […]
Kavli Affiliate: Michael Miller, Menno Witter | Authors: Kaitlin Stouffer, Menno Witter, Daniel Tward and Michael Miller | Summary: Reconstructing dense 3D anatomical coordinates from 2D projective measurements has become a central problem in both mouse and human digital pathology. We describe a new family of diffeomorphic mapping technologies called Projective LDDMM which generate diffeomorphic […]
Kavli Affiliate: Loyal Goff | Authors: Elizabeth Vincent, Sumantra Chatterjee, Gabrielle H Cannon, Dallas Auer, Holly Ross, Aravinda Chakravarti and Loyal A Goff | Summary: The receptor tyrosine kinase gene RET plays a critical role in the fate specification of enteric neural crest-derived cells (ENCDCs) during enteric nervous system (ENS) development. Pathogenic RET loss of […]
Kavli Affiliate: Paul Greengard | Authors: Ana Milosevic, Lucian Medrihan, Margarete Knudsens, Tatiana Ferraro, Pedro Del Cioppo Vasques, Yevgeniy Romin, Sho Fujisawa and Paul Greengard | Summary: The cholinergic interneurons (ChATs) of the nucleus accumbens (NAc) have a critical role in the activity of this region, specifically in the context of major depressive disorder. To […]
Kavli Affiliate: Brian Caffo | Authors: Qi Huang, Bohao Tang, July Carolina Romero, Yuqian Yang, Saifeldeen Khalil Elsayed, Gayatri Pahapale, Tien-Jung Lee, Itzy Erin Morales Pantoja, Fang Han, Cynthia Berlinicke, Terry Xiang, Mallory Solazzo, Thomas Hartung, Zhao Qin, Brian Caffo, Lena Smirnova and David H Gracias | Summary: Brain organoids are important models for mimicking […]
Kavli Affiliate: Daeyeol Lee | Authors: Maxwell Shinn, Amber Hu, Laurel Turner, Stephanie Noble, Katrin H Preller, Jie Lisa Ji, Flora Moujaes, Sophie Achard, Dustin Scheinost, R Todd Constable, John Krystal, Franz X Vollenweider, Daeyeol Lee, Alan Anticevic, Edward T Bullmore and John D Murray | Summary: High-throughput experimental methods in neuroscience have led to […]
Kavli Affiliate: Seth Blackshaw | Authors: Nguyet Le, Haley Appel, Nicole Pannullo, Thanh Hoang and Seth Blackshaw | Summary: Direct reprogramming of retinal Müller glia is a promising avenue for replacing photoreceptors and retinal ganglion cells lost to retinal dystrophies. However, questions have recently been raised about the accuracy of studies claiming efficient glia-to-neuron reprogramming […]