Kavli Affiliate: Lihong V. Wang
| First 5 Authors: David C. Garrett, Jinhua Xu, Yousuf Aborahama, Geng Ku, Konstantin Maslov
| Summary:
Ultrasonography is a vital component of modern clinical care, with handheld
probes routinely used for diagnostic imaging and procedural guidance. However,
handheld ultrasound imaging is limited by factors such as the
partial-cross-sectional field of view, operator dependency, contact-induced
distortion, and lack of transmission contrast. Here, we demonstrate a new
system enabling whole cross-sectional ultrasound tomography of humans in
reflection and transmission modes. We generate 2D images of the entire in vivo
human cross-section with uniform in-plane resolution using a custom 512-element
circular ultrasound receiver array and a rotating ultrasonic transmitter. We
demonstrate this technique in regions such as the abdomen and legs in healthy
volunteers. To address unmet clinical needs, we explore two key applications.
First, we readily observe abdominal adipose distributions in our images,
enabling adipose thickness assessment over the body without ionizing radiation
or mechanical deformation. Second, we demonstrate an approach for video-rate
(30 frame-per-second) biopsy needle localization with respect to internal
tissue features. These capabilities make whole cross-sectional ultrasound
tomography a potential practical tool for clinical needs not currently met by
other modalities.
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