Social isolation recruits amygdala-medial prefrontal cortex projections to escalate alcohol drinking in male mice

Posted by dbos UCSD / Salk

  Kavli Affiliate: Kay Tye | Authors: Reesha Patel, Kelly Kim, Makenzie Patarino, Rachelle Pamintuan, Felix Taschbach, Hao Li, Bitna Joo, Anna Pallé, Xianru Yu, Christopher R Lee, Aniek van Hoek, Jesse White, Rogelio Castro, Christian Cazares, Raymundo Miranda, Caroline Jia, Jeremy Delahanty, Kanha Batra, Laurel Keyes, Avraham Libster, Romy W. Wichmann, Talmo Pereira, Marcus […]


Continue.. Social isolation recruits amygdala-medial prefrontal cortex projections to escalate alcohol drinking in male mice

TLR4 signaling drives tissue inflammation, Claudin-5 internalization, and vascular barrier breakdown in a mouse model of neonatal meningitis

Posted by dbos Hopkins

Kavli Affiliate: Jeremy Nathans | Authors: Philip V Seegren, Amir Rattner, Philip M Smallwood and Jeremy Nathans | Summary: Neonatal bacterial meningitis is a leading cause of infant morbidity and mortality, yet the molecular and cellular basis of the leptomeningeal response to infection remains poorly defined. Here, we study a mouse model of neonatal E. […]


Continue.. TLR4 signaling drives tissue inflammation, Claudin-5 internalization, and vascular barrier breakdown in a mouse model of neonatal meningitis

Investigating the Observational Progenitor Mass Gap in the White Dwarf Initial-Final Mass Relation. I. Cluster Census and Characterization of the First White Dwarfs in the Gap

Posted by klaurent Chicago

Kavli Affiliate: David W. Miller | Summary:In recent years, Gaia has been the primary driver of the expansion of the white dwarf (WD) initial-final mass relation (IFMR) in open clusters. The increased sample size has highlighted a pronounced observational gap at progenitor masses of $simeq2$–$2.7,M_odot$, with no spectroscopically confirmed cluster-member WDs in this range. Analysis […]


Continue.. Investigating the Observational Progenitor Mass Gap in the White Dwarf Initial-Final Mass Relation. I. Cluster Census and Characterization of the First White Dwarfs in the Gap

Vigorous turbulence driven by quasar-mode feedback in a cluster core

Posted by klaurent Peking

Kavli Affiliate: Claudio Ricci | Summary:Quasars are among the most luminous objects. They are powered by accretion onto supermassive black holes. They are thought to impact cosmological evolution primarily through energetic winds, known as quasar-mode feedback, yet the efficiency and spatial extent of this process remain poorly constrained. Here we present X-Ray Imaging and Spectroscopy […]


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Measuring Cosmic Neutrino Masses Independently of Dark Energy

Posted by klaurent Cambridge

Kavli Affiliate: Blake Sherwin | Summary:Neutrino oscillations establish that neutrinos are massive, providing the only laboratory detection of physics beyond the Standard Model. Direct kinematic experiments bound the electron-neutrino mass to $m_ν_e < 0.45$ eV (KATRIN, 90% CL), implying $sum m_νlesssim 1.3$ eV. Conversely, cosmology within $Λ$CDM is highly constraining: Planck CMB, CMB lensing, and […]


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Probing an Intermediate-Mass Black Hole Companion of Sagittarius A* with Pulsar Timing

Posted by klaurent Peking

Kavli Affiliate: Lijing Shao | Summary:An intermediate-mass black hole (IMBH) hidden in our Galactic Center (GC) may explain the puzzling observations of the stellar distribution around Sagittarius A* (Sgr A*), the supermassive black hole (SMBH) in the GC. Future observations with the next-generation radio telescopes, such as the SKA, are promising to discover pulsars orbiting […]


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JWST/NIRCam Imaging of Young Stellar Objects. IV. Detailed Imaging of the Protoplanetary Disk around TW Hya

Posted by klaurent Peking

Kavli Affiliate: Ruobing Dong | Summary:As the nearest protoplanetary disk to Earth ($d = 60.14$ pc), TW Hya is one of the most studied protoplanetary disks and a critical benchmark for testing planet formation theories. We present high-contrast coronagraphic imaging of the TW Hya disk from JWST/NIRCam across four filters (F187N, F200W, F356W, and F444W). […]


Continue.. JWST/NIRCam Imaging of Young Stellar Objects. IV. Detailed Imaging of the Protoplanetary Disk around TW Hya

JWST/NIRCam Imaging of Young Stellar Objects. IV. Detailed Imaging of the Protoplanetary Disk around TW Hya

Posted by klaurent Peking

Kavli Affiliate: Ruobing Dong | Summary:As the nearest protoplanetary disk to Earth ($d = 60.14$ pc), TW Hya is one of the most studied protoplanetary disks and a critical benchmark for testing planet formation theories. We present high-contrast coronagraphic imaging of the TW Hya disk from JWST/NIRCam across four filters (F187N, F200W, F356W, and F444W). […]


Continue.. JWST/NIRCam Imaging of Young Stellar Objects. IV. Detailed Imaging of the Protoplanetary Disk around TW Hya