Kavli Affiliate: David A. Tirrell | Summary:Biological cells sense and respond to mechanical forces, but how such a mechanosensing proccess takes place in a nonlinear inhomogeneous fibrous matrix remains unknown. We show that cells in a fibrous matrix induce deformation fields that propagate over a longer range than predicted by linear elasticity. Synthetic, linear elastic […]
Continue.. Microbuckling of Fibrin Provides a Mechanism for Cell Mechanosensing