Social Novelty Recruits a Dysfunctional Nucleus Accumbens Ensemble That Drives Social Avoidance in a Shank3-/- Autism Model

Posted by dbos Yale

Kavli Affiliate: Marina Picciotto | Authors: Oakleigh M Folkes, Meaghan Donahue, Rafael E Perez, Angélica Minier-Toribio, Paola N. Negrón-Moreno, Marina R. Picciotto and Yong-Hui Jiang | Summary: Social behavior deficits are a common symptom of neuropsychiatric disorders, including autism spectrum disorder (ASD), but there are limited pharmacological treatments for these symptoms. Understanding how neurons encode […]


Continue.. Social Novelty Recruits a Dysfunctional Nucleus Accumbens Ensemble That Drives Social Avoidance in a Shank3-/- Autism Model

Flexible route planning and rapid structure learning by mice in complex environments

Posted by dbos Columbia

Kavli Affiliate: Rui Costa | Authors: Michael Pereira, Beatriz S. Godinho, Christian K. Machens, Rui M. Costa and Thomas Akam | Summary: Action selection using predictive models of the environment plays a fundamental role in human and animal behaviour, yet is poorly understood at circuit and algorithmic levels. Spatial navigation is an attractive domain for […]


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Redox-Active Halide Materials for Cathode Applications

Posted by klaurent Berkeley

Kavli Affiliate: Gerbrand Ceder| Summary:Electrochemically redox-active halide (eREAL) materials are an emerging class of materials that combine high Li-ion conductivity with transition-metal redox activity, making them promising candidates for cathode or catholyte applications. As a redox-active catholyte, they could significantly increase the energy density of solid-state batteries. In this work, we perform first-principles calculations on […]


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TLR4 signaling drives tissue inflammation, Claudin-5 internalization, and vascular barrier breakdown in a mouse model of neonatal meningitis

Posted by dbos Hopkins

Kavli Affiliate: Jeremy Nathans | Authors: Philip V Seegren, Amir Rattner, Philip M Smallwood and Jeremy Nathans | Summary: Neonatal bacterial meningitis is a leading cause of infant morbidity and mortality, yet the molecular and cellular basis of the leptomeningeal response to infection remains poorly defined. Here, we study a mouse model of neonatal E. […]


Continue.. TLR4 signaling drives tissue inflammation, Claudin-5 internalization, and vascular barrier breakdown in a mouse model of neonatal meningitis

Searches for GeV-Scale ALPs at RHIC

Posted by klaurent Tokyo

Kavli Affiliate: Hitoshi Murayama | Summary:We point out that ultra-peripheral Au+Au collision data collected at the Relativistic Heavy Ion Collider, operational during 2000-2026, can be used to search for axion-like particles coupled to photons via the resonant process $γγto a to γγ$. Exploiting the $Z^4$ enhancement of the two-photon luminosity in heavy-ion collisions and the […]


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Bulk Superconductivity driven by Disorder-Induced Delocalization in 4Hb-Ta(S$_1-x$Se$_x$)$_2$

Posted by klaurent Berkeley

Kavli Affiliate: James Analytis| Summary:The unconventional superconductor 4Hb-TaS$_2$ is a natural heterostructure that can be broadly understood as interleaving Mott-like and metallic layers. We study the properties of this material as a function of quenched disorder in the form of Se/S substitution and find that while disordered samples show bulk superconductivity, clean samples do not. […]


Continue.. Bulk Superconductivity driven by Disorder-Induced Delocalization in 4Hb-Ta(S$_1-x$Se$_x$)$_2$