October 10, 2023 – Kavli Institute Pre-Print Publications

Mapping energy landscapes of homopolymeric RNAs via simulated tempering and deep unsupervised learning

Posted by dbos October 10, 2023October 23, 2023UCSD / Salk

Kavli Affiliate: V. S. Ramachandran | Authors: Vysakh Ramachandran and Davit A Potoyan | Summary: Conformational dynamics plays crucial roles in RNA functions about sensing and responding to environmental signals. The liquid-liquid phase separation of RNAs and the formation of stress granules partly relies on RNA’s conformational plasticity and its ability to engage in multivalent […]

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Substructure of the brain’s Cingulo-Opercular network

Posted by dbos October 10, 2023October 23, 2023UCSD / Salk

Kavli Affiliate: Deanna J. Greene | Authors: Carolina Badke D’Andrea, Timoth O Laumann, Dillan J Newbold, Steven M Nelson, Ashley N Nielsen, Roselyne Chauvin, Scott Marek, Deanna J. Greene, Nico U F Dosenbach and Evan M Gordon | Summary: HThe Cingulo-Opercular network (CON) is an executive network of the human brain that regulates actions. CON […]

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Phosphoglycerate kinase 1 is a central leverage point in Parkinson’s disease driven neuronal metabolic deficits

Posted by dbos October 10, 2023October 23, 2023Rockefeller, Yale

Kavli Affiliate: Timothy A. Ryan & Pietro De Camilli | Authors: Talex Kokotos, Aldana Antoniazzi, Santiago Unda, Myung Soo Kokotos, Daehun Park, David Eliezer, Michael Kaplitt, Pietro De Camilli and Timothy Ryan | Summary: Phosphoglycerate kinase 1 (PGK1), the first ATP producing glycolytic enzyme, has emerged as a therapeutic target for Parkinson’s Disease (PD), since […]

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Highly efficient visible and near-IR photon pair generation with thin-film lithium niobate

Posted by dbos October 10, 2023Caltech

Kavli Affiliate: Scott K. Cushing | First 5 Authors: Nathan A. Harper, Emily Y. Hwang, Ryoto Sekine, Luis Ledezma, Christian Perez | Summary: Efficient on-chip entangled photon pair generation at telecom wavelengths is an integral aspect of emerging quantum optical technologies, particularly for quantum communication and computing. However, moving to shorter wavelengths enables the use […]

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Suppression of epithelial proliferation and tumorigenesis by immunoglobulin A

Posted by dbos October 10, 2023October 23, 2023Rockefeller

Kavli Affiliate: Daniel Mucida | Authors: Gregory P. Donaldson, Gabriella L. Reis, Marwa Saad, Izabela Mamede, Guo Chen, Nicole L. DelGaudio, Dayu Zhang, Begum Aydin, Caroline E. Harrer, Tiago B.R. Castro, Sergei Grivennikov, Bernardo S. Reis, Beth M. Stadtmueller, Gabriel D. Victora and Daniel Mucida | Summary: Immunoglobulin A (IgA) is the most abundant antibody […]

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Highly efficient visible and near-IR photon pair generation with thin-film lithium niobate

Posted by dbos October 10, 2023October 23, 2023Caltech

Kavli Affiliate: Alireza Marandi | First 5 Authors: Nathan Harper, Emily Hwang, Ryoto Sekine, Luis Ledezma, Christian Perez | Summary: Efficient on-chip entangled photon pair generation at telecom wavelengths is an integral aspect of emerging quantum optical technologies, particularly for quantum communication and computing. However, moving to shorter wavelengths enables the use of more accessible […]

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Neurogenesis-mediated circuit remodeling reduces engram reinstatement and promotes forgetting

Posted by dbos October 10, 2023October 23, 2023UCSF

Kavli Affiliate: Xin Duan | Authors: Axel Guskjolen, Jagroop Dhaliwal, Juan de la Parra, Jonathan R Epp, Sangyoon Ko, Erin Chahley, Mitch de Snoo, Michela Solari, Prabdeep Panesar, Jason Scott Snyder, Xin Duan, Joshua Sanes, Sheena Josselyn and Paul Frankland | Summary: Post-training increases in hippocampal neurogenesis are associated with forgetting of hippocampus-dependent memories in […]

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Developmental origin and local signals cooperate to determine septal astrocyte identity

Posted by dbos October 10, 2023October 23, 2023UCSF

Kavli Affiliate: Arturo Alvarez-Buylla | Authors: Yajun Xie, Christopher M Reid, Alejandro A Granados, Miguel Turrero Garcia, Fiona Dale-Huang, Sarah M Hanson, Walter R Mancia Leon, Jonathan Liu, Manal A Adam, Olivia Mosto, Angela Oliveira Pisco, Arturo Alvarez-Buylla and Corey C Harwell | Summary: Astrocyte specification during development is influenced by both intrinsic and extrinsic […]

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The look of high-velocity red-giant star collisions

Posted by dbos October 10, 2023Peking

Kavli Affiliate: Pau Amaro Seoane | First 5 Authors: Luc Dessart, Taeho Ryu, Pau Amaro Seoane, Andrew M. Taylor, | Summary: High-velocity stellar collisions driven by a supermassive black hole (BH) or BH-driven disruptive collisions, in dense, nuclear clusters can rival the energetics of supergiant star explosions following gravitational collapse of their iron core. Here, […]

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Brain state and cortical layer-specific mechanisms underlying perception at threshold

Posted by klaurent October 10, 2023October 23, 2023UCSD / Salk, Yale

Kavli Affiliate: Anirvan Nandy, John Reynolds | Authors: Mitchell P Morton, Sachira Denagamage, Isabel J Blume, John H Reynolds, Monika P Jadi and Anirvan S Nandy | Summary: Identical stimuli can be perceived or go unnoticed across successive presentations, producing divergent behavioral outcomes despite similarities in sensory input. We sought to understand how fluctuations in […]

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