Selective Vulnerability of Layer 5a Corticostriatal Neurons in Huntington’s Disease

Kavli Affiliate: Nathaniel Heintz | Authors: Christina Pressl, Kert Mätlik, Laura Kus, Paul Darnell, Ji-Dung Luo, Matthew R Paul, Alison R Weiss, William Liguore, Thomas Carroll, David A Davis, Jodi McBride and Nathaniel Heintz | Summary: The properties of the cell types that are most vulnerable in Huntington’s disease (HD) cortex, the nature of somatic […]


Continue.. Selective Vulnerability of Layer 5a Corticostriatal Neurons in Huntington’s Disease

Adaptive Fine-tuning based Transfer Learning for the Identification of MGMT Promoter Methylation Status

Kavli Affiliate: Jing Wang | First 5 Authors: Erich Schmitz, Yunhui Guo, Jing Wang, , | Summary: Glioblastoma Multiforme (GBM) is an aggressive form of malignant brain tumor with a generally poor prognosis. Treatment usually includes a mix of surgical resection, radiation therapy, and akylating chemotherapy but, even with these intensive treatments, the 2-year survival […]


Continue.. Adaptive Fine-tuning based Transfer Learning for the Identification of MGMT Promoter Methylation Status

Adaptive Fine-tuning based Transfer Learning for the Identification of MGMT Promoter Methylation Status

Kavli Affiliate: Jing Wang | First 5 Authors: Erich Schmitz, Yunhui Guo, Jing Wang, , | Summary: Glioblastoma Multiforme (GBM) is an aggressive form of malignant brain tumor with a generally poor prognosis. Treatment usually includes a mix of surgical resection, radiation therapy, and akylating chemotherapy but, even with these intensive treatments, the 2-year survival […]


Continue.. Adaptive Fine-tuning based Transfer Learning for the Identification of MGMT Promoter Methylation Status

The JADES Origins Field: A New JWST Deep Field in the JADES Second NIRCam Data Release

Kavli Affiliate: Roberto Maiolino | First 5 Authors: Daniel J. Eisenstein, Benjamin D. Johnson, Brant Robertson, Sandro Tacchella, Kevin Hainline | Summary: We summarize the properties and initial data release of the JADES Origins Field (JOF), which will soon be the deepest imaging field yet observed with the James Webb Space Telescope (JWST). This field […]


Continue.. The JADES Origins Field: A New JWST Deep Field in the JADES Second NIRCam Data Release

Development of covalent chemogenetic K2P channel activators

Kavli Affiliate: Daniel Minor | Authors: Parker E Deal, Haerim Lee, Abhisek Mondal, Marco Lolicato, Philipe Ribeiro Furtado de Mandonca, Holly Black, Xochina El-Hilali, Clifford Bryant, Ehud Y Isacoff, Adam Renslo and Daniel L Minor, Jr. | Summary: K2P potassium channels regulate excitability by affecting cellular resting membrane potential in the brain, cardiovascular system, immune […]


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Galaxy formation with Wave/Fuzzy Dark Matter: The core-halo structure

Kavli Affiliate: Mark Vogelsberger | First 5 Authors: Alvaro Pozo, Razieh Emami, Philip Mocz, Tom Broadhurst, Lars Hernquist | Summary: Dark matter-dominated cores have long been claimed for the well-studied local group dwarf galaxies. More recently, extended stellar halos have been uncovered around several of these dwarfs through deeper imaging and spectroscopy. Such core-halo structures […]


Continue.. Galaxy formation with Wave/Fuzzy Dark Matter: The core-halo structure

Probing the Galactic Diffuse Continuum Emission with COSI

Kavli Affiliate: Troy Porter | First 5 Authors: Christopher Karwin, Thomas Siegert, Jacqueline Beechert, John Tomsick, Troy Porter | Summary: In 2016 the Compton Spectrometer and Imager (COSI) had a successful 46-day flight onboard NASA’s Super Pressure Balloon platform. In this work we report measurements of the Galactic diffuse continuum emission (GDCE) observed towards the […]


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A Population of Short-duration Gamma-ray Bursts with Dwarf Host Galaxies

Kavli Affiliate: Alexander P. Ji | First 5 Authors: Anya E. Nugent, Wen-fai Fong, Cristian Castrejon, Joel Leja, Michael Zevin | Summary: We present a population of 11 of the faintest ($> 25.5$ AB mag) short gamma-ray burst (GRB) host galaxies. We model their sparse available observations using the stellar population inference code Prospector-$beta$ and […]


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A Dataset for Exploring Stellar Activity in Astrometric Measurements from SDO Images of the Sun

Kavli Affiliate: Andrew Vanderburg | First 5 Authors: Warit Wijitworasart, Zoe de Beurs, Andrew Vanderburg, , | Summary: We present a dataset for investigating the impact of stellar activity on astrometric measurements using NASA’s Solar Dynamics Observatory (SDO) images of the Sun. The sensitivity of astrometry for detecting exoplanets is limited by stellar activity (e.g. […]


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Simulating medium-spectral-resolution exoplanet characterization with SCALES angular/reference differential imaging

Kavli Affiliate: Bruce Macintosh | First 5 Authors: Aditi Desai, Stephanie E. Sallum, Ravinder Banyal, Natalie Batalha, Natasha Batalha | Summary: SCALES (Slicer Combined with Array of Lenslets for Exoplanet Spectroscopy) is a 2 – 5 micron high-contrast lenslet-based integral field spectrograph (IFS) designed to characterize exoplanets and their atmospheres. The SCALES medium-spectral-resolution mode uses […]


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